Zobrazeno 1 - 10
of 89
pro vyhledávání: '"F S, Laroux"'
Autor:
G Parkes, R Ungaro, S Danese, M Abreu, E Arenson, W Zhou, D Ilo, F S Laroux, H Deng, Y Sanchez Gonzalez, L Peyrin-Biroulet
Publikováno v:
Journal of Crohn's and Colitis. 16:i476-i477
Background Establishing mucosal healing (MH) as a treatment goal for ulcerative colitis (UC) requires evidence of improvement in both endoscopic and histologic assessments of the intestinal mucosa and long-term sequalae. Currently, guidelines on how
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5a7c8a3b6ff16d9fd2c8ff86cd139b42
https://doi.org/10.1093/ecco-jcc/jjab232.648
https://doi.org/10.1093/ecco-jcc/jjab232.648
Autor:
L Peyrin-Biroulet, C Siegel, S Tanida, P Bossuyt, E Torres, M Dubinsky, F Baert, W Zhou, J Klaff, S Berg, F S Laroux, Y Sanchez Gonzalez, X Yao, Q Zhou, W Reinisch
Publikováno v:
Journal of Crohn's and Colitis. 16:i477-i478
Background Upadacitinib (UPA), an oral selective and reversible JAK inhibitor, demonstrated significantly greater efficacy compared to placebo (PBO) as treatment for moderate to severe ulcerative colitis (UC), in phase 3 induction (U-ACHIEVE and U-AC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::72417dfd7c162285cafbe184d5aa9100
https://doi.org/10.1093/ecco-jcc/jjab232.649
https://doi.org/10.1093/ecco-jcc/jjab232.649
Autor:
Ian N. Hines, Sulaiman Bharwani, Shigeyuki Kawachi, Kevin P. Pavlick, Hirohisa Harada, Matthew B. Grisham, Jason M. Hoffman, F. S. Laroux
Publikováno v:
Acta Physiologica Scandinavica. 173:113-118
A number of laboratories have sought to elucidate the role of nitric oxide (NO) in both acute and chronic inflammatory diseases. It is now well appreciated that NO can influence many aspects of the inflammatory cascade ranging from its own expression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::43ade5b01d3efb9c13424d892dd2542d
https://doi.org/10.1046/j.1365-201x.2001.00891.x
https://doi.org/10.1046/j.1365-201x.2001.00891.x
Publikováno v:
Biochemical and Biophysical Research Communications. 244:525-530
The nitric oxide (NO)-dependent S-nitrosation of thiols to generate S-nitrosothiols has been proposed as an important pathway for the metabolism of NO in vivo. Although it has been suggested that these S-nitrosated compounds are resistant to decompos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::944ff4a4708e15ff19d7a17cc9eb70ae
https://doi.org/10.1006/bbrc.1998.8227
https://doi.org/10.1006/bbrc.1998.8227
Autor:
M Symonds, D Kimpel, Christopher G. Kevil, Davis Cp, Jonathan S. Alexander, T. H. Jackson, O Blaschuk, T Dayton, Naotsuka Okayama, S M Berney, S Hill, F S Laroux
Publikováno v:
Inflammation. 22:573-582
T-lymphocytes routinely traffic from the lymphoid and vascular compartments to the tissues during immune surveillance and inflammatory responses. This egress occurs without compromising endothelial barrier, which is maintained by tight junctions (zon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8ed7f1f680a9fb2121d6f7e8e48f0fc4
https://doi.org/10.1023/a:1022310429868
https://doi.org/10.1023/a:1022310429868
Autor:
Christopher G. Kevil, Theodore J. Kalogeris, Matthew B. Grisham, L Walsh, F S Laroux, Jonathan S. Alexander
Publikováno v:
Biochemical and Biophysical Research Communications. 238:277-279
We report a simple, sensitive and rapid method for performing Northern blotting analysis which avoids the use of toxic chemicals such as formamide and glyoxal. This technique allows sensitive detection of various transcripts from total RNA samples va
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a2341265fcbec08ca45a505dcae6208
https://doi.org/10.1006/bbrc.1997.7284
https://doi.org/10.1006/bbrc.1997.7284
Autor:
Theodore J. Kalogeris, Elaine M. Conner, Matthew B. Grisham, Adam S. Cockrell, John W. Fuseler, F S Laroux, S. Brand, Laura Gray
Publikováno v:
Expert opinion on investigational drugs. 8(9)
Nuclear factor kappaB (NF-kappaB) is an ubiquitous transcription factor and pleiotropic regulator of numerous inflammatory and immune responses. Once activated, NF-kappaB translocates from the cytosol to the nucleus of the cell, where it binds to its
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::063ab6e5f26f137274739af757632c60
https://pubmed.ncbi.nlm.nih.gov/15992157
https://pubmed.ncbi.nlm.nih.gov/15992157
Autor:
C F, Krieglstein, W H, Cerwinka, F S, Laroux, J W, Salter, J M, Russell, G, Schuermann, M B, Grisham, C R, Ross, D N, Granger
Publikováno v:
The Journal of Experimental Medicine
Several reports have implicated reactive oxygen and nitrogen metabolites (RONS) in the initiation and/or progression of inflammatory bowel diseases (IBDs). We have investigated the role of three key RONS-metabolizing enzymes (inducible nitric oxide s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8eedcfe146524de0a160972ce54d937f
https://pubmed.ncbi.nlm.nih.gov/11696587
https://pubmed.ncbi.nlm.nih.gov/11696587
Autor:
F S, Laroux, K P, Pavlick, I N, Hines, S, Kawachi, H, Harada, S, Bharwani, J M, Hoffman, M B, Grisham
Publikováno v:
Acta physiologica Scandinavica. 173(1)
A number of laboratories have sought to elucidate the role of nitric oxide (NO) in both acute and chronic inflammatory diseases. It is now well appreciated that NO can influence many aspects of the inflammatory cascade ranging from its own expression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5ded5d84678fa9c512370c2c5f9d6a3c
https://pubmed.ncbi.nlm.nih.gov/11678733
https://pubmed.ncbi.nlm.nih.gov/11678733
Autor:
F S, Laroux, M B, Grisham
Publikováno v:
Microcirculation (New York, N.Y. : 1994). 8(5)
Inflammatory bowel disease (IBD) is a chronic inflammatory condition of the intestine and/or colon of unknown etiology in which patients suffer from severe diarrhea, rectal bleeding, abdominal pain, fever, and weight loss. Active episodes of IBD are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7efc5c0354db339dc7e7a56474499f8b
https://pubmed.ncbi.nlm.nih.gov/11687942
https://pubmed.ncbi.nlm.nih.gov/11687942