Zobrazeno 1 - 10
of 28
pro vyhledávání: '"F. C. Lam"'
Publikováno v:
Marine Drugs, Vol 18, Iss 8, p 404 (2020)
The cytotoxic marine natural product discorhabdin C contains a 2,6-dibromo-cyclohexa-2,5-diene moiety, previously proposed to be a critical feature required for biological activity. We have determined that the dienone-ring of discorhabdin C is indeed
Externí odkaz:
https://doaj.org/article/5b3f4b2bfe1348e096a0125cc1f3859f
Publikováno v:
Marine Drugs, Vol 11, Iss 9, Pp 3472-3499 (2013)
Pure compound screening has identified the dioxothiazino-quinoline-quinone ascidian metabolite ascidiathiazone A (2) to be a moderate growth inhibitor of Trypanosoma brucei rhodesiense (IC50 3.1 μM) and Plasmodium falciparum (K1 dual drug resistant
Externí odkaz:
https://doaj.org/article/07ff922b307348f681b3e87d628895f7
Publikováno v:
Marine Drugs
Marine Drugs, Vol 18, Iss 404, p 404 (2020)
Volume 18
Issue 8
Marine Drugs, Vol 18, Iss 404, p 404 (2020)
Volume 18
Issue 8
The cytotoxic marine natural product discorhabdin C contains a 2,6-dibromo-cyclohexa-2,5-diene moiety, previously proposed to be a critical feature required for biological activity. We have determined that the dienone-ring of discorhabdin C is indeed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc129b77d10daf1e785b8398e333f9e7
https://pubmed.ncbi.nlm.nih.gov/32752009
https://pubmed.ncbi.nlm.nih.gov/32752009
Publikováno v:
Tetrahedron. 73:4779-4785
In order to clarify the importance of the C-3 carbonyl group to the cytotoxicity observed for discorhabdin marine alkaloids a number of semi-synthetic analogues of discorhabdin P were prepared. C-3 Reduction and acetylation typically resulted in a 4-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2d225fad9e0d6bdae15cb0efec00f04d
https://doi.org/10.1016/j.tet.2017.06.057
https://doi.org/10.1016/j.tet.2017.06.057
Publikováno v:
Eye. 28:1297-1303
To investigate patient risk factors and to look for potential causes of sterile infiltrates following an unexpected cluster of sterile keratitis after a routine collagen cross-linking (CXL) list.The records of all 148 cases of CXL were reviewed retro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::737a7bcda473059cbdc83c0bd7173345
https://doi.org/10.1038/eye.2014.173
https://doi.org/10.1038/eye.2014.173
Publikováno v:
Tetrahedron. 68:3187-3194
Semi-synthetic N-13 alkylated analogues of the cytotoxic marine alkaloid discorhabdin C have been found to exhibit cytotoxicity towards tumour cell lines at comparable levels to that of the natural product. Incorporation of an ethylenediamine linker
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6c05c5d5a8ddc99e29cf3c37b2bfd31e
https://doi.org/10.1016/j.tet.2012.02.052
https://doi.org/10.1016/j.tet.2012.02.052
Autor:
Catherine Sm Chan, Angela Yq Liang, Lixing Lao, Brian Berman, David Tw Yew, Justin C.Y. Wu, Joseph J.Y. Sung, Eric Tc Ziea, Sunny Lh Chu, Emma F C Lam
Publikováno v:
Journal of Neurogastroenterology and Motility
Background/Aims While it is well established that acupuncture relieves somatic pain, its therapeutic effect on visceral pain such as irritable bowel syndrome (IBS) is unclear. We evaluated the effect of acupuncture in treating visceral hyperalgesia i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9780d903fe18696861383f1f6ef5dee
http://europepmc.org/articles/PMC2912124
http://europepmc.org/articles/PMC2912124
Blue-blocking intraocular implants should be used routinely during phacoemulsification surgery – Yes
Publikováno v:
Eye. 26:1397-1399
Blue-blocking intraocular implants should be used routinely during phacoemulsification surgery – Yes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f193d469fa30f0086d8393e249e33b3
https://doi.org/10.1038/eye.2012.178
https://doi.org/10.1038/eye.2012.178
Publikováno v:
Eye. 21:847-849
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::51d1a99f209e07943c559fd10b75da3c
https://doi.org/10.1038/sj.eye.6702703
https://doi.org/10.1038/sj.eye.6702703
Autor:
Wendy Law, Siew C. Ng, Tommy Tsan-Yuk Lam, Yawen Chan, Joseph J.Y. Sung, Michael A. Kamm, Justin C.Y. Wu, Pete C.H. Tse, Francis K.L. Chan, Emma F C Lam
Publikováno v:
Journal of gastroenterology and hepatology. 28(10)
Background and Aim In irritable bowel syndrome (IBS), the gut microbiota may be altered. Probiotic bacteria appear to be therapeutically effective. We characterized the mucosa-associated microbiota, and determined the clinical and microbiological eff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5baee69b45f175a4ed2ac1f0fec7048c
https://pubmed.ncbi.nlm.nih.gov/23800182
https://pubmed.ncbi.nlm.nih.gov/23800182