Zobrazeno 1 - 10
of 662
pro vyhledávání: '"F. A. Greco"'
Autor:
C. Wittenbecher, R. Cuadrat, L. Johnston, F. Eichelmann, S. Jäger, O. Kuxhaus, M. Prada, F. Del Greco M., A. A. Hicks, P. Hoffman, J. Krumsiek, F. B. Hu, M. B. Schulze
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
Among lipid classes, ceramides are linked to impaired cardiometabolic health. Here the authors report the association of specific ceramides and dihydroceramides on the risk of developing type 2 diabetes and or cardiovascular disease in a prospective
Externí odkaz:
https://doaj.org/article/ef9e0a95525d4f258560ce9666c9bb19
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
Inducible gene expression systems should minimise leaky output and offer a large achievable range of expression. Here, the authors regulate transcription and translation together to suppress noise and create digital-like responses, while maintaining
Externí odkaz:
https://doaj.org/article/22f102bf191448c7a52806451b4bd2dc
Autor:
F. Anthony Greco
Publikováno v:
Translational Oncology, Vol 14, Iss 8, Pp 101092- (2021)
Externí odkaz:
https://doaj.org/article/95b4a5517dcd40b3bc1aadd4ba07c53f
Autor:
Gauri R. Varadhachary, Jonathan M. Loree, F. Anthony Greco, Xuemei Wang, Michael J. Overman, Justin Jao, Jeannelyn S. Estrella, Aurelio Matamoros, Brandon Smaglo, Jignesh Modha, Nishat P. Dhillon, Ryan W. Huey, Anneleis Willett, Eric Bhang, Alexandre A. Jácome, Hyunsoo Hwang, Kanwal Raghav
Supplementary Data
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d20c3c4a065e8e087654d5ef973b291
https://doi.org/10.1158/1078-0432.22479951.v1
https://doi.org/10.1158/1078-0432.22479951.v1
Autor:
Gauri R. Varadhachary, Jonathan M. Loree, F. Anthony Greco, Xuemei Wang, Michael J. Overman, Justin Jao, Jeannelyn S. Estrella, Aurelio Matamoros, Brandon Smaglo, Jignesh Modha, Nishat P. Dhillon, Ryan W. Huey, Anneleis Willett, Eric Bhang, Alexandre A. Jácome, Hyunsoo Hwang, Kanwal Raghav
Purpose:Prognostic uncertainty is a major challenge for cancer of unknown primary (CUP). Current models limit a meaningful patient-provider dialogue. We aimed to establish a nomogram for predicting overall survival (OS) in CUP based on robust clinico
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78548ccbf7887cc2a3bdfe7e6d06690f
https://doi.org/10.1158/1078-0432.c.6530337.v1
https://doi.org/10.1158/1078-0432.c.6530337.v1
Autor:
Howard A. Burris, Jurgen Moll, Bernard Laffranchi, Silvia Comis, Roberta Ceruti, Maurizio Rocchetti, Mariangela Mariani, F. Anthony Greco, David R. Spigel, Jonathan Cheng, Margaret von Mehren, Charu Aggarwal, Suzanne F. Jones, Roger B. Cohen
Purpose: This study was conducted to assess the safety, tolerability, pharmacokinetics, and pharmacodynamics of the i.v. pan-aurora kinase inhibitor PHA-739358, danusertib, in patients with advanced solid tumors.Experimental Design: In part 1, patien
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f464a8357ae84ce0b861e75ce7c7794
https://doi.org/10.1158/1078-0432.c.6517320
https://doi.org/10.1158/1078-0432.c.6517320
Autor:
Howard A. Burris, Jurgen Moll, Bernard Laffranchi, Silvia Comis, Roberta Ceruti, Maurizio Rocchetti, Mariangela Mariani, F. Anthony Greco, David R. Spigel, Jonathan Cheng, Margaret von Mehren, Charu Aggarwal, Suzanne F. Jones, Roger B. Cohen
Supplementary Data from A Phase I Dose-Escalation Study of Danusertib (PHA-739358) Administered as a 24-Hour Infusion with and without Granulocyte Colony-Stimulating Factor in a 14-Day Cycle in Patients with Advanced Solid Tumors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34e396a140f5dd4ac23e5e39cd5e57d6
https://doi.org/10.1158/1078-0432.22439934
https://doi.org/10.1158/1078-0432.22439934
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2518
Precise control of gene expression is crucial when reprogramming the behavior of living cells. However, common inducible systems often lack the ability to stringently control gene expression due to the use of a single type of regulator that can be su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e124219d19ca2a202e725aa5fa7a645c
https://pubmed.ncbi.nlm.nih.gov/35666441
https://pubmed.ncbi.nlm.nih.gov/35666441
Autor:
Iris van der Strate, Fatemeh Kazemzadeh, Iris D. Nagtegaal, Debbie Robbrecht, Agnes van de Wouw, Catarina S. Padilla, Saskia Duijts, Manel Esteller, F. Anthony Greco, Nicholas Pavlidis, Amir Qaseem, Petur Snaebjornsson, Sophie Veldhuijzen van Zanten, Caroline Loef
Publikováno v:
SSRN Electronic Journal.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::14018a4ff9adcd892e6b7b4ff1c24d28
https://doi.org/10.2139/ssrn.4153460
https://doi.org/10.2139/ssrn.4153460
Autor:
Elie Rassy, Chris Labaki, Roy Chebel, Stergios Boussios, Julie Smith-Gagen, F. Anthony Greco, Nicholas Pavlidis
Publikováno v:
Cancer Treatment Reviews. 107:102407
Research on therapeutic strategies for patients with unknown primary cancer (CUP) has been underwhelming. This paper summarized and evaluated the CUP therapeutic research over the previous five years. Based on this evaluation, recommendations for cli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95328b987db888987d50bb8d070727c3
https://doi.org/10.1016/j.ctrv.2022.102407
https://doi.org/10.1016/j.ctrv.2022.102407