Zobrazeno 1 - 10
of 664
pro vyhledávání: '"F Sinclair"'
Publikováno v:
Environmental Microbiome, Vol 19, Iss 1, Pp 1-11 (2024)
Abstract Background Rivers and streams are important components of the global carbon cycle and methane budget. However, our understanding of the microbial diversity and the metabolic pathways underpinning methylotrophic methane production in river se
Externí odkaz:
https://doaj.org/article/8f7944079ed249f89f85e9fd0ff73623
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-8 (2022)
Abstract Ferric derisomaltose (FDI; Monofer) is used in clinical practice to treat iron deficiency, but the safety and efficacy of FDI has not been robustly evaluated in a large real-world study. This retrospective, multicentre, audit-based, observat
Externí odkaz:
https://doaj.org/article/beddbac0d4374ede851ed242dfec2efd
Autor:
Jakub Chmelo, Alexander W. Phillips, Alastair Greystoke, Sarah J. Charman, Leah Avery, Kate Hallsworth, Jenny Welford, Matthew Cooper, Rhona C. F. Sinclair
Publikováno v:
Pilot and Feasibility Studies, Vol 8, Iss 1, Pp 1-10 (2022)
Abstract Background Treatment for locally advanced oesophagogastric adenocarcinoma involves neoadjuvant chemotherapy which has a negative impact on patient fitness. Using ‘prehabilitation’ to increase activity levels and fitness may affect physio
Externí odkaz:
https://doaj.org/article/057c6b302583472a9ec0ebd8c3d5c8df
Autor:
Sarah Charman, Matthew Cooper, Kate Hallsworth, Leah Avery, Alastair Greystoke, Jakub Chmelo, Rhona C F Sinclair, Jenny Welford, Alexander W Phillips
Publikováno v:
BMJ Open, Vol 12, Iss 9 (2022)
Objectives Preoperative exercise training can improve cardiorespiratory fitness before major surgery. However, little is known about what influences participation and adherence in high-risk patient groups. We identified barriers and facilitators to u
Externí odkaz:
https://doaj.org/article/e315518266a64a53b0856f186ccd7cba
Autor:
D. I. Saunders, R. C. F. Sinclair, B. Griffiths, E. Pugh, D. Harji, B. Salas, H. Reed, C. Scott
Publikováno v:
Perioperative Medicine, Vol 10, Iss 1, Pp 1-8 (2021)
Abstract Background Emergency laparotomy carries a significant risk profile around the time of surgery. This research aimed to establish the feasibility of recruitment to a study using validated scoring tools to assess complications after surgery; an
Externí odkaz:
https://doaj.org/article/0f51e2bd48cd4fb38a7f08e3ef38ed5b
Autor:
J. Chmelo, A. W. Phillips, A. Greystoke, S. J. Charman, L. Avery, K. Hallsworth, J. Welford, R. C. F. Sinclair
Publikováno v:
Pilot and Feasibility Studies, Vol 6, Iss 1, Pp 1-8 (2020)
Abstract Background Treatment of locally advanced oesophago-gastric adenocarcinoma usually entails neo-adjuvant chemotherapy (NAC) and surgery. Surgery is associated with high morbidity and mortality. Cardiopulmonary reserve of patients having major
Externí odkaz:
https://doaj.org/article/3616298259854b909de036f42753ce3a
Autor:
Maaike van Gerwen, Mathilda Alsen, Christine Little, Joshua Barlow, Leonard Naymagon, Douglas Tremblay, Catherine F. Sinclair, Eric Genden
Publikováno v:
Frontiers in Endocrinology, Vol 11 (2020)
Coronavirus diseases (COVID-19) is associated with high rates of morbidity and mortality and worse outcomes have been reported for various morbidities. The impact of pre-existing hypothyroidism on COVID-19 outcomes remains unknown. The aim of the pre
Externí odkaz:
https://doaj.org/article/901361cdb3f140bbbc8d5a2bc0297170
Publikováno v:
Current Opinion in Endocrinology, Diabetes & Obesity. 29:449-455
Radiofrequency ablation (RFA) for thyroid nodules confers tangible advantages over surgery, which include promising outcomes in the context of a minimally invasive procedure and the functional benefits of organ preservation. However, the ubiquity of
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Autor:
Christina Mayerhofer, Mina S Sedrak, Judith O Hopkins, Tianyu Li, Nabihah Tayob, Meredith G Faggen, Natalie F Sinclair, Wendy Y Chen, Heather A Parsons, Erica L Mayer, Paulina B Lange, Ameer S Basta, Adriana Perilla-Glen, Ruth I Lederman, Andrew R Wong, Abhay Tiwari, Sandra S McAllister, Elizabeth A Mittendorf, Christopher J Gibson, Harold J Burstein, Annette S Kim, Rachel A Freedman, Peter G Miller
Publikováno v:
JNCI: Journal of the National Cancer Institute.
Background The expansion of hematopoietic stem cells carrying recurrent somatic mutations, termed clonal hematopoiesis (CH), is common in elderly individuals and is associated with increased risk of myeloid malignancy and all-cause mortality. Though