Zobrazeno 1 - 10
of 279
pro vyhledávání: '"F Moffat"'
This edited volume provides insights about the molecular virology, pathoenesis of infection and host responses to varicella-zoster virus, which is a medically important human herpesvirus. The chapters not only discuss genetics and molecular evolution
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-15 (2022)
Abstract H84T BanLec is a molecularly engineered lectin cloned from bananas with broad-spectrum antiviral activity against several RNA viruses. H84T BanLec dimers bind glycoproteins containing high-mannose N-glycans on the virion envelope, blocking a
Externí odkaz:
https://doaj.org/article/9ae4f1b582a845d989fb3e376287a90f
Autor:
Allen T. Esterly, Megan G. Lloyd, Prashant Upadhyaya, Jennifer F. Moffat, Saravanan Thangamani
Publikováno v:
JID Innovations, Vol 2, Iss 4, Pp 100128- (2022)
Arboviruses such as flaviviruses and alphaviruses cause a significant human healthcare burden on a global scale. Transmission of these viruses occurs during human blood feeding at the mosquito-skin interface. Not only do pathogen immune evasion strat
Externí odkaz:
https://doaj.org/article/7bd5edacb2ca4a719bb77341165c777d
Autor:
Uma S. Singh, Ananda K. Konreddy, Yugandhar Kothapalli, Dongmei Liu, Megan G. Lloyd, Vidya Annavarapu, Catherine A. White, Michael. G. Bartlett, Jennifer F. Moffat, Chung K. Chu
Publikováno v:
Journal of Medicinal Chemistry. 66:7038-7053
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e84519d992e3eeca6b892094069644f7
https://doi.org/10.1021/acs.jmedchem.3c00545
https://doi.org/10.1021/acs.jmedchem.3c00545
Autor:
Megan G. Lloyd, Michael B. Yee, Joseph S. Flot, Dongmei Liu, Brittany W. Geiler, Paul R. Kinchington, Jennifer F. Moffat
Publikováno v:
Viruses, Vol 14, Iss 4, p 826 (2022)
There is a continued need to understand varicella-zoster virus (VZV) pathogenesis and to develop more effective antivirals, as it causes chickenpox and zoster. As a human-restricted alphaherpesvirus, the use of human skin in culture and mice is criti
Externí odkaz:
https://doaj.org/article/396dff2fd53c4aea84767c2f6dc1fa9a
Autor:
K A Bain, B Nichols, F Moffat, C Kerbiriou, U Z Ijaz, K Gerasimidis, I B McInnes, A Åstrand, S Holmes, S W F Milling
Publikováno v:
Clinical and Experimental Immunology. 210:175-186
Alopecia areata (AA) is an immune-mediated disease that causes non-scarring hair loss. Autoreactive CD8 T cells are key pathogenic effectors in the skin, and AA has been associated both with atopy and with perturbations in intestinal homeostasis. Thi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd24247e5f15c9fb79696641a8a54808
https://doi.org/10.1093/cei/uxac088
https://doi.org/10.1093/cei/uxac088
Publikováno v:
Nutrients, Vol 13, Iss 11, p 3681 (2021)
Children eat more fruits and vegetables when more are available at home, but less is known about how the neighborhood food environment relates to children’s diet and weight outcomes. The goal of this study was to determine whether parental percepti
Externí odkaz:
https://doaj.org/article/654ca11b0621471787718464bcff62ce
Autor:
Diana S. Moura, Carlos J. Pestana, Colin F. Moffat, Jianing Hui, John T.S. Irvine, Linda A. Lawton
The authors would like to thank the Hydro Nation Scholar Programme funded by the Scottish Government through the Scottish Funding Council and managed by the Hydro Nation International Centre for funding this research. The authors would like to thank
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6d8be075f1d9dc7ee015711919776a2
https://hdl.handle.net/10023/27501
https://hdl.handle.net/10023/27501
Autor:
Stephen B. Fox, Amanda Grattan, Alena Reznichenko, Celine Faure, Vanathi Sivasubramaniam, David F. Moffat, Annabelle Mahar, Connull Leslie, Christine Khoo, Peter J. Jessup, David Godbolt, Edwina E. Duhig, Maya Cherian, Prudence A. Russell, Wendy A. Cooper
Table S2 shows agreement with gold standard depending on PD-L1 tumor proportion score per gold standard. Agreements for trained and untrained participating pathologists were compared.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cb7339dbfe8c397d5a95c1f0f949dce
https://doi.org/10.1158/1078-0432.22463645.v1
https://doi.org/10.1158/1078-0432.22463645.v1
Autor:
Stephen B. Fox, Amanda Grattan, Alena Reznichenko, Celine Faure, Vanathi Sivasubramaniam, David F. Moffat, Annabelle Mahar, Connull Leslie, Christine Khoo, Peter J. Jessup, David Godbolt, Edwina E. Duhig, Maya Cherian, Prudence A. Russell, Wendy A. Cooper
Purpose: Reliable and reproducible methods for identifying PD-L1 expression on tumor cells are necessary to identify responders to anti–PD-1 therapy. We tested the reproducibility of the assessment of PD-L1 expression in non–small cell lung cance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01796b796f92416cf71266f25632938c
https://doi.org/10.1158/1078-0432.c.6525473
https://doi.org/10.1158/1078-0432.c.6525473