Zobrazeno 1 - 10
of 37
pro vyhledávání: '"F M, Brennan"'
Autor:
J F M Brennan, A L Denton
Publikováno v:
Journal of the Operational Research Society. 55:413-421
Comprehensive Maritime Patrol Aircraft Systems Simulation (COMPASS) is a mathematical model of the Nimrod MRA4 weapon system that is being developed to enable the prediction of operational effectiveness. COMPASS will be used throughout the Nimrod MRA
Autor:
F M Brennan
Publikováno v:
Rheumatology. 38:293-297
Autor:
J. J. Nietfeld, A. J. Duits, G. Venn, M. E. J. Billingham, Elizabeth C. Arner, T. E. Hardingham, F. M. Brennan, M. Covington
Publikováno v:
Arthritis & Rheumatism. 36:819-826
Objective. To measure levels of cytokines, proteases, and glycosaminoglycans (GAG) in synovial fluid (SF) from the knees of animals with experimental osteoarthritis (OA) and from their contralateral (control) knees, and to compare and correlate these
Publikováno v:
Current topics in microbiology and immunology. 305
The analysis of suppression of cytokines in rheumatoid synovial tissue and fluid pioneered the studies of human cytokines in diseased tissue due to the relative ease of staining samples, even at the height of the inflammatory process. These studies l
Autor:
F. M. Brennan
Publikováno v:
Clinical and Experimental Immunology. 97:1-3
Publikováno v:
Current directions in autoimmunity. 3
Publikováno v:
Advances in experimental medicine and biology. 490
As we enter the 2000's it is clear that cytokine blockade is an effective therapeutic strategy for rheumatoid arthritis. In this brief review, we will review the rationale for anti TNFalpha therapy, the current status of therapy and focus on the regu
Publikováno v:
European journal of immunology. 31(6)
Dendritic cells (DC) are the most potent antigen-presenting cells for naive T cells, due to their high expression of MHC and costimulatory molecules, but relatively little is known about the biochemical pathways that regulate this function. We used t
Publikováno v:
European journal of immunology. 29(7)
The co-ordinate role of the Th1 cytokine IL-12 and the proinflammatory cytokine TNF in arthritis was explored using the DBA/1 mouse model, collagen-induced arthritis (CIA). In this study, mice with established arthritis were treated with anti-IL-12 a