Zobrazeno 1 - 10
of 37
pro vyhledávání: '"F. Benech-Kieffer"'
Autor:
Alexa Patzelt, Christèle Ribaud, Hans Schaefer, Jacques Leclaire, Heike Richter, F. Benech-Kieffer, Gerhard J. Nohynek, Hervé Toutain, Frédérique Hueber-Becker, Wolfram Sterry, Ute Jacobi, Eric K. Dufour, Juergen Lademann
Publikováno v:
Food and Chemical Toxicology. 46:2214-2223
Although in vitro skin absorption studies often detect small residues of applied test material in the epidermis/dermis, it is uncertain whether the residue is within the living skin. We studied the dermal absorption of a hair dye hydroxyanthraquinone
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6891ab1e43ffdc27c7e09646a19f5379
https://doi.org/10.1016/j.fct.2008.02.018
https://doi.org/10.1016/j.fct.2008.02.018
Publikováno v:
Skin Pharmacology and Physiology. 21:89-97
Percutaneous penetration studies are usually performed in human skin samples set up in a Franz® cell device. The ability to perform these studies may depend on the availability of skin samples. Reconstructed skin models are an interesting alternativ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7114f83d28e51fcc907c48a4e91599ef
https://doi.org/10.1159/000112959
https://doi.org/10.1159/000112959
Publikováno v:
Food and Chemical Toxicology. 42:517-543
Hair dyes and their ingredients have moderate to low acute toxicity. Human poisoning accidents are rare and have only been reported following oral ingestion. Contact sensitisation to hair dyes has been a safety issue, mainly as a consequence of unpro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::529a9064dbff1a0bc4f18f88a7387817
https://doi.org/10.1016/j.fct.2003.11.003
https://doi.org/10.1016/j.fct.2003.11.003
Publikováno v:
Skin Pharmacology and Physiology. 16:343-355
The potential human health risk of UV filters depends on their toxicity and the human systemic exposure which is a function of the extent of percutaneous absorption of the topically applied substance into the human organism. Using a ‘mass balance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::079449daae3ca090ca3a72f228d452df
https://doi.org/10.1159/000072929
https://doi.org/10.1159/000072929
Autor:
P. Wegrich, Hans Schaefer, G. Klecak, F. Benech-Kieffer, Jacques Leclaire, R. Schwarzenbach, T. Weber
Publikováno v:
Skin Pharmacology and Physiology. 13:324-335
Appropriate evaluation of sunscreens is required to provide better knowledge of their safety and efficacy. One of the most important elements of this evaluation is the assessment of percutaneous absorption. In vitro methods are largely used for such
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bde186666ecf147502a455fc7ab2ed04
https://doi.org/10.1159/000029940
https://doi.org/10.1159/000029940
Autor:
J Spengler, H Beck, P. Courtellemont, W. Steiling, Walter Diembeck, Marc Paye, Will W. Lovell, F. Benech-Kieffer, J. Dupuis
Publikováno v:
Food and Chemical Toxicology. 37:191-205
The following guidelines present an in vitro alternative, which uses excised animal or human skin, to experiments conducted in vivo on animals or humans for the assessment of dermal absorption and percutaneous penetration. Both aspects are essential
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::60bfe0d61dde658ba5e4612f11ad36be
https://doi.org/10.1016/s0278-6915(98)00114-8
https://doi.org/10.1016/s0278-6915(98)00114-8
Autor:
P. Boone, S. Hammer, F. Benech-Kieffer, Hidekazu Yamada, F. Yamazaki, A.-C. Goydadin, H. Brocvielle, C. Leclerc, Howard I. Maibach, Monika Schäfer-Korting, T. Yudate, P. Humbert, Jens-Uwe Grundmann, Harald Gollnick, F. Broly, Masaharu Matsukura, Gerhard J. Nohynek, Ulrike Blume-Peytavi, I. Brinkmann, R.G. Ramirez, Hongbo Zhai, Peter Elsner, J.-P. Kantelip, Len Roza, Uta-Christina Hipler, Jacques Leclaire, Ingrid Wiswedel, W.J.A. Meuling, A. Yajima, T. Tezuka, Tobias W. Fischer, U. Münster, Christel C. Müller-Goymann, D. Hirsch, Patrice Muret
Publikováno v:
Skin Pharmacology and Physiology. 16:415-417
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8c227bdf6ed7e09a0280f4073e7e0169
https://doi.org/10.1159/000073953
https://doi.org/10.1159/000073953
Autor:
F. Benech-Kieffer, Gerhard J. Nohynek, Frédérique Hueber-Becker, W.J.A. Meuling, Hervé Toutain
Publikováno v:
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 42(8)
We investigated the absorption of a commercial [14C]-PPD- containing oxidative dark-shade hair dye in human volunteers as well as in vitro using human or pig ear skin. The hair of eight male volunteers was cut to a standard length, dyed, washed, drie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb1517fd859f4161be2daf4201e88950
https://pubmed.ncbi.nlm.nih.gov/15207372
https://pubmed.ncbi.nlm.nih.gov/15207372
Publikováno v:
Skin pharmacology and applied skin physiology. 16(6)
The potential human health risk of UV filters depends on their toxicity and the human systemic exposure which is a function of the extent of percutaneous absorption of the topically applied substance into the human organism. Using a 'mass balance' ap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d1f91084863c56758671f0c552ee9061
https://pubmed.ncbi.nlm.nih.gov/14528058
https://pubmed.ncbi.nlm.nih.gov/14528058
