Zobrazeno 1 - 10
of 28
pro vyhledávání: '"F S, Zarudiĭ"'
Autor:
Iu V, Vakhitova, E I, Antipina, R S, Yamidanov, R Iu, Khisamutdinova, F S, Zarudiĭ, N Zh, Baschenko, V A, Dokichev, Iu V, Tomilov, O M, Nefedov
Publikováno v:
Bioorganicheskaia khimiia. 37(6)
The goal of the current work is to study the molecular mechanisms underlay the action of 5- amino-exo-3-azatricyclo[5.2.1.0(2,6)]decan-4-one (P-11) with combined antiarrhythmic, nootropic, anti-inflammatory and anaesthetic activities. The aconitine-i
Autor:
S F, Gabdrakhmanova, N S, Makara, T V, Sapozhnikova, N Zh, Baschenko, V S, Nazarov, F S, Zarudiĭ
Publikováno v:
Eksperimental'naia i klinicheskaia farmakologiia. 71(2)
11-Deoxymisoprostol demonstrates antiaggregant properties with respect to the adrenalin-, collagen-, and ADP-induced aggregation of thrombocytes, which is manifested by a decrease in the rate of blood platelet agglutination and their secretion, and b
Autor:
T A, Sapozhnikova, F S, Zarudiĭ, N Zh, Baschenko, N S, Makara, R Iu, Khisamutdinova, S F, Gabdrakhmanova, N A, Ivanova, V S, Nazarov
Publikováno v:
Eksperimental'naia i klinicheskaia farmakologiia. 70(4)
2-Demethoxycarbonyl-2-ethoxycarbonyl-11-deoxymisoprostol (11-DMP) produces antioxidant effect on the models of toxic hepatitis induced by paracetamol and carbon tetrachloride. The drug normalizes the lipid peroxidation (LPO) prosess in rat liver of t
Autor:
V R, Khaĭrullina, A D, Mukhametov, L A, Tiurina, G G, Garifullina, A Ia, Gerchikov, F S, Zarudiĭ
Publikováno v:
Biomeditsinskaia khimiia. 53(3)
Using the computer system SARD-21 (Structure Activity RelationshipDesign) the structural features typical for high- and low- effective nonsteroid anti-inflammatory drugs (NSAIDs) were analyzed. This information has been used for the model for predict
Autor:
R Iu, Khisatmutdinova, N Zh, Baschenko, F S, Zarudiĭ, S F, Gabdrakhmanova, N S, Makara, T A, Sapozhnikova
Publikováno v:
Eksperimental'naia i klinicheskaia farmakologiia. 69(3)
The antiarrhythmic activity of allapinine and glialin (a complex of allapinin and glycyrrhizic acid) was studied on models of arrhythmias induced in rats and guinea pigs by intravenous administration of calcium chloride, aconitine, barium chloride, a
Autor:
L T, Karachurina, T A, Sapozhnikova, F S, Zarudiĭ, O B, Flekhter, L R, Nigmatullina, F Z, Galin
Publikováno v:
Eksperimental'naia i klinicheskaia farmakologiia. 66(4)
The results of pharmacological tests showed that betulin bishemiphthalate possesses hepatoprotector, antioxidant, and immunotropic properties. Administered in combination with hydroxymethyluracil, that betulin bishemiphthalate prevented the loss of e
Autor:
T A, Sapozhnikova, F S, Zarudiĭ, L T, Karachurina, N S, Makara, R Iu, Khisamutdinova, A M, Shaĭnurova, N A, Ivanova, M S, Miftakhov
Publikováno v:
Eksperimental'naia i klinicheskaia farmakologiia. 66(1)
11-Deoxymisoprostol showed gastroprotector activity on the acute models of ulcers induced by acetylsalicylic acid and ethanol and produced curative effect on the chronic ulceration model induced by acetic acid. The positive effect is manifested by a
Autor:
O B, Flekhter, L T, Karachurina, L R, Nigmatullina, T A, Sapozhnikova, L A, Baltina, F S, Zarudiĭ, F Z, Galin, L V, Spirikhin, G A, Tolstikov, O A, Pliasunova
Publikováno v:
Bioorganicheskaia khimiia. 28(6)
The assignment of NMR resonances of lupane triterpenoids was refined by the example of 3,28-dinicotinoylbetulin, obtained by acylation of betulin. Hepatoprotective, untiulcer, antiinflammatory, reparative, and anti-HIV activities were found for the c
Autor:
O B, Flekhter, L T, Karachurina, V V, Poroĭkov, L R, Nigmatullina, L A, Baltina, F S, Zarudiĭ, V A, Davydova, L V, Spirikhin, I P, Baĭkova, F Z, Galin, G A, Tolstikov
Publikováno v:
Bioorganicheskaia khimiia. 26(3)
Hemisuccinates, hemiphthalates, acetylsalicylates, cinnamates, and p-methoxycinnamates of lupeol, betulin, and 3-O-acetylbetulin were synthesized via interaction with corresponding acid anhydrides or acid chlorides. A number of betulin esters in posi
Publikováno v:
Eksperimental'naia i klinicheskaia farmakologiia. 61(5)
In experimental study of antiulcerative activity of dibunol on various models of gastric ulcers in rats the drug caused a marked antiulcerative effect in all of them, reduced the incidence of ulcer formation, and shortened the time of ulcer healing.