Zobrazeno 1 - 10
of 37
pro vyhledávání: '"F. A. Sirgel"'
Autor:
Susana Campino, Theolis Costa Barbosa Bessa, Nora Mocillo, Miguel Viveiros, Dang Minh Ha, Grant A. Hill-Cawthorne, Abdallah O Ahmed, Anirvan Chatterjee, Arnab Pain, Louis Grandjean, Julian Parkhill, Erivelton de Oliveira Sousa, Maxine Caws, Keertan Dheda, Abdallah M. Abdallah, Saad Alghamdi, João Perdigão, Elizabeth M. Streicher, Yaa Oppong, Nicholas Furnham, Stefan Panaiotov, Adriana Alves, Mridul Nair, Moses Joloba, Mona Alsomali, Edward C. Jones-López, Jaime Robledo, Nashwa Talaat Shesha, Zineb Rchiad, Martin L. Hibberd, Ruth McNerney, F. A. Sirgel, Stephanie Portelli, Robert M Warren, Carlos Penha, Christophe Sola, Isabel Portugal, Zahra Hasan, Amelia C. Crampin, Jody Phelan, Shahjahan Ali, Judith R. Glynn, Tomoshige Matsumoto, Rumina Hasan, Francesc Coll, Anabela Miranda, Kim Mallard, Paul D. van Helden, Taane G. Clark, David Moore, Patricia Sheen
Publikováno v:
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
This deposit is composed by a publication in which the IGC's authors have had the role of collaboration (it's a collaboration publication). This type of deposit in ARCA is in restrictedAccess (it can't be in open access to the public), and can only b
Autor:
Nicholas Furnham, Mridul Nair, Theolis Costa Barbosa Bessa, Miguel Viveiros, Christophe Sola, Isabel Portugal, Robert M Warren, Moses Joloba, Jody Phelan, Maxine Caws, Saad Alghamdi, Zahra Hasan, Nora Mocillo, Rumina Hasan, Francesc Coll, Dang Minh Ha, Patricia Sheen, Edward C. Jones-López, Jaime Robledo, Tomoshige Matsumoto, Judith R. Glynn, Elizabeth M. Streicher, Nashwa Talaat Shesha, Arnab Pain, Adriana Alves, Louis Grandjean, Yaa Oppong, Mona Alsomali, Paul D. van Helden, Taane G. Clark, Shahjahan Ali, Anirvan Chatterjee, Martin L. Hibberd, Stephanie Portelli, Anabela Miranda, Kim Mallard, Abdallah O Ahmed, F. A. Sirgel, Carlos Penha, David Moore, Keertan Dheda, Abdallah M. Abdallah, Erivelton de Oliveira Sousa, Julian Parkhill, João Perdigão, Stefan Panaiotov, Zineb Rchiad, Grant A. Hill-Cawthorne, Amelia C. Crampin, Susana Campino, Ruth McNerney
Publikováno v:
Nature Genetics
Nature Genetics, Nature Publishing Group, 2018, 50, pp.307-316. ⟨10.1038/s41588-017-0029-0⟩
Nature Genetics, 2018, 50, pp.307-316. ⟨10.1038/s41588-017-0029-0⟩
Nature Genetics, Nature Publishing Group, 2018, 50, pp.307-316. ⟨10.1038/s41588-017-0029-0⟩
Nature Genetics, 2018, 50, pp.307-316. ⟨10.1038/s41588-017-0029-0⟩
International audience; To characterize the genetic determinants of resistance to antituberculosis drugs, we performed a genome-wide association study (GWAS) of 6,465 $Mycobacterium\ tuberculosis$ clinical isolates from more than 30 countries. A GWAS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e582d147859ba8945b0591d02d3acf60
https://hdl.handle.net/20.500.12866/4080
https://hdl.handle.net/20.500.12866/4080
Autor:
Grant Theron, Leslie London, Marcus Low, Aliasgar Esmail, Ernesto Jaramillo, Stefan Niemann, Robin M. Warren, F. A. Sirgel, Kevin P. Fennelly, Edward A. Nardell, Tawanda Gumbo, Matthias Merker, Camilla Rodrigues, Megan Murray, Paul D. van Helden, Nesri Padayatchi, Anneke C. Hesseling, David W. Dowdy, Eric L. Nuermberger, C. Robert Horsburgh, Kelly E. Dooley, Keertan Dheda, Sachin R Atre, Gary Maartens, Taane G. Clark, Jennifer Furin, Eric Goemaere, Zarir F Udwadia, Ruth McNerney, Christoph Lange, Kwok Chiu Chang, Annelies Van Rie, Erica Lessem, H. Simon Schaaf, Hsien-Ho Lin, Gilman Kit Hang Siu, Carolina Morán Jara, Gavin J. Churchyard, Payam Nahid, Helen McIlleron, Dick Menzies, Jotam G. Pasipanodya
Publikováno v:
The lancet respiratory medicine
Global tuberculosis incidence has declined marginally over the past decade, and tuberculosis remains out of control in several parts of the world including Africa and Asia. Although tuberculosis control has been effective in some regions of the world
Autor:
Michael G. Whitfield, Alexandra Mercante, James E. Posey, Annelies Van Rie, Robin M. Warren, Melisa J. Willby, Kris Birkness, Paul D. van Helden, F. A. Sirgel, Elizabeth M. Streicher, Glenn P. Morlock, Kelsey Hughes, Samantha L. Sampson
Publikováno v:
Journal of clinical microbiology. 53(11)
Sequencing of the Mycobacterium tuberculosis pncA gene allows for pyrazinamide susceptibility testing. We summarize data on pncA polymorphisms that do not confer resistance at a susceptibility breakpoint of 100 μg/ml pyrazinamide in MGIT within a co
Autor:
Neesha Rockwood, Barbara Lazaro Mastrapa, Keertan Dheda, Julian te Riele, Jonny Peter, Paul D. van Helden, Elizabeth M. Streicher, Robin M. Warren, F. A. Sirgel, Malika Davids, Elize Pietersen
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0123655 (2015)
PLoS ONE
PLoS One
PLoS ONE
PLoS One
BACKGROUND: There are limited data about the epidemiology and treatment-related outcomes associated with capreomycin resistance in patients with XDR-TB. Capreomycin achieves high serum concentrations relative to MIC but whether capreomycin has therap
Publikováno v:
International Journal of Pharmaceutics. 307:182-187
This investigation retrospectively assessed inexpensive non-invasive qualitative methods to monitor the ingestion of anti-tuberculosis drugs isoniazid, rifampicin and rifapentine. Results showed that commercial test strips detected the isoniazid meta
Autor:
Jonathan Levin, Giorgio Roscigno, Jennifer Norman, F. A. Sirgel, Nesri Padayatchi, Denis A. Mitchison, Peter R. Donald, Helen McIlleron, P. Bernard Fourie, Roxana Rustomjee
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 172:128-135
Comparison of the early bactericidal activity (EBA) of rifapentine and its pharmacokinetics with those of rifampin to determine the cause of poor clinical response and regrowth between doses, leading to rifamycin monoresistance at relapse.Determinati
Autor:
Amour Venter, Cedric J. Werely, H. I. Seifart, Peter R. Donald, D. P. Parkin, B. W. Van de Wal, P. D. van Helden, F. A. Sirgel, J. S. Maritz
Publikováno v:
Clinical Infectious Diseases. 39:1425-1430
The elimination of isoniazid is subject to the influence of the N-acetyltransferase 2 (NAT2) genotype, and individuals may be homozygotic slow, heterozygotic fast, or homozygotic fast acetylators of isoniazid. The early bactericidal activity (EBA) of
Autor:
H. I. Seifart, B. W. Van de Wal, P. B. Fourie, F. A. Sirgel, D. P. Parkin Parkin, Amour Venter, J. S. Maritz, Peter R. Donald
Publikováno v:
Suid-Afrikaanse Tydskrif vir Natuurwetenskap en Tegnologie. 22:79-88
Die vroee bakterisidiese aktiwiteit (VBA) van ’n antituberkulosemiddel is die daaglikse afname van M tuberculosis in log10 kolonievormende eenhede per ml sputum, tydens die eerste twee dae van behandeling met die middel. Dit weerspieel die vermoe v
Autor:
P. R. Donald, F. A. Sirgel, A. Venter, P. B. Fourie, D. P. Parkin Parkin, H. I. Seifart, B. W. van de Wal, J. S. Maritz
Publikováno v:
South African Journal of Science and Technology, Vol 22, Iss 2&3, Pp 79-88 (2003)
South African Journal of Science and Technology, Vol 22, Iss 2/3, Pp 79-88 (2003)
South African Journal of Science and Technology, Vol 22, Iss 2/3, Pp 79-88 (2003)
Die vroeë bakterisidiese aktiwiteit (VBA) van ’n antituberkulosemiddel is die daaglikse afname van M tuberculosis in log10 kolonievormende eenhede per ml sputum, tydens die eerste twee dae van behandeling met die middel. Dit weerspieël die vermo