Zobrazeno 1 - 10
of 15
pro vyhledávání: '"F Russell, Westwood"'
Autor:
Richard Haworth, Michael Mirsky, Gerald G. Long, Justin D. Vidal, Ute Bach, Anke Heuser, Ronald A. Herbert, Karen Regan, Midori Yoshida, F. Russell Westwood, Johannes H. Harleman, George L. Foley, Darlene Dixon, Eric Van Esch, Roger Alison, Karyn Colman
Publikováno v:
Journal of Toxicologic Pathology
The INHAND (International Harmonization of Nomenclature and Diagnostic Criteria for Lesions in Rats and Mice) Project (www.toxpath.org/inhand.asp) is a joint initiative of the Societies of Toxicological Pathology from Europe (ESTP), Great Britain (BS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14316589e64325c4d1fddaf85284ec7f
http://europepmc.org/articles/PMC4253081
http://europepmc.org/articles/PMC4253081
Autor:
Dumitru Constantin-Teodosiu, Elizabeth A. Martin, Wendy Davies, F. Russell Westwood, Philip Glaves, Paul L. Greenhaff, Joanne Mallinson, James E. Sidaway
Publikováno v:
The Journal of Physiology. 590:6389-6402
We previously reported that statin myopathy is associated with impaired carbohydrate (CHO) oxidation in fast-twitch rodent skeletal muscle, which we hypothesised occurred as a result of forkhead box protein O1 (FOXO1) mediated upregulation of pyruvat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e39139e2abc38bb2d7bd6271b842d1d8
https://doi.org/10.1113/jphysiol.2012.238022
https://doi.org/10.1113/jphysiol.2012.238022
Autor:
Paul L. Greenhaff, James E. Sidaway, Joanne Mallinson, Dumitru Constantin-Teodosiu, F. Russell Westwood
Publikováno v:
The Journal of Physiology. 587:219-230
Statins are used clinically for cholesterol reduction, but statin therapy is associated with myopathic changes through a poorly defined mechanism. We used an in vivo model of statin myopathy to determine whether statins up-regulate genes associated w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e2b1f7fc33bf94f6b7198847492a9005
https://doi.org/10.1113/jphysiol.2008.164699
https://doi.org/10.1113/jphysiol.2008.164699
Publikováno v:
Toxicologic Pathology. 36:345-352
Rosuvastatin is a relatively new member of the statin family (HMG-CoA reductase inhibitors), with superior lipid-lowering effects and a pattern of clinical side effects, including a low incidence of myopathy, similar to other widely prescribed statin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4efb5e67522396c9f0c51fb67c0f103c
https://doi.org/10.1177/0192623307311412
https://doi.org/10.1177/0192623307311412
Autor:
Stefan P. Ivanavicius, Adrian D. Ball, F. Russell Westwood, Chris G. Heapy, Fraser Murray, Simon Read
Publikováno v:
Pain. 128:272-282
Intra-articular injection of mono-iodoacetate (MIA) in the rat knee joint induces a histopathology with similarities to osteoarthritis (OA). Typically, a synovitis (days 1-3) is observed followed by thinning of articular cartilage and subsequent lesi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a6f73e31b50cdf1628571a832146cd9
https://doi.org/10.1016/j.pain.2006.12.022
https://doi.org/10.1016/j.pain.2006.12.022
Publikováno v:
Toxicologic Pathology. 33:246-257
Simvastatin and cerivastatin have been used to investigate the development of statin-induced muscle necrosis in the rat. This was similar for both statins and was treatment-duration dependent, only occurring after 10 days had elapsed even if the dose
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::603599a58eb130fd3d683d628e66161a
https://doi.org/10.1080/01926230590908213
https://doi.org/10.1080/01926230590908213
Publikováno v:
International Journal of Radiation Oncology*Biology*Physics. 54:1497-1502
The aim of these studies was to evaluate factors that contribute to the selectivity of the novel vascular targeting agent ZD6126.Human umbilical vein endothelial cells (HUVECs) were treated with ZD6126 phenol, and effects on morphology, detachment, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2e9ee2bfde2c0e9fd623b36dd65749c
https://doi.org/10.1016/s0360-3016(02)03922-6
https://doi.org/10.1016/s0360-3016(02)03922-6
Publikováno v:
Toxicologic Pathology. 23:373-384
ICI 185,282 is a specific thromboxane receptor antagonist developed by ZENECA Pharmaceuticals for potential use in the treatment of inflammatory disease. During safety evaluation in dogs, multifocal granulomatous infiltrates occurred in multiple orga
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8dab76371a5dbecd6c79c8ff62ae5fdd
https://doi.org/10.1177/019262339502300314
https://doi.org/10.1177/019262339502300314
Autor:
Joanne E, Mallinson, Dumitru, Constantin-Teodosiu, Philip D, Glaves, Elizabeth A, Martin, Wendy J, Davies, F Russell, Westwood, James E, Sidaway, Paul L, Greenhaff
Publikováno v:
The Journal of physiology. 590(24)
We previously reported that statin myopathy is associated with impaired carbohydrate (CHO) oxidation in fast-twitch rodent skeletal muscle, which we hypothesised occurred as a result of forkhead box protein O1 (FOXO1) mediated upregulation of pyruvat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::438706f0055efc2724744e119c821a42
https://pubmed.ncbi.nlm.nih.gov/23045346
https://pubmed.ncbi.nlm.nih.gov/23045346
Autor:
Joanne E, Mallinson, Dumitru, Constantin-Teodosiu, James, Sidaway, F Russell, Westwood, Paul L, Greenhaff
Statins are used clinically for cholesterol reduction, but statin therapy is associated with myopathic changes through a poorly defined mechanism. We used an in vivo model of statin myopathy to determine whether statins up-regulate genes associated w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::b224360360bcdb16bf527e1b9ae02216
https://europepmc.org/articles/PMC2670035/
https://europepmc.org/articles/PMC2670035/
