Zobrazeno 1 - 10
of 37
pro vyhledávání: '"F S, di Giovine"'
Publikováno v:
Genes & Immunity. 6:467-471
Biological activity of the IL-1 system depends on the balance between two proinflammatory proteins (IL-1alpha and IL-1beta) and the related anti-inflammatory protein, the IL-1 receptor antagonist (IL-1Ra). The genes for these proteins lie within 430
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::511e6a7887ed7b3080aabff02ec35239
https://doi.org/10.1038/sj.gene.6364228
https://doi.org/10.1038/sj.gene.6364228
Autor:
Martin J.H. Nicklin, Michael J. Cork, P. Dimitropoulou, Andrew J. G. McDonagh, F. S. Di Giovine, Rachid Tazi-Ahnini, J. M. Timms, Angela Cox, Andrew G. Messenger, Gordon W. Duff
Publikováno v:
European Journal of Immunogenetics. 29:25-30
Summary Alopecia areata is an inflammatory hair loss disease with a major genetic component. The presence of focal inflammatory lesions with perifollicular T-cell infiltrates reflects the importance of local cytokine production in the pathogenesis. I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::64663291a9769acab146533fd8bdeb4a
https://doi.org/10.1046/j.1365-2370.2002.00271.x
https://doi.org/10.1046/j.1365-2370.2002.00271.x
Autor:
V. Eaton, A. Pacilli, Gordon W. Duff, Ian P. Hall, Moira K. B. Whyte, M. Whidborne, Colin D. Bingle, R. Hubbard, A. Facchini, R. Meliconi, M. Fabbri, I. Johnston, J. M. Timms, F. S. Di Giovine, J. Britton
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 162:755-758
Fibrosing alveolitis (FA) is characterized by persistent inflammation and elevated production of tumor necrosis factor-alpha (TNF-alpha), interleukin-1 beta (IL-1beta), and interleukin-1 receptor antagonist (IL-1ra) in the lung. Single base variation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14fa120f2b1e0c9ed614bb619af1d73c
https://doi.org/10.1164/ajrccm.162.2.9909053
https://doi.org/10.1164/ajrccm.162.2.9909053
Publikováno v:
Rheumatology. 34:454-460
The inflammatory cytokines interleukin 1 beta (IL-1 beta) interleukin 6 (IL-6), tumour necrosis factor alpha (TNF alpha) and the anti-inflammatory peptide--the interleukin 1 (IL-1) receptor antagonist--were measured in the plasma of children with juv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cabcbe8a38c192a8342fe5c57f51b3e5
https://doi.org/10.1093/rheumatology/34.5.454
https://doi.org/10.1093/rheumatology/34.5.454
Publikováno v:
Journal of Clinical Investigation. 87:1375-1381
Crystals of monosodium urate (MSU) provide a dose-dependent stimulus for the production by human blood monocytes of tumor necrosis factor (TNF), a cytokine with proinflammatory properties; TNF activity was inhibited selectively by monoclonal antibody
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::141c0dec7a19c3650cefce60e65bada9
https://doi.org/10.1172/jci115142
https://doi.org/10.1172/jci115142
Publikováno v:
Rheumatology International. 9:259-264
There are two forms of the cytokine interleukin 1 (IL1), produced by two distinct genes encoding a neutral (IL1 beta) and an acidic (IL1 alpha) peptide. They have powerful pro-inflammatory, immunopotentiating, catabolic and arthritogenic properties i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c442956a7212f59136b36608a3f3f28
https://doi.org/10.1007/bf00541321
https://doi.org/10.1007/bf00541321
Autor:
R, Tazi-Ahnini, A, Cox, A J G, McDonagh, M J H, Nicklin, F S, di Giovine, J M, Timms, A G, Messenger, P, Dimitropoulou, G W, Duff, M J, Cork
Publikováno v:
European journal of immunogenetics : official journal of the British Society for Histocompatibility and Immunogenetics. 29(1)
Alopecia areata is an inflammatory hair loss disease with a major genetic component. The presence of focal inflammatory lesions with perifollicular T-cell infiltrates reflects the importance of local cytokine production in the pathogenesis. In additi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fe21c9f8d70aa327f2dc2321a9029a74
https://pubmed.ncbi.nlm.nih.gov/11841485
https://pubmed.ncbi.nlm.nih.gov/11841485
Autor:
John B. Mee, Gordon W. Duff, F. S. Di Giovine, Alan J Lobo, Nicola J. Camp, S. Jones, M J Carter
Publikováno v:
Gut. 48(4)
BACKGROUND AND AIMS—An association between the allele 2 of the interleukin 1 receptor antagonist gene variable number tandem repeats polymorphism in intron 2 and ulcerative colitis was first reported in 1994. Subsequent studies in Caucasian Norther
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be89b7d2de503db4328fa08aff9e5532
https://pubmed.ncbi.nlm.nih.gov/11247888
https://pubmed.ncbi.nlm.nih.gov/11247888
Publikováno v:
Genes and immunity. 2(4)
The balance between interleukin-1 (IL-1) and its competitive antagonist IL-1 receptor antagonist (IL-1Ra) may contribute to the pathogenesis of rheumatoid arthritis (RA). We analysed the frequency of different alleles in the IL-1B gene (at -511 and a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::056641d823b8bd5327207a9aea48026a
https://pubmed.ncbi.nlm.nih.gov/11477478
https://pubmed.ncbi.nlm.nih.gov/11477478
Autor:
Gordon W. Duff, Edouard Vannier, Pierre Miossec, N. Buchs, F. S. Di Giovine, Tania Silvestri, Martine Chabaud
Publikováno v:
Rheumatology (Oxford, England). 39(10)
Objective. To evaluate the occurrence of variants of the interleukin 4 (IL-4) and IL-4 receptor (IL-4R) genes in patients with rheumatoid arthritis (RA) and their possible contribution to joint destruction. Methods. Allelic frequencies for polymorphi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd29af224fb2f9956d52ff645eb384fa
https://pubmed.ncbi.nlm.nih.gov/11035134
https://pubmed.ncbi.nlm.nih.gov/11035134