Zobrazeno 1 - 10
of 54
pro vyhledávání: '"F. Bamonte"'
Publikováno v:
Acta Pharmacologica et Toxicologica. 45:145-151
Reproductive and teratological studies were undertaken with netilmicin (Sch 20569), a new semisynthetic aminolgycoside antibiotic structurally related to sisomicin. The administration of 32 and 80 mg/kg/day, by the intramuscular route, in the rat pri
Publikováno v:
Therapeutic Drug Monitoring. 13:73-78
Isepamicin, the 1-N-(S-alpha-hydroxy-beta-aminopropionyl) derivative of gentamicin B, is a new aminoglycoside antibiotic, which not only has most of the properties of amikacin but also is effective against several amikacin-resistant strains of bacter
Publikováno v:
Chemotherapy. 36:33-40
To complement a study on aminoglycoside dosing regimen and ototoxicity in the guinea pig, we designed an experiment to examine: (1) the effect of dosing regimen on guinea pig pharmacokinetic parameters, and (2) possible differential accumulation afte
Publikováno v:
Journal of chemotherapy (Florence, Italy). 7
Groups of adult guinea pigs were treated intramuscularly with isepamicin at doses of 100, 150 and 225 mg/kg/day for 21 days. For comparison, two other groups were administered either saline or amikacin 225 mg/kg/day. Auditory function, as measured by
Publikováno v:
Journal of chromatography. 530(2)
Publikováno v:
Chemotherapy. 36(1)
Groups of guinea pigs were injected intramuscularly for 21 days with netilmicin or amikacin 150 mg/kg/day by one or three daily injections. Amikacin was also tested at 225 mg/kg/day with each dosing regimen. Auditory function was evaluated during the
Publikováno v:
Psychopharmacology. 86:132-136
The beta-carbolines, which are potent ligands for benzodiazepine receptors, antagonize the pharmacological actions of benzodiazepines. In the cat, the stable beta-carboline derivative methylamide-beta-carboline-3-carboxylate, FG 7142, and the specifi
Publikováno v:
Toxicology and Applied Pharmacology. 65:222-230
The ototoxicity of amikacin, gentamicin, netilmicin, and tobramycin in guinea pig, given daily sc doses for 3 weeks, was assessed and compared. Preyer pinna reflex evaluation and electrophysiologic auditory responses, such as brain stem-evoked respon
Publikováno v:
Archives of Oto-Rhino-Laryngology. 224:137-142
The following aminoglycoside antibiotics netilmicin, sisomicin, gentamicin, and kanamycin were submitted to a comparative study of their ototoxicity using both reflexological (Preyer's pinnareflex) and electrophysiological (near and far field) method
Publikováno v:
Archives of Oto-Rhino-Laryngology. 228:163-170
Twenty-one days s.c. treatment with netilmicin, gentamicin, sisomicin, and kanamicin at different doses were performed in albino guinea pigs of both sexes. Block surface preparation of Corti's organ was carried out and missing OHCs and IHCs counted i