Zobrazeno 1 - 10
of 381
pro vyhledávání: '"F. Arcamone"'
Publikováno v:
Antibioticschemotherapy (Northfield, Ill.). 6(4)
Publikováno v:
Biotechnology and Bioengineering. 67:704-713
Autor:
F, Arcamone, G, Cassinelli
Publikováno v:
Current Medicinal Chemistry. 5:391-419
This review summarizes the structure, the occurrence and the available data concerning the bioactivity of biosynthetic anthracyclines. The anthracyclines represent an important family of natural products produced by microorganisms of Streptomyces and
Autor:
Jaume Pascual, Maria Luisa García, David Mauleón, Germano Carganico, Liset Borras, F. Arcamone, J. A. Andreu, E. Fos
Publikováno v:
ChemInform. 23
Autor:
S, Spadari, G, Maga, F, Focher, G, Ciarrocchi, R, Manservigi, F, Arcamone, M, Capobianco, A, Carcuro, F, Colonna, S, Iotti
Publikováno v:
Journal of Medicinal Chemistry. 35:4214-4220
We have demonstrated that herpes simplex 1 (HSV1) thymidine kinase (TK) shows no stereospecificity for D- and L-beta-nucleosides. In vitro, L enantiomers are not recognized by human TK, but function as specific substrates for the viral enzyme in the
Publikováno v:
Biotechnology and bioengineering. 67(6)
Streptomyces peucetius var. caesius, obtained from S. peucetius, the daunomycin producing microorganism, by mutagenic treatment, differs from the parent culture by the color of the vegetative and aerial mycelia and by its antibiotic producing ability
Autor:
G, Pratesi, M, De Cesare, C, Caserini, P, Perego, L, Dal Bo, D, Polizzi, R, Supino, M, Bigioni, S, Manzini, E, Iafrate, C, Salvatore, A, Casazza, F, Arcamone, F, Zunino
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 4(11)
On the basis of a structure-activity study of a new series of anthracycline disaccharides, we recently identified a doxorubicin analogue (MEN 10755) with a promising antitumor activity. In the present study, to better support the pharmacological inte
Autor:
F, Animati, F, Arcamone, M, Bigioni, G, Capranico, C, Caserini, M, De Cesare, P, Lombardi, G, Pratesi, C, Salvatore, R, Supino, F, Zunino
Publikováno v:
Molecular pharmacology. 50(3)
In an attempt to better understand the role of the cyclohexene ring (ring A) in the biochemical and pharmacological properties of anthracyclines related to doxorubicin and daunorubicin, we investigated the effects of introduction of a fluorine atom a
Autor:
G, Cascio, L, Lorenzi, D, Caglio, E, Manghisi, F, Arcamone, G, Guanti, G, Satta, G, Morandotti, R, Sperning
Publikováno v:
Farmaco (Societa chimica italiana : 1989). 51(3)
New series of monobactam antibiotics, bearing thio-and dithiocarbamate derivatives as C-4 side chain, were synthesized. Some compounds were found to have good antibacterial activity against Gram-negative bacteria.