A reduced level of consciousness affects non-conscious processes

Autor: A. Fontan, L. Lindgren, T. Pedale, C. Brorsson, F. Bergström, J. Eriksson

Publikováno v: NeuroImage, Vol 244, Iss , Pp 118571- (2021)

Being conscious is a profound aspect of human existence, and understanding its function and its inception is considered one of the truly grand scientific challenges. However, the nature of consciousness remains enigmatic, to a large part because “b

Externí odkaz: https://doaj.org/article/5380eee5d0e942fd96b820eacb2f9eba

An ABCA4 loss-of-function mutation causes a canine form of Stargardt disease.

Autor: Suvi Mäkeläinen, Marta Gòdia, Minas Hellsand, Agnese Viluma, Daniela Hahn, Karim Makdoumi, Caroline J Zeiss, Cathryn Mellersh, Sally L Ricketts, Kristina Narfström, Finn Hallböök, Björn Ekesten, Göran Andersson, Tomas F Bergström

Publikováno v: PLoS Genetics, Vol 15, Iss 3, p e1007873 (2019)

Autosomal recessive retinal degenerative diseases cause visual impairment and blindness in both humans and dogs. Currently, no standard treatment is available, but pioneering gene therapy-based canine models have been instrumental for clinical trials

Externí odkaz: https://doaj.org/article/440e2dd2ef7541c0a70a7c12f3d6f9ec

Rapid changes in profiles from stored materials used in scent training of explosive detection dogs

Autor: L. Mörén, F. Bergström, M. Brantlind, H. Wingfors

Publikováno v: Sciencejustice : journal of the Forensic Science Society. 62(5)

Canines trained on scents from materials emitting vapours of explosives and related compounds are widely used to detect explosives in civilian, military and forensic applications. Despite the importance of these training materials, there is limited k

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36658fb752cec650ea485882ace64571
https://pubmed.ncbi.nlm.nih.gov/36336459

A novel canine reference genome resolves genomic architecture and uncovers transcript complexity

Autor: Henrik Rönnberg, Maja-Louise Arendt, Gerli Pielberg, Elisabeth Sundström, Jennifer R. S. Meadows, Jens Häggström, Chao Wang, Jessika Nordin, Tomas F. Bergström, Jeanette Hanson, Ola Wallerman, Ingrid Ljungvall, Åsa Karlsson, Sara Saellström, Åsa Ohlsson, Åke Hedhammar, Suvi Mäkeläinen, Kerstin Lindblad-Toh

Publikováno v: Wang, C, Wallerman, O, Arendt, M L, Sundström, E, Karlsson, Å, Nordin, J, Mäkeläinen, S, Pielberg, G R, Hanson, J, Ohlsson, Å, Saellström, S, Rönnberg, H, Ljungvall, I, Häggström, J, Bergström, T F, Hedhammar, Å, Meadows, J R S & Lindblad-Toh, K 2021, ' A novel canine reference genome resolves genomic architecture and uncovers transcript complexity ', Communications Biology, vol. 4, 185 . https://doi.org/10.1038/s42003-021-01698-x
Communications Biology, Vol 4, Iss 1, Pp 1-11 (2021)
Communications Biology

We present GSD_1.0, a high-quality domestic dog reference genome with chromosome length scaffolds and contiguity increased 55-fold over CanFam3.1. Annotation with generated and existing long and short read RNA-seq, miRNA-seq and ATAC-seq, revealed th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64b98579921d02de00f53ef92eafa32e
https://pub.epsilon.slu.se/22751/

Deletion in the Bardet-Biedl Syndrome Gene TTC8 Results in a Syndromic Retinal Degeneration in Dogs

Autor: Suvi Mäkeläinen, Elina Andersson, Finn Hallböök, Cathryn S. Mellersh, Ingrid Ljungvall, Tomas F. Bergström, Göran Andersson, Minas Hellsand, Jens Häggström, Anna Darlene van der Heiden, Björn Ekesten, Elina Thorsson, Bodil Ström-Holst

In golden retriever dogs, a 1 bp deletion in the canine TTC8 gene has been shown to cause progressive retinal atrophy (PRA), the canine equivalent of retinitis pigmentosa. In humans, TTC8 is also implicated in Bardet-Biedl syndrome (BBS). To investig

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f8e5205f58399083678b54326e5f162b
https://doi.org/10.20944/preprints202008.0584.v1