Zobrazeno 1 - 10
of 31
pro vyhledávání: '"F. Javier Díez‑Guerra"'
Autor:
F. Javier Díez Guerra
Publikováno v:
Arbor: Ciencia, Pensamiento y Cultura, Vol 177, Iss 698, Pp 225-258 (2004)
Durante los últimos años, las técnicas de microscopía óptica y sus aplicaciones han experimentado un auge sin precedentes. Más concretamente, la difusión de sistemas de microscopía confocal durante los 90 ha empujado con fuerza el desarrollo
Externí odkaz:
https://doaj.org/article/5d31c25790c34fe8a38a33bdfed18f59
Publikováno v:
PLoS ONE, Vol 9, Iss 7, p e102526 (2014)
We developed genetically-encoded fluorescent sensors based on Förster Resonance Energy Transfer to monitor phosphatidic acid (PA) fluctuations in the plasma membrane using Spo20 as PA-binding motif. Basal PA levels and phospholipase D activity varie
Externí odkaz:
https://doaj.org/article/2b4db936bd0b43d799282d9cd257c458
Autor:
Eva Delpón, Rafael J. Ramirez, Marcos Matamoros, Todd J. Herron, Daniela Ponce-Balbuena, Kuljeet Kaur, Héctor H. Valdivia, Manuel Zarzoso, Francisco J. Alvarado, B. Cicero Willis, Eric N. Jiménez-Vázquez, F. Javier Díez-Guerra, José Jalife, Ricardo Caballero, Carmen R. Valdivia, Andre Monteiro da Rocha, Guadalupe Guerrero-Serna, Marta Pérez-Hernández, Katherine Campbell
Publikováno v:
Circulation Research. 122:1501-1516
Rationale: In cardiomyocytes, Na V 1.5 and Kir2.1 channels interact dynamically as part of membrane bound macromolecular complexes. Objective: The objective of this study was to test whether Na V 1.5 and Kir2.1 preassemble during early forward traffi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07fd35e4da98c731c299754534847197
https://doi.org/10.1161/circresaha.117.311872
https://doi.org/10.1161/circresaha.117.311872
Publikováno v:
Neuropharmacology. 107:376-386
GLT-1 is the main glutamate transporter in the brain and undergoes trafficking processes that control its concentration on the cell surface thereby shaping glutamatergic neurotransmission. We have investigated how the traffic of GLT-1 is regulated by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6fc79e25ebfefa1d7bf1c7dbac63f5a
https://doi.org/10.1016/j.neuropharm.2016.03.042
https://doi.org/10.1016/j.neuropharm.2016.03.042
Autor:
Paloma Nieto-Marín, David Tinaquero, Marcos Matamoros, Raquel G. Utrilla, Marta Pérez-Hernández, Silvia Alfayate, José Jalife, Katherine Campbell, Teresa Crespo, Daniela Ponce-Balbuena, F. Javier Díez-Guerra, Eva Delpón, Ricardo Caballero, Andre Monteiro da Rocha, B. Cicero Willis, Juan Tamargo, Eric N. Jiménez-Vázquez, Todd J. Herron, Raquel de Andrés, Guadalupe Guerrero-Serna
Publikováno v:
JCI Insight. 3
Cardiac Nav1.5 and Kir2.1-2.3 channels generate Na (INa) and inward rectifier K (IK1) currents, respectively. The functional INa and IK1 interplay is reinforced by the positive and reciprocal modulation between Nav15 and Kir2.1/2.2 channels to streng
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf1bf7d4e53cc16e099494b339798458
https://doi.org/10.1172/jci.insight.96291
https://doi.org/10.1172/jci.insight.96291
Autor:
David Tinaquero, Sandra Sacristán, Juan Tamargo, Ricardo Caballero, Marta Pérez-Hernández, Paloma Nieto-Marín, Lorena Ondo, Raquel G. Utrilla, Marcos Matamoros, Eva Delpón, F. Javier Díez-Guerra, Raquel de Andrés, Silvia Alfayate
Publikováno v:
Frontiers in Physiology
Digital.CSIC. Repositorio Institucional del CSIC
instname
Repositorio Institucional de la Consejería de Sanidad de la Comunidad de Madrid
Consejería de Sanidad de la Comunidad de Madrid
Digital.CSIC. Repositorio Institucional del CSIC
instname
Repositorio Institucional de la Consejería de Sanidad de la Comunidad de Madrid
Consejería de Sanidad de la Comunidad de Madrid
Cardiac Kir2.1 and Nav1.5 channels generate the inward rectifier K+ (I) and the Na+ (I) currents, respectively. There is a mutual interplay between the ventricular I and I densities, because Nav1.5 and Kir2.1 channels exhibit positive reciprocal modu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98f9b3d01ad5ae8d79910d8b0a01c793
https://doi.org/10.3389/fphys.2017.00903
https://doi.org/10.3389/fphys.2017.00903
Publikováno v:
Experimental Gerontology. 47:198-201
We have studied the effect of aging and late onset caloric restriction (CR) on the expression of SIRT1 in hippocampus and cerebral cortex of the rat. Quantitative analysis showed that there is a significant reduction of SIRT1 protein levels in hippoc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9317dac6439266c0a11279a740d92465
https://doi.org/10.1016/j.exger.2011.11.010
https://doi.org/10.1016/j.exger.2011.11.010
Neurogranin, a link between calcium/calmodulin and protein kinase C signaling in synaptic plasticity
Autor:
F. Javier Díez-Guerra
Publikováno v:
IUBMB Life. 62:597-606
Neurogranin (Ng) (also named RC3, p17 or BICKS) is a small protein originally identified in rat brain and abundantly expressed in several telencephalic areas, such as the cerebral cortex, hippocampus, amygdala, and striatum. In neurons, it is found c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e4044a28ab0c9ef1cd4cb0805f26190
https://doi.org/10.1002/iub.357
https://doi.org/10.1002/iub.357
Publikováno v:
PLoS ONE, Vol 9, Iss 7, p e102526 (2014)
PLoS ONE
PLoS ONE
We developed genetically-encoded fluorescent sensors based on Forster Resonance Energy Transfer to monitor phosphatidic acid (PA) fluctuations in the plasma membrane using Spo20 as PA-binding motif. Basal PA levels and phospholipase D activity varied
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af0187fe3b286484c8081135c4d56360
http://europepmc.org/articles/PMC4099201?pdf=render
http://europepmc.org/articles/PMC4099201?pdf=render
Publikováno v:
Molecular and Cellular Neuroscience. 16:766-780
Cultured hippocampal neurons have been used to study GAP-43 phosphorylation and subcellular distribution. By immunofluorescence, GAP-43 was found associated with adherent membrane patches that remained attached to the substratum after in situ permeab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::560d6d9114e62ec70b423d953771ac93
https://doi.org/10.1006/mcne.2000.0915
https://doi.org/10.1006/mcne.2000.0915