Zobrazeno 1 - 9 of 9 pro vyhledávání: '"F R Pieper"'
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Autor: J van der Kaa, G J Platenburg, J D Leung, F R Pieper, D O Co, S Hengst, Anita Borowski, F R Jirik, Carl Perez, J I Drayer
Publikováno v: Chromosome Research. 8:183-191
We have generated transgenic mice by pronuclear microinjection of a murine satellite DNA-based artificial chromosome (SATAC). As 50% of the founder progeny were SATAC-positive, this demonstrates that SATAC transmission through the germline had occurr
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c58a298ee7a46ebf48e5498066a25c97
https://doi.org/10.1023/a:1009206926548
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2
Expression analysis of the individual bovine β-,αs2- and κ-casein genes in transgenic mice
Autor: P M Kooiman, F R Pieper, Monique Rijnkels, Paul J.A. Krimpenfort, H. A. De Boer
Publikováno v: Biochemical Journal. 311:929-937
To identify cis-acting regulatory elements involved in the regulation of expression of the casein genes, the bovine beta-, alpha s2- and kappa-casein genes were isolated from cosmid libraries and introduced into the murine germline. Bovine casein exp
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6e676ff17f31bfa5e956a31676cf2167
https://doi.org/10.1042/bj3110929
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3
Generation of transgenic mice and germline transmission of a mammalian artificial chromosome introduced into embryos by pronuclear microinjection
Autor: D O, Co, A H, Borowski, J D, Leung, J, van der Kaa, S, Hengst, G J, Platenburg, F R, Pieper, C F, Perez, F R, Jirik, J I, Drayer
Publikováno v: Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology. 8(3)
We have generated transgenic mice by pronuclear microinjection of a murine satellite DNA-based artificial chromosome (SATAC). As 50% of the founder progeny were SATAC-positive, this demonstrates that SATAC transmission through the germline had occurr
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::9f7da0a21a69edb754e2dcda16203e2a
https://pubmed.ncbi.nlm.nih.gov/10841045
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4
High-level expression of bovine alpha s1-casein in milk of transgenic mice
Autor: M, Rijnkels, P M, Kooiman, G J, Platenburg, M, van Dixhoorn, J H, Nuijens, H A, de Boer, F R, Pieper
Publikováno v: Transgenic research. 7(1)
The bovine alpha s1-casein gene, isolated from a cosmid library, was introduced into the murine germline. Transgene expression occurred in all transgenic mice, and was confined to the lactating mammary gland. Half of the mouse lines (five out of ten)
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::09553275f0c51ab6d3e44ea8cfb10e2a
https://pubmed.ncbi.nlm.nih.gov/9556911
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5
Muscle-specific expression of a dominant negative desmin mutant in transgenic mice
Autor: J M, Raats, G, Schaart, J B, Henderik, A, van der Kemp, I, Dunia, E L, Benedetti, F R, Pieper, F C, Ramaekers, H, Bloemendal
Publikováno v: European journal of cell biology. 71(3)
To extend our knowledge of the functions of desmin and vimentin intermediate filaments in the developing organism, a construct encoding a truncated desmin subunit driven by the desmin promoter (pDDV), was introduced into the murine germ line. The res
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::cd21ff33909ee8ef4611ebbdcbd67e67
https://pubmed.ncbi.nlm.nih.gov/8929561
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6
Disruption of vimentin intermediate filaments in transgenic mice by expression of a dominant negative mutant desmin subunit
Autor: F R, Pieper, J M, Raats, G, Schaart, I, Dunia, A, van der Kemp, E L, Benedetti, F C, Ramaekers, H, Bloemendal
Publikováno v: European journal of cell biology. 68(4)
To investigate putative functions of vimentin intermediate filaments in the context of intact tissues and the developing organism, a construct (pVDV), driven by the vimentin promoter and encoding a truncated desmin subunit, was introduced into the mu
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::68d8c1ec201c65f4856536fab33cda18
https://pubmed.ncbi.nlm.nih.gov/8690015
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7
Expression analysis of the individual bovine beta-, alpha s2- and kappa-casein genes in transgenic mice
Autor: M, Rijnkels, P M, Kooiman, P J, Krimpenfort, H A, de Boer, F R, Pieper
Publikováno v: The Biochemical journal. 311
To identify cis-acting regulatory elements involved in the regulation of expression of the casein genes, the bovine beta-, alpha s2- and kappa-casein genes were isolated from cosmid libraries and introduced into the murine germline. Bovine casein exp
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::313d835d2ce0f864a55b93244cf87152
https://pubmed.ncbi.nlm.nih.gov/7487953
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8
Tissue-specific expression of a vimentin-desmin hybrid gene in transgenic mice
Autor: Hans Bloemendal, G. J. van Eys, R. M. van den Heuvel, Paul Krimpenfort, W. T. Vree Egberts, F. C. Ramaekers, Anton Berns, H. T. Cuypers, F. R. Pieper, G. Schaart
Publikováno v: The EMBO Journal. 7:941-947
We have introduced a hybrid gene, pVVim2, composed of the 5' region of the hamster vimentin gene encoding the head and rod domain of vimentin and the 3' region of the hamster desmin gene encoding the tail domain of desmin, into the germ line of mice
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fff39b7bbe1e6c8d593ce1e94116b65
https://doi.org/10.1002/j.1460-2075.1988.tb02899.x
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