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Association of the common gamma-chain with the human IL-7 receptor is modulated by T cell activation
Publikováno v:
The Journal of Immunology. 158:5727-5735
IL-7 acts on both resting and activated T cells. The functional IL-7R is reported to consist of two subunits, the ligand binding IL-7R and the common gamma-chain (gamma c chain), where IL-7R:gamma c chain association is driven solely by ligand bindin
Publikováno v:
The Journal of biological chemistry. 274(11)
We have shown recently that interleukin (IL)-2 activates the mitogen-activated protein (MAP) kinase family members p38 (HOG1/stress-activated protein kinase II) and p54 (c-Jun N-terminal kinase/stress-activated protein kinase I). Furthermore, the p38
Association of the common gamma-chain with the human IL-7 receptor is modulated by T cell activation
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 158(12)
IL-7 acts on both resting and activated T cells. The functional IL-7R is reported to consist of two subunits, the ligand binding IL-7R and the common gamma-chain (gamma c chain), where IL-7R:gamma c chain association is driven solely by ligand bindin