Zobrazeno 1 - 10
of 163
pro vyhledávání: '"F S, Markland"'
Autor:
S. D. Gangolli
Publikováno v:
Journal of Applied Toxicology. 9:69-69
Publikováno v:
Handbook of Venoms and Toxins of Reptiles ISBN: 9780429186394
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5e7a25dc200539cc87d8281846f8c29c
https://doi.org/10.1201/9781420008661-12
https://doi.org/10.1201/9781420008661-12
Autor:
S. Swenson, F. S. Markland
Publikováno v:
Toxin Reviews. 25:351-378
Publikováno v:
Journal of Liquid Chromatography. 16:2189-2201
Prior studies have indicated that highly purified samples of natural fibrolase. a fibrinolytic metalloproteinase from southern copperhead snake venom, contains two isoforms. The isoelectric points of these isoforms differ by 0.01 to 0.03 pH units. In
Publikováno v:
Current drug targets. Cardiovascularhaematological disorders. 4(4)
Snake venoms contain a number of serine and metalloproteinases, included among these are the fibrinolytic metalloproteinases. When the fibrinolytic enzymes were first isolated from viper venoms it was postulated that there may be a clinical applicati
Contortrostatin, a dimeric disintegrin from Agkistrodon contortrix contortrix, inhibits angiogenesis
Publikováno v:
Angiogenesis. 3(3)
Contortrostatin, a 13.5 kDa disulfide-linked homodimeric polypeptide possessing an Arg-Gly-Asp sequence, was isolated from venom of the southern copperhead snake. Daily injection of contortrostatin into the primary tumor of human breast cancer MDA-MB
Publikováno v:
Anticancer research. 20(6B)
The snake venom disintegrin contortrostatin has been shown to bind to integrins alpha IIb beta 3, alpha v beta 3, alpha v beta 5, and alpha 5 beta 1 and to exert an anti-tumor activity in vitro and in vivo. The cytokine TNF-alpha has been demonstrate
Publikováno v:
Breast cancer research and treatment. 61(3)
We report the results of a multidisciplinary study on the inhibitory effect of a snake venom disintegrin, contortrostatin, a 13.5 kDa homodimeric protein isolated from Agkistrodon contortrix contortrix (southern copperhead) venom, on breast cancer pr
Publikováno v:
Journal of cellular biochemistry. 79(1)
Contortrostatin is a homodimeric disintegrin that inhibits platelet aggregation and cell adhesion to extracellular matrix proteins by blocking integrins. The effect of contortrostatin on integrin-mediated signaling in tumor cells was investigated by
Autor:
F S, Markland
Publikováno v:
Thrombosis and haemostasis. 79(3)