Zobrazeno 1 - 6
of 6
pro vyhledávání: '"F. C. Falkner"'
Autor:
R P, Robinson, L A, Reiter, W E, Barth, A M, Campeta, K, Cooper, B J, Cronin, R, Destito, K M, Donahue, F C, Falkner, E F, Fiese, D L, Johnson, A V, Kuperman, T E, Liston, D, Malloy, J J, Martin, D Y, Mitchell, F W, Rusek, S L, Shamblin, C F, Wright
Publikováno v:
Journal of Medicinal Chemistry. 39:10-18
Ether, ester, and carbonate derivatives of the antirheumatic oxindole 1 were prepared and screened as potential prodrugs of 1. This effort led to the discovery of the (alpha-L-alanyloxy)-methyl ether and hemifumarate derivatives of 1 which deliver th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64fdac7758c1167da4b6f3a5469dc7d5
https://doi.org/10.1021/jm950575k
https://doi.org/10.1021/jm950575k
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 25(2)
Tenidap is a new antirheumatic drug currently undergoing clinical evaluation. It inhibits production and activity of cytokines in vivo and causes significant reductions in plasma markers of disease activity in rheumatoid arthritis. After the oral adm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6c570591fc368ce0ca1d5071545ca305
https://pubmed.ncbi.nlm.nih.gov/9029043
https://pubmed.ncbi.nlm.nih.gov/9029043
Autor:
Mary J. Mackie, F. C. Falkner, Paula V. Mayshar, J. D. Lazar, Timothy C. Fagan, Kenneth A. Conrad, J. F. Souhrada, Stanley M. Lee
Publikováno v:
European Journal of Clinical Pharmacology. 35:21-24
The antihypertensive effects and steady-state pharmacokinetics of doxazosin, as well as the bioequivalence of four dosage forms, were studied in 25 hypertensive patients. For an 8 mg daily dose mean Cmax at steady-state for all patients was 108 ng/ml
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d493183f4ba372527762902a39b3f344
https://doi.org/10.1007/bf00555502
https://doi.org/10.1007/bf00555502
Publikováno v:
Biomedical mass spectrometry. 1(2)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::975d239bf08dcf08c62ecffb9075c632
https://pubmed.ncbi.nlm.nih.gov/4433730
https://pubmed.ncbi.nlm.nih.gov/4433730
Autor:
F C, Falkner
Publikováno v:
Biomedical mass spectrometry. 4(1)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::cc3a1eb044efd8fc03a7096066bd41e4
https://pubmed.ncbi.nlm.nih.gov/836947
https://pubmed.ncbi.nlm.nih.gov/836947
Autor:
F. C. Falkner, J. H. Hengstmann
Publikováno v:
European journal of clinical pharmacology. 15(2)
The plasma level and urinary excretion rate of guanethidine have been measured in 30 patients during oral maintenance therapy, and in 5 patients following discontinuation of therapy. A significant correlation was found between the daily average urina
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::354b857a7f18f09b0252f0c4c502272b
https://pubmed.ncbi.nlm.nih.gov/374089
https://pubmed.ncbi.nlm.nih.gov/374089