Zobrazeno 1 - 10
of 533
pro vyhledávání: '"F V Chisari"'
Autor:
J Alexander, C Oseroff, J Sidney, P Wentworth, E Keogh, G Hermanson, F V Chisari, R T Kubo, H M Grey, A Sette
Publikováno v:
The Journal of Immunology. 159:4753-4761
Transgenic mice expressing chimeric human (alpha1 and alpha2 HLA-A11 domains) and murine (alpha3, transmembrane, and cytoplasmic H-2Kb domains) class I molecules were derived. These mice were used as a model system to study the immunogenicity of huma
Publikováno v:
The Journal of Experimental Medicine
Cytotoxic T lymphocytes (CTL) are thought to contribute to viral clearance and liver cell injury during hepatitis B virus (HBV) infection. Using a strategy involving the in vitro stimulation of peripheral blood mononuclear cells (PBMC) with HBV-deriv
Autor:
A Cerny, J G McHutchison, C Pasquinelli, M E Brown, M A Brothers, B Grabscheid, P Fowler, M Houghton, F V Chisari
Publikováno v:
Scopus-Elsevier
The HLA class I-restricted cytotoxic T lymphocyte (CTL) response is a major defense mechanism in viral infections. It has been suggested that the CTL response may contribute to viral clearance and liver cell injury during hepatitis C virus (HCV) infe
Autor:
Li, Jia1 (AUTHOR), Yuan, Jianlan2 (AUTHOR), Li, Hugang2 (AUTHOR), Guo, Jingyi2 (AUTHOR), Li, Mingjun3 (AUTHOR), Zhang, Tingbin3 (AUTHOR) Zhangtb@hebut.edu.cn, Liang, Xing‐Jie4,5,6 (AUTHOR), Fan, Haiming1,2 (AUTHOR), Liu, Xiaoli2,7,8 (AUTHOR) liuxiaoli0108@xjtu.edu.cn
Publikováno v:
Advanced Nanobiomed Research. Jun2024, Vol. 4 Issue 6, p1-17. 17p.
Autor:
B, Rehermann, F V, Chisari
Publikováno v:
Current topics in microbiology and immunology. 242
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 162(2)
The inverse relationship between peripheral blood CTL responsiveness to multiple hepatitis C virus (HCV) epitopes and viral titer in patients with persistent HCV infection suggests that enhancement of the CTL response might result in viral clearance.
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 161(11)
The molecular anatomy of an immunodominant, Ld restricted CTL epitope located between residues 28-39 in hepatitis B surface Ag was defined to explore the immunologic constraints on mutational escape from the CTL response during a viral infection. Usi
Publikováno v:
Cancer research. 57(16)
Chronic infection with hepatitis B virus (HBV) can cause liver cancer in humans. Transgenic mice expressing the major envelope protein of HBV, HBV surface antigen (HBsAg), represent an experimental model for some of the histopathological effects of i
Autor:
B D, Livingston, C, Crimi, H, Grey, G, Ishioka, F V, Chisari, J, Fikes, R W, Chesnut, A, Sette
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 159(3)
We have previously described the development of a lipopeptide-based vaccine, Theradigm-HBV, capable of inducing CTL responses in humans. This vaccine incorporates the HLA-A2.1-restricted CTL epitope hepatitis B core Ag 18-27, linked to the universal
Autor:
A, Kuhöber, H P, Pudollek, K, Reifenberg, F V, Chisari, H J, Schlicht, J, Reimann, R, Schirmbeck
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 156(10)
The serum Ab response and the class I-restricted CTL response of C57BL/6 (H-2b) mice to hepatitis B (pre)core Ag (HBcAg, HBeAg) was studied. Injection of HBcAg particles without adjuvants into mice efficiently primed serum Ab responses but not CTL re