Zobrazeno 1 - 10
of 14
pro vyhledávání: '"F W, Kari"'
Publikováno v:
In vitromolecular toxicology. 13(4)
Recent epidemiological evidence suggests that antioxidants may enhance carcinogenesis by promoting cellular proliferation and/or impeding programmed cell death. We examined the effect of N-acetyl-l-cysteine (NAC) on mitogenesis and apoptosis in splen
Publikováno v:
Environmental Health Perspectives
Caloric restriction has been shown to alter a broad range of immunological end points in both experimental animals and humans. The objective of this study was to investigate the effect of short-term moderate feed restriction (25% reduction) on allerg
Publikováno v:
The journal of nutrition, healthaging. 3(2)
This paper focuses on the role of insulin-like growth factor-1 (IGF-1) and its associated regulatory apparatus as a key endocrine, autocrine, and paracrine signalling system involved in mediating the anti-carcinogenic activity of dietary restriction.
Publikováno v:
Cancer research. 57(21)
Diet contributes to over one-third of cancer deaths in the Western world, yet the factors in the diet that influence cancer are not elucidated. A reduction in caloric intake dramatically slows cancer progression in rodents, and this may be a major co
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 280(2)
The antibiotic nitrofurantoin is transported against an electrochemical gradient into milk. A monolayer of CIT3 cells, a subline of the Comma 1D normal mouse mammary epithelial cell line, transports [14C]-nitrofurantoin against a concentration gradie
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 280(2)
Nitrofurantoin is a commonly used urinary tract antibiotic that has been found at high concentrations in human milk. In vivo studies in rats were carried out to determine the mechanism by which this drug crosses the mammary epithelium. Lactating rats
Publikováno v:
Journal of molecular endocrinology. 17(3)
Prolactin is a member of the growth hormone family and is required for the growth and terminal differentiation of the mammary gland. Ectopic production of this hormone has been reported in several species, including rat, sheep, goat and human mammary
Publikováno v:
Endocrine regulations. 27(4)
Early milk of rats contains high concentrations of many hormones and growth factors. Studies were undertaken to evaluate the physiological effects of early rat milk infranatant, insulin-like growth factors (IGFs) and epidermal growth factor (EGF) upo
Publikováno v:
Cancer research. 53(12)
A leukemia cell transplant model and both in situ and in vitro bioassays were used to assess the roles of endogenous factors in mediating diet restriction (DR)-induced inhibition of mononuclear cell leukemia (MNCL) in Fischer 344 rats. DR-treated mal
Publikováno v:
Critical reviews in toxicology. 22(3-4)
Glutaraldehyde, a low molecular weight aldehyde, has been investigated for toxicity in humans and animals. Examination of this dialdehyde was indicated from previous studies with other aldehydes in which carcinogenicity of formaldehyde and toxicity o