Zobrazeno 1 - 10
of 24
pro vyhledávání: '"F N, Dzhakhangirov"'
Publikováno v:
Chemistry of Natural Compounds. 52:849-852
The in vivo antidote activity of 72 diterpenoid alkaloids isolated from plants of the genera Aconitum, Delphinium, and Consolida and their derivatives was tested against poisoning of mice by a lethal dose of aconitine. The structure–activity relati
Spasmolytic activity of diterpenoid alkaloids and their derivatives. Structure–activity relationship
Publikováno v:
Chemistry of Natural Compounds. 49:702-706
The spasmolytic activity of diterpenoid alkaloids of various structural types that were isolated from plants of the genera Aconitum, Delphinium, and Consolida and their synthetic derivatives was studied in vitro using the barium-chloride contraction
Publikováno v:
Chemistry of Natural Compounds. 45:685-689
An excess of periodic acid was reacted with the diterpenoid alkaloid demethyleneldelidine (1) to produce a γ-lactone (2) in which the carbonyl at the C6-position was selectively reduced by an excess of NaBH4. The conformation of the rings, configura
Autor:
S. K. Usmanova, R. Sh. Shakirov, K. R. Kasymova, B. T. Salimov, M. N. Sultankhodzhaev, F. N. Dzhakhangirov
Publikováno v:
Chemistry of Natural Compounds. 43:581-589
The toxicity and local anesthetic activity of 74 diterpenoid alkaloids differing in the nature and position of functional groups in lycoctonine, heteratisine, napelline, hetisane, atisane, and denudatine skeletons and their synthetic derivatives were
Publikováno v:
Chemistry of Natural Compounds. 40:151-155
The structure of the new diterpenoid alkaloid 12-acetyl-12-epinapelline that was isolated from the mother liquor of Aconitum soongoricum was established. The conformational state of ring A was analyzed. Spectral properties and data for the antiarhyth
Autor:
F. N. Dzhakhangirov, I. A. Bessonova
Publikováno v:
Chemistry of Natural Compounds. 38:74-77
The biological activity of 11 alkaloids isolated from Aconitum coreanum was studied. The compounds exhibit myorelaxant activity. Isoatisine and coryphine, which contain oxazolidine rings, are the most active. N-Oxides of 2-isobutyryl-14-hydroxyhetisi
Autor:
Bakhtiyor Rasulev, M. A. Turabekova, Danuta Leszczynska, F. N. Dzhakhangirov, Jerzy Leszczynski, Andrey A. Toropov
Publikováno v:
Journal of environmental science and health. Part C, Environmental carcinogenesisecotoxicology reviews. 32(3)
The duration of anesthesia (related to protein binding of a drug) and the onset time (determined by the pKa) are important characteristics in assessment of local anesthetic agents. They are known to be affected by a number of factors. Early studies o
Publikováno v:
Chemistry of Natural Compounds. 34:480-483
Publikováno v:
Chemistry of Natural Compounds. 33:190-202
The cardiotropic activities of 111 diterpene alkaloids and their synthetic derivatives having lycoctine, heteratisine, napelline, and denudatine skeletons have been studied. It has been established that the overwhelming majority of these compounds ex
Publikováno v:
Chemistry of Natural Compounds. 31:708-713
A number of diterpene alkaloids (DAs) and their derivatives have been investigated for curaremimetic activity. Their structure-activity relationships and the mechanisms of their action have been studied. Structural fragments of the DAs that are respo