Zobrazeno 1 - 10
of 6 295
pro vyhledávání: '"F Weber"'
Autor:
M Ingenwerth, T Brandenburg, D Führer-Sakel, M Goetz, F Weber, H Dralle, H-U Schildhaus, K W Schmid, S Theurer
Publikováno v:
Endocrine Connections, Vol 10, Iss 3, Pp 283-289 (2021)
Medullary thyroid carcinomas (MTC) are rare and aggressive neuroendocrine tumors of the thyroid. About 70% of MTC are sporadic; approximately 50% of those harbor somatic RET mutation. DLL3 is widely expressed in many neuroendocrine tumors and has bee
Externí odkaz:
https://doaj.org/article/2f79acdbc42e44feaf543f65b3623ea0
Autor:
Christina Kiel, Fabiola Biasella, Heidi Stöhr, Philipp Rating, Georg Spital, Ulrich Kellner, Karsten Hufendiek, Cord Huchzermeyer, Herbert Jaegle, Klaus Ruether, Bernhard H. F. Weber
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Inherited retinal dystrophies (IRDs) and inherited optic neuropathies (IONs) are characterized by distinct genetic causes and molecular mechanisms that can lead to varying degrees of visual impairment. The discovery of pathogenic variants in
Externí odkaz:
https://doaj.org/article/cf2e680a1c40414cb651066b9891dc27
Autor:
Maximilian Brunner, Martin Brandl, Axel Denz, Christian Krautz, Georg F. Weber, Robert Grützmann, Klaus Weber
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-9 (2024)
Abstract Restorative proctocolectomy with ileal pouch-anal anastomosis (IPAA) represents the standard treatment for therapy-refractory, malignant or complicated ulcerative colitis (UC) and can be performed as a 2-stage or 3-stage procedure. This stud
Externí odkaz:
https://doaj.org/article/bd5b30433ef54613b896f6e54f449ae2
Autor:
Frederik J. Hansen, Anke Mittelstädt, Finn-Niklas Clausen, Samuel Knoedler, Leonard Knoedler, Sebastian Klöckner, Isabelle Kuchenreuther, Johanne Mazurie, Lisa-Sophie Arnold, Anna Anthuber, Anne Jacobsen, Susanne Merkel, Nadine Weisel, Bettina Klösch, Alara Karabiber, Irem Tacyildiz, Franziska Czubayko, Helena Reitberger, Amr El Gendy, Maximilian Brunner, Christian Krautz, Kerstin Wolff, Sidonia Mihai, Clemens Neufert, Jürgen Siebler, Robert Grützmann, Georg F. Weber, Paul David
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal malignancies, presenting a persisting global health burden. Neutrophils have a double-edged role in tumor progression exhibiting both pro-tumor and anti-tumor functions. CD71,
Externí odkaz:
https://doaj.org/article/e79d863ff7694ca98076d9f8eae0ed3c
Autor:
Clara F. Weber, Valeria Kebets, Oualid Benkarim, Sara Lariviere, Yezhou Wang, Alexander Ngo, Hongxiu Jiang, Xiaoqian Chai, Bo-yong Park, Michael P. Milham, Adriana Di Martino, Sofie Valk, Seok-Jun Hong, Boris C. Bernhardt
Publikováno v:
Molecular Autism, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Objective Autism spectrum disorder (ASD) is a neurodevelopmental condition that is associated with atypical brain network organization, with prior work suggesting differential connectivity alterations with respect to functional connection le
Externí odkaz:
https://doaj.org/article/6fcd2afe371a4b99b8f9efebcbcb1749
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 23, Iss , Pp 2637-2647 (2024)
Molecular phylogenetic research has relied on the analysis of the coding sequences by genes or of the amino acid sequences by the encoded proteins. Enumerating the numbers of mismatches, being indicators of mutation, has been central to pertinent alg
Externí odkaz:
https://doaj.org/article/f417692da0974ff4b31e1e9584e8dcab
Autor:
S. Rahn, S. Skornitzke, C. Melzig, T. Reiner, W. Stiller, C. P. Heussel, H. U. Kauczor, T. F. Weber, T. D. Do
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract This study aimed to evaluate the impact of contrast media application on CT attenuation of the bone using a novel calcium-only imaging technique (VCa) from dual-layer spectral detector CT (DLCT), which enables CT-based bone mineral density m
Externí odkaz:
https://doaj.org/article/6a364e3dba47443995118ae33f204b9e
Publikováno v:
Arthritis Research & Therapy, Vol 26, Iss 1, Pp 1-14 (2024)
Abstract Background Hip and knee osteoarthritis (OA) are highly prevalent worldwide. The guidelines recommend physical activity and education as the core treatments for osteoarthritis. Digital health has the potential to engage people in physical act
Externí odkaz:
https://doaj.org/article/3629d94181c14c3188c3a546f2968241
Autor:
Jayshree Advani, Puja A. Mehta, Andrew R. Hamel, Sudeep Mehrotra, Christina Kiel, Tobias Strunz, Ximena Corso-Díaz, Madeline Kwicklis, Freekje van Asten, Rinki Ratnapriya, Emily Y. Chew, Dena G. Hernandez, Sandra R. Montezuma, Deborah A. Ferrington, Bernhard H. F. Weber, Ayellet V. Segrè, Anand Swaroop
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-20 (2024)
Abstract DNA methylation provides a crucial epigenetic mark linking genetic variations to environmental influence. We have analyzed array-based DNA methylation profiles of 160 human retinas with co-measured RNA-seq and >8 million genetic variants, un
Externí odkaz:
https://doaj.org/article/8d47fc27aef84583ace1428d94cd4bdd
Autor:
Gulimirerouzi Fnu, Georg F. Weber
Publikováno v:
Cancer Medicine, Vol 13, Iss 11, Pp n/a-n/a (2024)
Abstract Background We previously reported that metastases are generally characterized by a core program of gene expression that activates tissue remodeling/vascularization, alters ion homeostasis, induces the oxidative metabolism, and silences extra
Externí odkaz:
https://doaj.org/article/32d9d12e479746438df061ba89d8c0c3