Zobrazeno 1 - 10
of 17
pro vyhledávání: '"F P, Zemlan"'
Autor:
F. P. Zemlan
Publikováno v:
Journal of Neural Transmission. 103:1105-1116
The present study examines the safety and efficacy of the centrally acting cholinesterase inhibitor, velnacrine, in treating the cognitive symptoms of Alzheimer's disease. Seven hundred thirty-five patients with mild-to-severe Alzheimer's disease wer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7b126ac986e2e9a0a57642098934c660
https://doi.org/10.1007/bf01291795
https://doi.org/10.1007/bf01291795
Autor:
R. C. Green, F. P. Zemlan, W. E. Reichman, Piero Antuono, S. R. Cohen, J. E. Shipley, F. J. Huff, M. Alter, J. E. Delagandara, N. R. Cutler, M. A. McDonald, M. L. Crismon
Publikováno v:
Alzheimer Disease & Associated Disorders. 10:93-102
Besipirdine hydrochloride (HP 749) is an indole-substituted analog of 4-aminopyridine. Besipirdine enhances both cholinergic and adrenergic neurotransmission in the central nervous system. The present study examined the efficacy and tolerability of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::262a66ac7bda7112dc076388f04531c2
https://doi.org/10.1097/00002093-199601020-00007
https://doi.org/10.1097/00002093-199601020-00007
Autor:
F P, Zemlan, G E, Dean
Publikováno v:
Journal of neuroscience research. 46(1)
Paired helical filaments (PHFs) purified from alzheimer's brain consist of hyperphosphorylated microtubule-associated protein tau. In PHF, phosphorylation occurs at ser/thr tau residues. Several of these ser/thr phosphorylation sites lie immediately
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6e3c875a779e18a2e0ef4b6338f1745f
https://pubmed.ncbi.nlm.nih.gov/8892109
https://pubmed.ncbi.nlm.nih.gov/8892109
Autor:
F P, Zemlan
Publikováno v:
Journal of neural transmission (Vienna, Austria : 1996). 103(8-9)
The present study examines the safety and efficacy of the centrally acting cholinesterase inhibitor, velnacrine, in treating the cognitive symptoms of Alzheimer's disease. Seven hundred thirty-five patients with mild-to-severe Alzheimer's disease wer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b27cfca9de7393c7f1399c2da6be7e3f
https://pubmed.ncbi.nlm.nih.gov/9013398
https://pubmed.ncbi.nlm.nih.gov/9013398
Publikováno v:
Pharmacology. 48(1)
The present study examined whether the effect of stimulation of the nucleus raphe magnus (NRM) is mediated by spinal cord dorsal horn serotonin1A (5-HT1A) receptors in the rat. This hypothesis predicts that nociceptive dorsal horn units inhibited by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::eb2705ef6ca5257ff962576ee82fdc6e
https://pubmed.ncbi.nlm.nih.gov/8309982
https://pubmed.ncbi.nlm.nih.gov/8309982
Autor:
F P Zemlan, R M Murphy
Publikováno v:
Neuroreport. 3(10)
The spinal cord distribution of a recently identified, high affinity 3H-5-HT binding site, the 5-HT1S receptor was studied employing quantitative autoradiography with microdensitometry. The laminar distribution and density of other high affinity 3H-5
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe81b5809f2948c6dadd0c23e82b48ea
https://pubmed.ncbi.nlm.nih.gov/1421084
https://pubmed.ncbi.nlm.nih.gov/1421084
Autor:
F P, Zemlan, E F, Schwab
Publikováno v:
Journal of neurochemistry. 57(6)
Three pharmacologically distinct high-affinity [3H]serotonin ([3H]5-HT) binding sites were identified in spinal cord synaptosomes. [3H]5-HT competition studies using selective 5-HT1A receptor ligands indicated that approximately 25% of high-affinity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::18c0001fedd3de68bc7593e9f5eb73ef
https://pubmed.ncbi.nlm.nih.gov/1834802
https://pubmed.ncbi.nlm.nih.gov/1834802
Publikováno v:
Psychiatrie, Neurologie, und medizinische Psychologie. 42(5)
This study evaluated the putative impact of circulating anticholinergic equivalents on cognitive functional performance in non-demented geropsychiatric inpatients. Standard rating instruments were administered to measure memory functions, concentrati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1764cb2c582cf09fa7297cdddfef7fcd
https://pubmed.ncbi.nlm.nih.gov/1975100
https://pubmed.ncbi.nlm.nih.gov/1975100
Publikováno v:
Progress in neuro-psychopharmacologybiological psychiatry. 14(1)
1. Clinical variables determining length of psychiatric hospitalization for psychotic inpatients were explored. Forty psychotic inpatients received a 14 day fixed dose neuroleptic trial. 2. Neuroleptic responders (25/40) were discharged 15 +/- 2 days
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0055a28951c875f1ea47cc9f3779bf4e
https://pubmed.ncbi.nlm.nih.gov/2300678
https://pubmed.ncbi.nlm.nih.gov/2300678
Publikováno v:
The Journal of Immunology. 141:3937-3944
The study of polymorphonuclear neutrophil (PMN) surface receptor expression provides a means for the assessment of PMN function and state of cellular activation. In this study, we characterized binding of the chemotactic peptide FMLP to whole PMN, wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6ccf6ec5a9cf6a917675564107eb606e
https://doi.org/10.4049/jimmunol.141.11.3937
https://doi.org/10.4049/jimmunol.141.11.3937