Zobrazeno 1 - 10
of 61
pro vyhledávání: '"F Rob Jackson"'
Publikováno v:
PLoS Genetics, Vol 17, Iss 9, p e1009790 (2021)
Recent studies have demonstrated that astrocytes cooperate with neurons of the brain to mediate circadian control of many rhythmic processes including locomotor activity and sleep. Transcriptional profiling studies have described the overall rhythmic
Externí odkaz:
https://doaj.org/article/907c60a3d5454f08ab1c50de388699c3
Publikováno v:
PLoS Genetics, Vol 10, Iss 9, p e1004536 (2014)
The Drosophila homolog of Casein Kinase I δ/ε, DOUBLETIME (DBT), is required for Wnt, Hedgehog, Fat and Hippo signaling as well as circadian clock function. Extensive studies have established a critical role of DBT in circadian period determination
Externí odkaz:
https://doaj.org/article/a16600ce091f42cc8b366dea2be46b08
Publikováno v:
PLoS Biology, Vol 11, Iss 11, p e1001703 (2013)
Genome-wide studies of circadian transcription or mRNA translation have been hindered by the presence of heterogeneous cell populations in complex tissues such as the nervous system. We describe here the use of a Drosophila cell-specific translationa
Externí odkaz:
https://doaj.org/article/e7961a1a840d4ed085f50e35befa3edf
Publikováno v:
PLoS ONE, Vol 2, Iss 10, p e1107 (2007)
Despite substantial progress in defining central components of the circadian pacemaker, the output pathways coupling the clock to rhythmic physiological events remain elusive. We previously showed that LARK is a Drosophila RNA-binding protein which f
Externí odkaz:
https://doaj.org/article/a3c87fb3e941442a91569b29e476db46
Publikováno v:
iScience, Vol 27, Iss 3, Pp 109106- (2024)
Summary: We show that a sleep-regulating, Ig-domain protein (NKT) is secreted from Drosophila mushroom body (MB) α′/β′ neurons to act locally on other MB cell types. Pan-neuronal or broad MB expression of membrane-tethered NKT (tNkt) protein re
Externí odkaz:
https://doaj.org/article/40c0295215d0447aa0eecfedda2e6121
Autor:
Nathan S Blow, Robert N Salomon, Kerry Garrity, Isabelle Reveillaud, Alan Kopin, F Rob Jackson, Paula I Watnick
Publikováno v:
PLoS Pathogens, Vol 1, Iss 1, p e8 (2005)
Cholera, the pandemic diarrheal disease caused by the gram-negative bacterium Vibrio cholerae, continues to be a major public health challenge in the developing world. Cholera toxin, which is responsible for the voluminous stools of cholera, causes c
Externí odkaz:
https://doaj.org/article/7ee71de66f654dd89351dff91a48f565
Publikováno v:
WIREs Developmental Biology. 9
Glial astrocytes of vertebrates and invertebrates are important modulators of nervous system development, physiology, and behavior. In all species examined, astrocytes of the adult brain contain conserved circadian clocks, and multiple studies have s
Comparison of Larval and Adult Drosophila Astrocytes Reveals Stage-Specific Gene Expression Profiles
Publikováno v:
G3: Genes|Genomes|Genetics
The analysis of adult astrocyte glial cells has revealed a remarkable heterogeneity with regard to morphology, molecular signature, and physiology. A key question in glial biology is how such heterogeneity arises during brain development. One approac
Publikováno v:
Curr Biol
Summary Endogenous rhythmic behaviors are evolutionarily conserved and essential for life. In mammalian and invertebrate models, well-characterized neuronal circuits and evolutionarily conserved mechanisms regulate circadian behavior and sleep [ 1 ,
Publikováno v:
JOURNAL OF BIOLOGICAL RHYTHMS
Artículos CONICYT
CONICYT Chile
instacron:CONICYT
Artículos CONICYT
CONICYT Chile
instacron:CONICYT
RNA-binding proteins mediate posttranscriptional functions in the circadian systems of multiple species. A conserved RNA recognition motif (RRM) protein encoded by the lark gene is postulated to serve circadian output and molecular oscillator functio