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Expression of chemokines and their receptors in human and simian astrocytes: Evidence for a central role of TNFα and IFNγ in CXCR4 and CCR5 modulation

Autor: Barbara Mognetti, Bruce J. Brew, Laure I. Gigout, Dominique Dormont, Arnaud Chéret, F. Boussin, Juliana Croitoru-Lamoury, Gilles J. Guillemin, Roger Le Grand, Bruno Vaslin

Publikováno v: Glia. 41:354-370

Chemokines are key mediators of the selective migration of leukocytes that occurs in neurodegenerative diseases and related inflammatory processes. Astrocytes, the most abundant cell type in the CNS, have an active role in brain inflammation. To asce

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8ba8efe9cdef14a6a7a81c4566809d79
https://doi.org/10.1002/glia.10181

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Astrocyte gene expression in experimental mouse scrapie

Autor: M. Tardy, F. Boussin, Jean-Philippe Deslys, Françoise Lazarini, D. Dormont

Publikováno v: Journal of Comparative Pathology. 111:87-98

Summary The biological hallmark of transmissible spongiform encephalopathies is a significant accumulation, in brain, of the scrapie prion protein (PrPsc), often associated with an increased glial fibrillary acidic protein (GFAP) expression. This stu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4f496160eb5666f0f22477f1b881823
https://doi.org/10.1016/s0021-9975(05)80114-8

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Antibody-dependent cellular cytotoxicity and neutralization of human immunodeficiency virus type 1 by high affinity cross-linking of gp41 to human macrophage Fc IgG receptor using bispecific antibody

Autor: Aloïse Mabondzo, Bruno Vaslin, J. Bartholeyns, Hervé Raoul, R. Le Naour, J.-L. Romet-Lemonne, Dominique Dormont, F. Boussin, G. Gras

Publikováno v: Scopus-Elsevier

Human monocytes/macrophages, which express Fc receptors for IgG are involved in human immunodeficiency virus type 1 (HIV-1) infection and pathogenesis. These receptors are known to mediate numerous immunological functions including cell-mediated kill

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5ef731a14f5cdb0c89f82f4b44e962d
https://doi.org/10.1099/0022-1317-75-6-1451

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Na+-dependent high-affinity glutamate transport in macrophages

Autor: Dominique Dormont, F. Boussin, Gabriel Gras, Anne-Cécile Rimaniol, Roger Le Grand, Nathalie Dereuddre-Bosquet, Stéphane Haïk, Marc Martin

Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 164(10)

Excessive accumulation of glutamate in the CNS leads to excitotoxic neuronal damage. However, glutamate clearance is essentially mediated by astrocytes through Na+-dependent high-affinity glutamate transporters (excitatory amino acid transporters (EA

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a0ced3b67570c9246c3be551de4e9a7
https://pubmed.ncbi.nlm.nih.gov/10799909

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Chemoattractant factors (IP-10, MIP-1alpha, IL-16) mRNA expression in mononuclear cells from different tissues during acute SIVmac251 infection of macaques

Autor: Frank Matheux, Arnaud Chéret, Dominique Dormont, Bruno Vaslin, F. Boussin, Roger Le Grand, Frédéric Théodora, P Caufour, O. Neildez

Publikováno v: Journal of medical primatology. 26(1-2)

We have used semiquantitative RT-PCR to monitor the expression of mRNA encoding chemoattractant factors IP-10, MIP-1alpha, and IL-16 in freshly isolated peripheral blood mononuclear cells (PBMCs), lymph node mononuclear cells (LNMCs), and mononuclear

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bc4081920d0a4b2f407c2543d4d2ee7
https://pubmed.ncbi.nlm.nih.gov/9271185

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Akademický článek

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Inactivation of human immunodeficiency virus during human growth hormone production

Autor: F. Boussin, F. Maillard, D. Dubeaux, B. Vaslin, J. P. Deslys, D. Dormont

Publikováno v: Archives of Virology. 100:135-138

Since human immunodeficiency virus (HIV) has been found in the brains of AIDS patients, the possibility was investigated that preparations of human growth hormone (hGH) extracted from human pituitary glands harbor infectious HIV. It was found that th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::810e1888822dbc5561ac8552e0ef6b97
https://doi.org/10.1007/bf01310916

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Isolation of HIV in a seronegative demented patient without symptoms of immune deficiency

Autor: F, Boussin, D, Dormont, B, Spire, H, Fleury, F, Rey, D, Bequet, J, Goasguen, P, Brunet

Publikováno v: Cancer detection and prevention. 12(1-6)

A 60-year-old male patient, originating from West Africa, developed acute and regressive neurologic symptoms associated with aphasia, apraxia, acalculia, behavioral impairments, and an epileptic phase. Eighteen months after the onset of the disease,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::0eacfd6fa9dfcf38bf66bbe9f503783d
https://pubmed.ncbi.nlm.nih.gov/3180131

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