Zobrazeno 1 - 10
of 39
pro vyhledávání: '"F N, Ziyadeh"'
Publikováno v:
Clinical and experimental nephrology. 6(3)
The manifestation of diabetic nephropathy may be a consequence of the actions of certain cytokines and growth factors. Prominent among them is transforming growth factor-β (TGF-β), which promotes renal cell hypertrophy and stimulates extracellular
Publikováno v:
Proceedings of the Association of American Physicians. 111:357-364
Angiotensin II (ANG II) induces cellular hypertrophy of cultured proximal tubular cells from various species. This hypertrophic response is associated with an increase in synthesis of basement membrane-associated collagen type IV. Previous investigat
Autor:
András Mogyorósi, F N Ziyadeh
Publikováno v:
Nephrology Dialysis Transplantation. 14:1078-1081
The small proteoglycan decorin may intercept the activity of the TGF-beta system. Decorin administration has been advocated as potential therapy in renal fibrotic diseases, because of the findings of a relative deficiency of decorin and a relative ex
Autor:
K. Sharma, F. N. Ziyadeh, B. Alzahabi, T. A. McGowan, S. Kapoor, B. R. Kurnik, P. B. Kurnik, L. S. Weisberg
Publikováno v:
Diabetes. 46:854-859
Publikováno v:
Journal of biological regulators and homeostatic agents. 27(3)
Diabetic nephropathy (DN) is one of the most serious complications of type I and type II diabetes. DN is characterized by hyperfiltration, hypertrophy, extracellular matrix accumulation, and proteinuria. This advances into renal fibrosis and loss of
Autor:
K. Sharma, F. N. Ziyadeh
Publikováno v:
Diabetes. 44:1139-1146
Publikováno v:
Diabetes. 40:465-471
Publikováno v:
Contributions to nephrology. (135)
Autor:
S, Goldfarb, F N, Ziyadeh
Publikováno v:
Transactions of the American Clinical and Climatological Association. 112
In summary, metabolic, hemodynamic, and genetic factors are all important in the development and progression of diabetic nephropathy (33). Recent studies using cell culture techniques and experimental animal models have provided important insight int
Publikováno v:
Kidney international. 56(3)
Leptin inhibits food intake and increases energy expenditure. Although the kidney expresses abundant transcripts of the short form of the leptin receptor (Ob-Ra), a role for this hormone in renal function remains unclear. Because individuals with mas