Zobrazeno 1 - 10
of 512
pro vyhledávání: '"F. Boland"'
Autor:
D. J. Murphy, Y. Shahabuddin, S. Yambasu, K. O’Donoghue, D. Devane, A. Cotter, G. Gaffney, L. A. Burke, E. J. Molloy, F. Boland
Publikováno v:
Trials, Vol 23, Iss 1, Pp 1-13 (2022)
Abstract Background Cardiotocography (CTG) is a screening test used to detect fetal hypoxia in labour. It has a high false positive rate resulting in many potentially unnecessary caesarean sections. Fetal blood sampling (FBS) is a second-line test of
Externí odkaz:
https://doaj.org/article/f8a1745a3fc34822a7a90f0bea29e1da
Autor:
Karen Cardwell, B. Clyne, F. Moriarty, E. Wallace, T. Fahey, F. Boland, L. McCullagh, S. Clarke, K. Finnigan, M. Daly, M. Barry, S. M. Smith, on behalf of the General Practice Pharmacist (GPP) Study Group
Publikováno v:
Pilot and Feasibility Studies, Vol 4, Iss 1, Pp 1-11 (2018)
Abstract Background Prescribing for patients taking multiple medicines (i.e. polypharmacy) is challenging for general practitioners (GPs). Limited evidence suggests that the integration of pharmacists into the general practice team could improve the
Externí odkaz:
https://doaj.org/article/e82f86620ac94066a38b85339209b8f8
Somatic mutations in 3929 HPV positive cervical cells associated with infection outcome and HPV type
Autor:
Maisa Pinheiro, Nicolas Wentzensen, Michael Dean, Meredith Yeager, Zigui Chen, Amulya Shastry, Joseph F. Boland, Sara Bass, Laurie Burdett, Thomas Lorey, Sambit Mishra, Philip E. Castle, Mark Schiffman, Robert D. Burk, Bin Zhu, Lisa Mirabello
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract Invasive cervical cancers (ICC), caused by HPV infections, have a heterogeneous molecular landscape. We investigate the detection, timing, and HPV type specificity of somatic mutations in 3929 HPV-positive exfoliated cervical cell samples fr
Externí odkaz:
https://doaj.org/article/c1bcd6c690174c39b5a8206f244b5eba
Autor:
Bin Zhu, Yanzi Xiao, Meredith Yeager, Gary Clifford, Nicolas Wentzensen, Michael Cullen, Joseph F. Boland, Sara Bass, Mia K. Steinberg, Tina Raine-Bennett, DongHyuk Lee, Robert D. Burk, Maisa Pinheiro, Lei Song, Michael Dean, Chase W. Nelson, Laurie Burdett, Kai Yu, David Roberson, Thomas Lorey, Silvia Franceschi, Philip E. Castle, Joan Walker, Rosemary Zuna, Mark Schiffman, Lisa Mirabello
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
The APOBEC mutational signature is prevalent in different tumour types. Here, using HPV16- positive cervical samples, the authors show that the signature is more prevalent in the viral genome of benign or clearing HPV16 infections compared to the vir
Externí odkaz:
https://doaj.org/article/a712b17c7277429d9923c92438580cdd
Autor:
Hong Lou, Joseph F. Boland, Hongchuan Li, Robert Burk, Meredith Yeager, Stephen K. Anderson, Nicolas Wentzensen, Mark Schiffman, Lisa Mirabello, Michael Dean
Publikováno v:
Cancers, Vol 14, Iss 19, p 4895 (2022)
The human papillomavirus (HPV) type 16 E7 oncogene is critical to carcinogenesis and highly conserved. Previous studies identified a preponderance of non-synonymous E7 variants amongst HPV16-positive cancer-free controls compared to those with cervic
Externí odkaz:
https://doaj.org/article/7e9dd33e1fa4446c8a6eb35d2f53053c
Autor:
Nicole M. Rossi, Jieqiong Dai, Yi Xie, Darawalee Wangsa, Kerstin Heselmeyer-Haddad, Hong Lou, Joseph F. Boland, Meredith Yeager, Roberto Orozco, Enrique Alvirez Freites, Lisa Mirabello, Eduardo Gharzouzi, Michael Dean
Publikováno v:
Cancer Research. :OF1-OF14
HPV16 is the most oncogenic type of human papillomaviruses (HPV). Integration of HPV into the human genome is an important mechanism of carcinogenesis but is absent in at least 30% of HPV16+ tumors. We applied long-read whole-genome sequencing (WGS)
Autor:
Maisa Pinheiro, Ariana Harari, Mark Schiffman, Gary M. Clifford, Zigui Chen, Meredith Yeager, Michael Cullen, Joseph F. Boland, Tina Raine-Bennett, Mia Steinberg, Sara Bass, Yanzi Xiao, Vanessa Tenet, Kai Yu, Bin Zhu, Laurie Burdett, Sevilay Turan, Thomas Lorey, Philip E. Castle, Nicolas Wentzensen, Robert D. Burk, Lisa Mirabello
Publikováno v:
Viruses, Vol 13, Iss 10, p 1948 (2021)
Human papillomavirus (HPV) type 31 (HPV31) is closely related to the most carcinogenic type, HPV16, but only accounts for 4% of cervical cancer cases worldwide. Viral genetic and epigenetic variations have been associated with carcinogenesis for othe
Externí odkaz:
https://doaj.org/article/327f4d5e4a4747b29f455b35ec2e8b73
Autor:
Daniel L. Faden, Krystle A. Lang Kuhs, Maoxuan Lin, Adam Langenbucher, Maisa Pinheiro, Meredith Yeager, Michael Cullen, Joseph F. Boland, Mia Steinberg, Sara Bass, James S. Lewis, Michael S. Lawrence, Robert L. Ferris, Lisa Mirabello
Publikováno v:
Viruses, Vol 13, Iss 8, p 1666 (2021)
APOBEC is a mutagenic source in human papillomavirus (HPV)-mediated malignancies, including HPV+ oropharyngeal squamous cell carcinoma (HPV + OPSCC), and in HPV genomes. It is unknown why APOBEC mutations predominate in HPV + OPSCC, or if the APOBEC-
Externí odkaz:
https://doaj.org/article/4876a4f80f6449fcaf4f7085f50b8efc
Autor:
Michael Dean, Eduardo Gharzouzi, Lisa Mirabello, Enrique Alvirez Freites, Roberto Orozco, Meredith Yeager, Joseph F. Boland, Hong Lou, Kerstin Heselmeyer-Haddad, Darawalee Wangsa, Yi Xie, Jieqiong Dai, Nicole M. Rossi
Supplemental tables
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cb830cf9a3674f433b7789e4c4577d6
https://doi.org/10.1158/0008-5472.22929981
https://doi.org/10.1158/0008-5472.22929981
Autor:
Michael Dean, Eduardo Gharzouzi, Lisa Mirabello, Enrique Alvirez Freites, Roberto Orozco, Meredith Yeager, Joseph F. Boland, Hong Lou, Kerstin Heselmeyer-Haddad, Darawalee Wangsa, Yi Xie, Jieqiong Dai, Nicole M. Rossi
Supplementary figures
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bde6d333b9868641726c99f07ff56b68
https://doi.org/10.1158/0008-5472.22929978.v1
https://doi.org/10.1158/0008-5472.22929978.v1