Zobrazeno 1 - 10
of 20
pro vyhledávání: '"F P, Lafeber"'
Autor:
Wietse Kuis, Huib de Jong, Berent J. Prakken, Margje H. Haverkamp, Johannes W. J. Bijlsma, Wilco de Jager, Salvatore Albani, Floris F. P. Lafeber
Publikováno v:
Arthritis and Rheumatism, 60, 1966-76
Arthritis and Rheumatism, 60, 7, pp. 1966-76
Arthritis and Rheumatism, 60, 7, pp. 1966-76
Item does not contain fulltext OBJECTIVE: Human Hsp60 is expressed in the joints of patients with rheumatoid arthritis (RA) and can elicit a regulatory T cell response in the peripheral blood and synovial fluid. However, Hsp60 can also trigger strong
Autor:
J, DeGroot, N, Verzijl, M J, Wenting-Van Wijk, R A, Bank, F P, Lafeber, J W, Bijlsma, J M, TeKoppele
Publikováno v:
Arthritis and rheumatism. 44(11)
Progressive destruction of articular cartilage is a hallmark of osteoarthritis (OA) and rheumatoid arthritis (RA). Age-related changes in cartilage may influence tissue destruction and thus progression of the disease. Therefore, the effect of age-rel
Publikováno v:
The Journal of rheumatology. 28(9)
Both interleukin 4 (IL-4) and IL-10, separately and in combination, and under in vitro and in vivo conditions in animals, have been reported to inhibit characteristics of rheumatoid arthritis (RA) and experimentally induced arthritis. We investigated
Autor:
J C, Dekkers, R, Geenen, G L, Godaert, K A, Glaudemans, F P, Lafeber, L J, van Doornen, J W, Bijlsma
Publikováno v:
The Journal of rheumatology. 28(7)
There is evidence that the hypothalamic pituitary adrenal (HPA) axis is subresponsive in patients with rheumatoid arthritis (RA). We assessed HPA axis responses to experimental stressors mimicking daily life challenges in patients with RA to determin
Publikováno v:
Arthritis and rheumatism. 44(1)
Autor:
N, Verzijl, J, DeGroot, E, Oldehinkel, R A, Bank, S R, Thorpe, J W, Baynes, M T, Bayliss, J W, Bijlsma, F P, Lafeber, J M, Tekoppele
Publikováno v:
The Biochemical journal.
Non-enzymic modification of tissue proteins by reducing sugars, the so-called Maillard reaction, is a prominent feature of aging. In articular cartilage, relatively high levels of the advanced glycation end product (AGE) pentosidine accumulate with a
Publikováno v:
The Journal of rheumatology. 27(7)
It has been shown that cartilage is damaged upon intraarticular hemorrhage. We investigated differences in the susceptibility of cartilage from young adult and old animals to blood induced joint damage in a canine in vivo model.Right knees of 6 young
Publikováno v:
Clinical and experimental rheumatology. 17(3)
The clinical effects of high dosage pulse glucocorticosteroid (GS) infusion as a treatment for rheumatoid arthritis (RA) differ considerably between patients. The aim of the present study was to gain more insight into these differences in clinical re
Publikováno v:
Arthritis and rheumatism. 42(5)
To investigate the direct and indirect (via synovial inflammation) effects of intraarticular bleeding on cartilage in vivo.Right knees of 14 beagle dogs were injected with autologous blood on days 0 and 2. Cartilage matrix proteoglycan turnover, coll
Publikováno v:
Arthritis and rheumatism. 42(5)
To investigate mechanisms underlying cartilage damage caused by brief exposure of cartilage to blood, such as that occurring during intraarticular bleeding.Human articular cartilage was cultured for 4 days in the presence of blood (components; 7.5-50