Výsledky vyhledávání - "F M, Pavalko"

Fluid shear-induced mechanical signaling in MC3T3-E1 osteoblasts requires cytoskeleton-integrin interactions

Autor: F M, Pavalko, N X, Chen, C H, Turner, D B, Burr, S, Atkinson, Y F, Hsieh, J, Qiu, R L, Duncan

Publikováno v: The American journal of physiology. 275(6 Pt 1)

Mechanical stimulation of bone induces new bone formation in vivo and increases the metabolic activity and gene expression of osteoblasts in culture. We investigated the role of the actin cytoskeleton and actin-membrane interactions in the transmissi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f132b01d1998acdeba279e9133232cb9
https://pubmed.ncbi.nlm.nih.gov/9843721

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Cytoskeletal interactions with the leukocyte integrin beta2 cytoplasmic tail. Activation-dependent regulation of associations with talin and alpha-actinin

Autor: R, Sampath, P J, Gallagher, F M, Pavalko

Publikováno v: The Journal of biological chemistry. 273(50)

Circulating leukocytes are nonadherent but bind tightly to endothelial cells following activation. The increased avidity of leukocyte integrins for endothelial ligands following activation is regulated, in part, by interaction of the beta2 subunit cy

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::2bf91a547370c9e4766b9564961cf28f
https://pubmed.ncbi.nlm.nih.gov/9837942

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The cytoplasmic domains of E- and P-selectin do not constitutively interact with alpha-actinin and are not essential for leukocyte adhesion

Autor: G S, Kansas, F M, Pavalko

Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 157(1)

The selectins are a family of carbohydrate-binding adhesion molecules involved in the regulation of leukocyte migration. Although there is strong homology between different selectins in their extracellular regions, there is none in the cytoplasmic ta

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::39f637752dbdcd9324ac828ff3254376
https://pubmed.ncbi.nlm.nih.gov/8683133

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Activation of human neutrophils induces an interaction between the integrin beta 2-subunit (CD18) and the actin binding protein alpha-actinin

Autor: F M, Pavalko, S M, LaRoche

Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 151(7)

Mac-1 and LFA-1, members of the leukocyte or CD18 integrin subfamily of adhesion molecules, rapidly change from a low avidity to a high avidity state on activation of neutrophils by various agonists. The control of CD18 integrin-dependent neutrophil

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::2131b92e175e2edc40a32a20bdadc693
https://pubmed.ncbi.nlm.nih.gov/8104223

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The role of phosphorylation and limited proteolytic cleavage of talin and vinculin in the disruption of focal adhesion integrity

Autor: C E, Turner, F M, Pavalko, K, Burridge

Publikováno v: The Journal of biological chemistry. 264(20)

Chemical agents which activate specific kinases were employed to disrupt the stress fiber and focal adhesion organization of cells spread on a substratum. The phorbol ester 12-O-tetradecanoylphorbol-13-acetate, an activator of protein kinase C, promo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::26dc74274711a46806a18baf7f36ca0a
https://pubmed.ncbi.nlm.nih.gov/2545690

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