Zobrazeno 1 - 10
of 12
pro vyhledávání: '"F S, Leach"'
Publikováno v:
Actas urologicas espanolas. 29(2)
Correction of misincorporated nucleotides during DNA replication (mismatch repair) distinguishes histologically similar cancers with distinct biological and clinical behavior. We investigated expression of two mismatch repair genes in testis cancer t
Publikováno v:
The Journal of urology. 164(5)
Mismatch repair genes are responsible for the coordinated correction of misincorporated nucleotides formed during DNA replication. Inactivating and inherited mutations in the prototypic mismatch repair gene hMSH2 have been described in a cancer predi
Publikováno v:
Cancer. 88(10)
The human mismatch repair (MMR) gene hMSH2 (human mutS homolog-2) is a DNA repair gene that has been reported to be mutated in 40% of hereditary nonpolyposis colon cancer (HNPCC) kindreds and a small percentage of sporadic tumors. HNPCC is a cancer p
Publikováno v:
Urology. 49(2)
Nephrectomy and creation of a cutaneous ureterovesicostomy for intermittent catheterization of the bladder traditionally requires two surgical procedures performed through separate incisions. Herein we report completion of these procedures using a tr
Autor:
S, Thiagalingam, N A, Lisitsyn, M, Hamaguchi, M H, Wigler, J K, Willson, S D, Markowitz, F S, Leach, K W, Kinzler, B, Vogelstein
Publikováno v:
Cancer research. 56(13)
A variety of studies suggests that tumor suppressor loci on chromosome 3p are important in various forms of human neoplasia. Recently, a chromosome 3p14.2 gene called FHIT was discovered and proposed as a candidate tumor suppressor gene in colorectal
Autor:
F S, Leach, K, Polyak, M, Burrell, K A, Johnson, D, Hill, M G, Dunlop, A H, Wyllie, P, Peltomaki, A, de la Chapelle, S R, Hamilton, K W, Kinzler, B, Vogelstein
Publikováno v:
Cancer research. 56(2)
Hereditary nonpolyposis colorectal cancer is caused by inherited mutations of mismatch repair genes. We developed monoclonal antibodies to the prototype human mismatch repair gene hMSH2 and used them to detect an immunoreactive protein of M(r) 100,00
Autor:
H, Katabuchi, B, van Rees, A R, Lambers, B M, Ronnett, M S, Blazes, F S, Leach, K R, Cho, L, Hedrick
Publikováno v:
Cancer research. 55(23)
Endometrial carcinoma is the second most common tumor type in women with hereditary nonpolyposis colorectal carcinoma. Microsatellite instability (MI) has been observed in the inherited (hereditary nonpolyposis colorectal carcinoma-associated) form o
Autor:
F S, Leach, T, Tokino, P, Meltzer, M, Burrell, J D, Oliner, S, Smith, D E, Hill, D, Sidransky, K W, Kinzler, B, Vogelstein
Publikováno v:
Cancer research. 53
The p53 and MDM2 genes were analyzed in 24 human soft tissue sarcomas (11 malignant fibrous histiocytomas and 13 liposarcomas). Alterations of p53, consisting of point mutations, deletions, or overexpression, were detected in one-third (8 of 24) of t
Publikováno v:
Journal of virology. 57(3)
We investigated the control of human cytomegalovirus (CMV) late (gamma)-gene expression in human fibroblast cells. Transcriptional activity of two gamma genes, encoding ICP27, a structural component (matrix or tegument) of virions, and ICP36, a major
Autor:
F S Leach, Edward S. Mocarski
We have investigated the transcriptional regulation of the human cytomegalovirus gamma gene encoding the ICP36 family (p52, the major late DNA-binding protein). The ICP36 transcription unit initiates at three distinct sites which are separated by app
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5b2b5dcbfe7398db3592f0f86824f99
https://europepmc.org/articles/PMC248444/
https://europepmc.org/articles/PMC248444/