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pro vyhledávání: '"F M Brunelle"'
Publikováno v:
Biopharmaceutics & Drug Disposition. 17:311-317
In vitro glucuronidation was studied in liver microsomes from two patients with Crigler-Najjar type I (CN-I) disease and compared with the activity measured in microsomes prepared from six control human livers. The UDP-glucuronosyltransferase (UGT) a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::90f323ea0e5f3655ed0cb412a266649a
https://doi.org/10.1002/(sici)1099-081x(199605)17:4<311::aid-bdd953>3.0.co
https://doi.org/10.1002/(sici)1099-081x(199605)17:4<311::aid-bdd953>3.0.co
Autor:
F M Brunelle, Roger K. Verbeeck
Publikováno v:
Xenobiotica. 26:123-131
1. The glucuronidation of diflunisal to its phenolic (DPG) and acyl glucuronide (DAG) was measured in vitro using microsomes prepared from rat (n = 4) and human (n = 6) liver and kidney tissue. UGT activities towards bilirubin, 4-nitrophenol and (-)-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f90c6669d8e6f91ae0de3379d9c30cb
https://doi.org/10.3109/00498259609046694
https://doi.org/10.3109/00498259609046694
Publikováno v:
Biopharmaceuticsdrug disposition. 17(4)
In vitro glucuronidation was studied in liver microsomes from two patients with Crigler-Najjar type I (CN-I) disease and compared with the activity measured in microsomes prepared from six control human livers. The UDP-glucuronosyltransferase (UGT) a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a5c56802829564e8dd66f3c3f5c6a267
https://pubmed.ncbi.nlm.nih.gov/8743402
https://pubmed.ncbi.nlm.nih.gov/8743402
Autor:
F M, Brunelle, R K, Verbeeck
Publikováno v:
Biochemical pharmacology. 46(11)
The in vitro formation rates of the phenolic (DPG) and acyl (DAG) glucuronides of diflunisal were investigated using rat liver microsomes. Preliminary studies showed that DAG hydrolysed rapidly (T1/2 = 12 min) when incubated in the presence of rat li
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8f07f3fa9ac76348bb5084e0229f8231
https://pubmed.ncbi.nlm.nih.gov/8267644
https://pubmed.ncbi.nlm.nih.gov/8267644