Zobrazeno 1 - 10
of 10
pro vyhledávání: '"F. A. Paczkowski"'
Publikováno v:
International Journal of Peptide Research and Therapeutics. 13:307-312
The 13-residue peptide, χ-conotoxin MrIA extracted from the venom of Conus marmoreus, is a potent and selective inhibitor of the human noradrenaline transporter (NET). With the aim of improving its biophysical properties, chemical modifications were
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a56b2ae8d29b4f30356d2a0af9176714
https://doi.org/10.1007/s10989-007-9083-2
https://doi.org/10.1007/s10989-007-9083-2
Publikováno v:
British Journal of Pharmacology. 143:63-70
1. The aim was to test the hypothesis that nitric oxide (NO) donor drugs can inhibit the 5-hydroxytryptamine (5-HT) transporter, SERT. 2. The NO donors, MAHMA/NO (a NONOate; (Z)-1-[N-methyl-N-[6-(N-methylammoniohexyl)-amino]]diazen-1-ium-1,2-diolate)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ab846248cc9c45c7977ee1f5e2ba4e43
https://doi.org/10.1038/sj.bjp.0705904
https://doi.org/10.1038/sj.bjp.0705904
Publikováno v:
Journal of Neurochemistry. 88:203-211
The aim was to investigate the roles of proline residues in extracellular loop 2 (P172, P183, P188 and P209) and transmembrane domains 2, 5, 11 and 12 (P108, P270, P526, P551, P552 and P570) in determining noradrenaline transporter (NET) expression a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f6b6c0bee2546711f9a09b074d47dbb3
https://doi.org/10.1111/j.1471-4159.2004.02149.x
https://doi.org/10.1111/j.1471-4159.2004.02149.x
Publikováno v:
Journal of Neurochemistry. 81:344-354
The aim of the study was to investigate the role of glutamate residue 113 in transmembrane domain 2 of the human noradrenaline transporter in determining cell surface expression and functional activity. This residue is absolutely conserved in all mem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ed2e2b4c502316b71bedb9d844401609
https://doi.org/10.1046/j.1471-4159.2002.00826.x
https://doi.org/10.1046/j.1471-4159.2002.00826.x
Publikováno v:
Naunyn-Schmiedeberg's Archives of Pharmacology. 365:312-317
It has been suggested from a previous study in our laboratory that differences in the pharmacology of the species variants of the noradrenaline transporter (NET) are the result of four non-conservative amino acid exchanges from the total of 26 amino
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b95a6e24c06704d70315e4c23cc641cc
https://doi.org/10.1007/s00210-002-0528-z
https://doi.org/10.1007/s00210-002-0528-z
Publikováno v:
Neuropharmacology. 40:607-617
The effects of short- and long-term exposure of cells to elevated cyclic adenosine monophosphate (c-AMP), using dibutyryl-c-AMP, 8-bromo-c-AMP, cholera toxin or forskolin, or cyclic guanosine monophosphate (c-GMP), using dibutyryl-c-GMP or 8-bromo-c-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8df7232fef9d756030977f18423cf2a
https://doi.org/10.1016/s0028-3908(00)00201-x
https://doi.org/10.1016/s0028-3908(00)00201-x
Publikováno v:
Journal of Biological Chemistry
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2007, 282 (24), pp.17837-17844. ⟨10.1074/jbc.M610813200⟩
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2007, 282 (24), pp.17837-17844. ⟨10.1074/jbc.M610813200⟩
International audience; Monoamine neurotransmitter transporters for norepinephrine (NE), dopamine and serotonin are important targets for antidepressants and analgesics. The conopeptide chi-MrIA is a noncompetitive and highly selective inhibitor of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80faaf5d626977ef413e996a7da77ec9
https://pubmed.ncbi.nlm.nih.gov/17428804
https://pubmed.ncbi.nlm.nih.gov/17428804
Autor:
F A, Paczkowski, L J, Bryan-Lluka
Publikováno v:
Journal of neurochemistry. 88(1)
The aim was to investigate the roles of proline residues in extracellular loop 2 (P172, P183, P188 and P209) and transmembrane domains 2, 5, 11 and 12 (P108, P270, P526, P551, P552 and P570) in determining noradrenaline transporter (NET) expression a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::aeed0bfc6ee4f7a86796ca418f7471c2
https://pubmed.ncbi.nlm.nih.gov/14675164
https://pubmed.ncbi.nlm.nih.gov/14675164
Publikováno v:
Brain research. Molecular brain research. 97(1)
The aim was to examine the functional importance in the norepinephrine transporter (NET) of (i) the phenylalanine residue at position 531 in transmembrane domain (TMD) 11 by mutating it to tyrosine in the rat (rF531Y) and human (hF531Y) NETs and (ii)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7a05d37a1a770ec99841bcdda27acca
https://pubmed.ncbi.nlm.nih.gov/11744160
https://pubmed.ncbi.nlm.nih.gov/11744160
Autor:
F. N. Paczkowski
Publikováno v:
10th Space Simulation Conference.
There is a continuing interest and need for investigation and development of, various paints, coatings, multi-layer insulation, and electrically conductive paints and coatings used for thermal control and electrical discharge of spacecraft surfaces.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3dfaffad848a3109e4a910c629dd2947
https://doi.org/10.2514/6.1978-1617
https://doi.org/10.2514/6.1978-1617