Výsledky vyhledávání - "F X O'Sullivan"

Autor: J M Houri, F X O'Sullivan

Publikováno v: Current Opinion in Rheumatology. 7:201-205

Two new models for the study of rheumatoid arthritis have been established. SCID (severe combined immunodeficient) mice implanted with human synovial tissues and human HLA-DR4-CD4 transgenic mice represent novel and important approaches to the use of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b84defeb967447d1e6638917280024ef
https://doi.org/10.1097/00002281-199505000-00008

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Spontaneous elaboration of transforming growth factor beta suppresses host defense against bacterial infection in autoimmune MRL/lpr mice

Autor: W Waegell, F X O'Sullivan, J H Lowrance, T E Caver, Hattie D. Gresham

Publikováno v: The Journal of Experimental Medicine

Infection with gram-negative and gram-positive bacteria remains a leading cause of death in patients with systemic lupus erythematosis (SLE), even in the absence of immunosuppressive therapy. To elucidate the mechanisms that underly the increased ris

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https://doi.org/10.1084/jem.180.5.1693

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Scanning electron microscopic evaluation of the arthritis in MRL/lpr mice

Autor: F X, O'Sullivan, W J, Koopman, S, Gay

Publikováno v: Rheumatology International. 12:115-120

The articular surfaces of disarticulated knee joints from MRL/lpr and MRL/n mice, aged 4–33 weeks were examined by light microscopy (LM) and scanning electron microscopy (SEM). Light microscopy did not reliably predict SEM findings. Most of the abn

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29766dff7c51370c80b38fc0bfd62fda
https://doi.org/10.1007/bf00290266

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Defective neutrophil function in the autoimmune mouse strain MRL/lpr. Potential role of transforming growth factor-beta

Autor: H D Gresham, C J Ray, F X O'Sullivan

Publikováno v: The Journal of Immunology. 146:3911-3921

Patients with systemic autoimmune diseases such as SLE and rheumatoid arthritis have increased rates of morbidity and mortality caused by infection. Although this increased risk of infection has been primarily attributed to therapeutic immuno-suppres

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https://doi.org/10.4049/jimmunol.146.11.3911

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Mycoplasma infection and rheumatoid arthritis: analysis of their relationship using immunoblotting and an ultrasensitive polymerase chain reaction detection method

Autor: R W, Hoffman, F X, O'Sullivan, K R, Schafermeyer, T L, Moore, D, Roussell, R, Watson-McKown, M F, Kim, K S, Wise

Publikováno v: Arthritis and rheumatism. 40(7)

To examine the relationship between infection with Mycoplasma and the development of rheumatoid arthritis (RA) and juvenile rheumatoid arthritis (JRA).Immunoblotting of patient synovial fluid and sera on detergent-phase membrane protein extracts of v

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https://pubmed.ncbi.nlm.nih.gov/9550495

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The challenge of sensorineural hearing loss in rheumatoid arthritis

Autor: B, Mukerji, S A, Estrem, F X, O'Sullivan

Publikováno v: The Journal of rheumatology. 21(9)

Patients with rheumatoid arthritis are exposed to a variety of pharmacologic agents capable of causing sensorineural hearing loss. We describe such a patient who was eventually found to have an acoustic neuroma. The case illustrates the difficulty of

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https://pubmed.ncbi.nlm.nih.gov/7799362

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Pulmonary perivascular and interstitial inflammation in MRL/MpJ-lpr/lpr mice. III. Modulation by cyclophosphamide and sex hormones in 4- and 6-month-old animals

Autor: J S, Seggev, E V, Sunderrajan, T, Palomo, W N, McKenzie, S R, Braun, F X, O'Sullivan, S E, Walker

Publikováno v: Clinical immunology and immunopathology. 60(2)

Estradiol (E) abolished clearing of pulmonary inflammation in 2-month-old male MRL/MpJ-lpr/lpr (MRL/l) mice treated with cyclophosphamide (CY). To determine if this effect persisted in animals with advanced disease, we studied male and female MRL/l m

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https://pubmed.ncbi.nlm.nih.gov/2070571

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Defective neutrophil function in the autoimmune mouse strain MRL/lpr. Potential role of transforming growth factor-beta

Autor: H D, Gresham, C J, Ray, F X, O'Sullivan

Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 146(11)

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https://pubmed.ncbi.nlm.nih.gov/1674521

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Anti-histone antibodies in the serum of autoimmune MRL and NZB/NZW1 F1 mice

Autor: J E, Brick, S H, Ong, J M, Bathon, S E, Walker, F X, O'Sullivan, A G, DiBartolomeo

Publikováno v: Clinical immunology and immunopathology. 54(3)

Anti-histone antibodies have been reported in a number of human autoimmune diseases, most notably idiopathic and drug-induced lupus erythematosus. In the current study, anti-histone antibody activity was detected using ELISA and electroblotting techn

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https://pubmed.ncbi.nlm.nih.gov/2302840

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