Regulation of the selective uptake of high density lipoprotein-associated cholesteryl esters by human fibroblasts and Hep G2 hepatoma cells.

Autor: F Rinninger, R C Pittman

Publikováno v: Journal of Lipid Research, Vol 29, Iss 9, Pp 1179-1194 (1988)

We have previously shown that the liver and steroidogenic tissues of rats in vivo and a wider range of cells in vitro, including human cells, selectively take up high density lipoprotein (HDL) cholesteryl esters without parallel uptake of HDL particl

Externí odkaz: https://doaj.org/article/8dfaa8ed92874ac88b116452ac393dac

FoxO transcription factors are required for hepatic HDL cholesterol clearance

Autor: Ido Haimi, Rajasekhar Ramakrishnan, F. Rinninger, Jing Liu, Gabriella Belnavis, Joerg Heeren, Markus Heine, Alexander W. Fischer, Rebecca A. Haeusler, Henry N. Ginsberg, Samuel X. Lee, Christian Schlein

Insulin resistance and type 2 diabetes are associated with low levels of high-density lipoprotein cholesterol (HDL-C). The insulin-repressible FoxO transcription factors are potential mediators of the effect of insulin on HDL-C. FoxOs mediate a subst

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c7677d728e25ccac8d61ef640415a9d
https://europepmc.org/articles/PMC5873864/

Thermogenic adipocytes promote HDL turnover and reverse cholesterol transport

Autor: Jimmy F.P. Berbée, M. Lisa Cherradi, Alexander Bartelt, Klaus Toedter, Mariëtte R. Boon, Joerg Heeren, Markus Heine, Sander L. J. Wijers, Clara John, Nicola Schaltenberg, Christian Schlein, F. Rinninger, Wouter D. van Marken Lichtenbelt, Markus Fischer, Anna Worthmann, Julia Piepenburg, Ludger Scheja, Patrick C.N. Rensen, Stefan K. Nilsson, Andreas Niemeier

Publikováno v: Nature Communications
Nature Communications, 8
Nature Communications, 8:15010. Nature Publishing Group
Nature Communications, Vol 8, Iss 1, Pp 1-10 (2017)

Brown and beige adipocytes combust nutrients for thermogenesis and through their metabolic activity decrease pro-atherogenic remnant lipoproteins in hyperlipidemic mice. However, whether the activation of thermogenic adipocytes affects the metabolism

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b7dafcc60f37653488c961c3f64e61f
https://doi.org/10.1038/ncomms15010

Scavenger receptor CD36 mediates uptake of high density lipoproteins in mice and by cultured cells

Autor: Martin Merkel, Thomas Dobner, Kathryn J. Moore, May Brundert, F. Rinninger, Rajasekhar Ramakrishnan, Antonella Carambia, Peter Groitl, Johannes Herkel, Joerg Heeren

Publikováno v: Journal of Lipid Research, Vol 52, Iss 4, Pp 745-758 (2011)

The mechanisms of HDL-mediated cholesterol transport from peripheral tissues to the liver are incompletely defined. Here the function of scavenger receptor cluster of differentiation 36 (CD36) for HDL uptake by the liver was investigated. CD36 knocko

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46aa5feff32de2dd5e01a0c3fcdf632a
https://doi.org/10.1194/jlr.m011981

SR-BI inhibits ABCG1-stimulated net cholesterol efflux from cells to plasma HDL

Autor: Alan R. Tall, May Brundert, Nan Wang, Takafumi Senokuchi, Tamara A. Pagler, Laurent Yvan-Charvet, Hongna Li, F. Rinninger

Publikováno v: Journal of Lipid Research, Vol 49, Iss 1, Pp 107-114 (2008)

This study compares the roles of ABCG1 and scavenger receptor class B type I (SR-BI) singly or together in promoting net cellular cholesterol efflux to plasma HDL containing active LCAT. In transfected cells, SR-BI promoted free cholesterol efflux to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b465fd308de9a005fb30e115d5eeab6
https://doi.org/10.1194/jlr.m700200-jlr200