Výsledky vyhledávání - "F M, Raaphorst"

High expression of Polycomb group protein EZH2 predicts poor survival in salivary gland adenoid cystic carcinoma

Autor: Charles R. Leemans, F M Raaphorst, M van Lohuizen, I. van der Waal, Elisabeth Bloemena, Arie P. Otte, Hedy Vékony

Publikováno v: Journal of clinical pathology, 61(6), 744-749. BMJ Publishing Group
Journal of Clinical Pathology, 61(6), 744-749. BMJ Publishing Group
Vekony, H, Raaphorst, F M, Otte, AP, van Lohuizen, M, Leemans, C R, van der Waal, I & Bloemena, E 2008, ' High expression of Polycomb group protein EZH2 predicts poor survival in salivary gland adenoid cystic carcinoma ', Journal of Clinical Pathology, vol. 61, no. 6, pp. 744-749 . https://doi.org/10.1136/jcp.2007.054262
Vékony, H, Raaphorst, F M, Otte, A P, van Lohuizen, M, Leemans, C R, van der Waal, I & Bloemena, E 2008, ' High expression of Polycomb group protein EZH2 predicts poor survival in salivary gland adenoid cystic carcinoma ', Journal of Clinical Pathology, vol. 61, no. 6, pp. 744-749 . https://doi.org/10.1136/jcp.2007.054262

Background: The prognosis of adenoid cystic carcinoma (ACC), a malignant salivary gland tumour, depends on clinicopathological parameters. To decipher the biological behaviour of ACC, and to identify patients at risk of developing metastases, additio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a8b5ea92519a7a3d0ea552144a81eba
https://research.vu.nl/en/publications/4bb5c7b3-10eb-49af-a173-75f07c730d63

Zobrazit plný text záznamu

Deregulated expression of p16INK4a and p53 pathway members in benign and malignant myoepithelial tumours of the salivary glands

Autor: Charles R. Leemans, I. van der Waal, Hedy Vékony, F M Raaphorst, Elisabeth Bloemena, Kerstin Röser, Thomas Löning

Publikováno v: Histopathology, 53(6), 658-666. Wiley-Blackwell
Vekony, H, Roser, K, Loning, T, Raaphorst, F M, Leemans, C R, van der Waal, I & Bloemena, E 2008, ' Deregulated expression of p16INK4a and p53 pathway members in benign and malignant myoepithelial tumours of the salivary glands ', Histopathology, vol. 53, no. 6, pp. 658-666 . https://doi.org/10.1111/j.1365-2559.2008.03184.x
Vékony, H, Röser, K, Löning, T, Raaphorst, F M, Leemans, C R, van der Waal, I & Bloemena, E 2008, ' Deregulated expression of p16INK4a and p53 pathway members in benign and malignant myoepithelial tumours of the salivary glands ', Histopathology, vol. 53, no. 6, pp. 658-666 . https://doi.org/10.1111/j.1365-2559.2008.03184.x

Aims: Myoepithelial salivary gland tumours are uncommon and follow an unpredictable biological course. The aim was to examine their molecular background to acquire a better understanding of their clinical behaviour.Methods and results: Expression of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::220e8ffc0324e724636babf3f08a79cc
https://hdl.handle.net/11245/1.298134

Zobrazit plný text záznamu

Expression pattern of the most JH-proximal human VH gene segment (VH6) in the B cell and antibody repertoire suggests a role of VH6-encoded IgM antibodies in early ontogeny

Autor: J H Van Es, F M Raaphorst, M J van Tol, F H Meyling, T Logtenberg

Publikováno v: The Journal of Immunology. 150:161-168

We have developed a mAb (JE-6) that recognizes an Id encoded by the most JH-proximal human VH gene segment (VH6) in or near germ-line configuration. This mAb was used to determine the frequency of Id JE6+ B cells in large collections of monoclonal EB

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::43b11547f850503206f4eac391e3d243
https://doi.org/10.4049/jimmunol.150.1.161

Zobrazit plný text záznamu

The Polycomb group protein EZH2 is upregulated in proliferating, cultured human mantle cell lymphoma

Autor: H P, Visser, M J, Gunster, H C, Kluin-Nelemans, E M, Manders, F M, Raaphorst, C J, Meijer, R, Willemze, A P, Otte

Publikováno v: British journal of haematology. 112(4)

Polycomb group (PcG) proteins are involved in the stable transmittance of the repressive state of their gene targets throughout the cell cycle. Mis-expression of PcG proteins can lead to proliferative defects and tumorigenesis. There are two separate

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::aa9e74afffe8813b932d4b437dc87dc0
https://pubmed.ncbi.nlm.nih.gov/11298590

Zobrazit plný text záznamu

Bone marrow transplantation, fetal B-cell repertoire development, and the mechanism of immune reconstitution

Autor: F M, Raaphorst

Publikováno v: Blood. 92(12)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::d0b6f2c1b895a6957ab3b5a5103358e5
https://pubmed.ncbi.nlm.nih.gov/9988545

Zobrazit plný text záznamu

The role of Homeobox genes in normal hematopiesis and hematological malignancies

Autor: J. W. Van Oostveen, J. J. M. Walboomers, F. M. Raaphorst, J. J. Bijl, C. J. L. M. Meijer

Publikováno v: Leukemia, 13, 1675-1690. Nature Publishing Group
van Oostveen, J W, Bijl, J J, Raaphorst, F M, Walboomers, J M M & Meijer, C J L M 1999, ' The role of Homeobox genes in normal hematopiesis and hematological malignancies ', Leukemia, vol. 13, pp. 1675-1690 . https://doi.org/10.1038/sj.leu.2401562

In the last decade it has become clear that homeobox containing genes (HOX genes) not only play a significant role in regulating body formation, but in addition, they are contributing to organization and regulation of hematopoiesis. Modern molecular

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69a2f30364834848e6500fa1d0ce5cbd
https://research.vumc.nl/en/publications/6565f0b4-88d6-41f8-94e6-3c5440a1ace9

Zobrazit plný text záznamu

Ig heavy chain third complementarity determining regions (H CDR3s) after stem cell transplantation do not resemble the developing human fetal H CDR3s in size distribution and Ig gene utilization

Autor: E, Gokmen, F M, Raaphorst, D H, Boldt, J M, Teale

Publikováno v: Blood. 92(8)

Previous studies have suggested that the B-cell repertoire after stem cell transplantation resembles the developing repertoire in the fetus. Fetal and adult repertoires differ strikingly at the molecular level in Ig heavy chain third complementarity

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::60410d53895b1c741fd7a4611c62acaa
https://pubmed.ncbi.nlm.nih.gov/9763565

Zobrazit plný text záznamu

Expression of the human immunoglobulin heavy chain VH6 gene element by fetal B lymphocytes

Autor: F. M. Raaphorst, J. L. M. Waaijer, R. Langlois Van Den Bergh, J. M. J. J. Vossen, M.J.D. van Tol

Publikováno v: Scandinavian journal of immunology. 46(3)

Fetal B lymphocytes in mice and humans use a limited number of the available VH gene segments. Mouse fetal B cells primarily utilize 3' VH elements, suggesting that the localization of these elements determines their rearrangement frequency. The prev

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b15889bc0bc87fc09abc3f38cc66d186
https://pubmed.ncbi.nlm.nih.gov/9315119

Zobrazit plný text záznamu

Cloning of size-selected human immunoglobulin heavy-chain rearrangements from third complementarity-determining region fingerprint profiles

Autor: F M, Raaphorst, J, Tami, I E, Sanz

Publikováno v: BioTechniques. 20(1)

Methods have been developed to rapidly visualize the size distribution of third complementarity-determining regions (CDR3) in immunoglobulin (Ig) and T-cell receptor (TCR) molecules. DNA fragments spanning the Ig or TCR CDR3 are generated by PCR usin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::d5a53c6d28512c970458e838ae0f5ff3
https://pubmed.ncbi.nlm.nih.gov/8770410

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání