Zobrazeno 1 - 10
of 98
pro vyhledávání: '"F Schweighoffer"'
Autor:
S M Cazaubon, F Schweighoffer, Pierre Olivier Couraud, Siegmund Fischer, Francisco Ramos-Morales, Arthur Donny Strosberg
Publikováno v:
Journal of Biological Chemistry. 269:24805-24809
While the mitogen-activated protein kinase (MAPK) pathway coupled to receptor tyrosine kinases has been largely clarified, little is known about MAPK activation mediated by heterotrimeric G protein-coupled receptors. In a previous study, it has been
Publikováno v:
Cell death and differentiation. 2(2)
Src homology type 2 (SH2) and type 3 (SH3) domains appear to have an important role in signal transduction pathways initiated by tyrosine kinases. SH2 domains allow proteins with signalling functions to interact with tyrosine kinases and tyrosine-pho
Autor:
F. Apiou, F. Schweighoffer, T. Ciora, I. Fath, Bruno Tocque, Bernard Dutrillaux, M.C. Chevallier-Multon
Publikováno v:
Nucleic acids research. 21(18)
Autor:
F, Schweighoffer, M, Faure, I, Fath, M C, Chevallier-Multon, F, Apiou, B, Dutrillaux, E, Sturani, M, Jacquet, B, Tocque
Publikováno v:
Oncogene. 8(6)
A critical step in the activation of cellular Ras is the release of bound GDP. Oligonucleotide primers derived from a mouse cDNA sequence homologous to the Saccharomyces cerevisiae CDC25 gene product were used to screen a human brain cDNA library. Th
Autor:
M C, Chevallier-Multon, F, Schweighoffer, I, Barlat, N, Baudouy, I, Fath, M, Duchesne, B, Tocqué
Publikováno v:
The Journal of biological chemistry. 268(15)
The best characterized yeast guanine nucleotide releasing factor is CDC25, which acts on RAS and thereby stimulates cAMP production in Saccharomyces cerevisiae. In order to determine if CDC25 could be a specific GDP-GTP releasing factor for the mamma
The Saccharomyces cerevisiae gene product SDC25 C-domain functions as an oncoprotein in NIH3T3 cells
Autor:
I, Barlat, F, Schweighoffer, M C, Chevallier-Multon, M, Duchesne, I, Fath, D, Landais, M, Jacquet, B, Tocque
Publikováno v:
Oncogene. 8(1)
Ras proteins in mammalian cells cycle between a GTP-bound 'on' state and a GDP-bound 'off' state. Activation of Ras p21 results from the dissociation of tightly bound GDP and the exchange of bound GDP for GTP. A guanine nucleotide exchange factor is
Autor:
I, Rey, F, Schweighoffer, I, Barlat, J, Camonis, E, Boy-Marcotte, R, Guilbaud, M, Jacquet, B, Tocque
Publikováno v:
Oncogene. 6(2)
The evidence presented here indicates that the domain containing the COOH-terminal part of the Saccharomyces cerevisiae SCD25 gene product (C-domain), which is homologous to the COOH-terminal part of CDC25 protein, can elicit activation of mammalian
Publikováno v:
Advances in second messenger and phosphoprotein research. 24
Autor:
F Schweighoffer, B Bocqué
Publikováno v:
médecine/sciences. 7:R24
L 'introduction de genes clones dans des cellules d'eucaryotes superieurs a permis d 'acceder a la fonction precoce de proteines impli quees dans des voies de signalisation cellulaire diverses. Les resultats observes par transfection transitoire da
Publikováno v:
Biochemical and Biophysical Research Communications. 134:1093-1100
3 specific cDNA clones for human aldolase A were isolated from a human muscle library. One of them was subcloned in M 13 phage, then used as a probe to investigate the patterns and the levels of aldolase A mRNA in various human tissues. Two mRNA spec