Randomised, open-label, multicentric phase III trial to evaluate the safety and efficacy of palbociclib in combination with endocrine therapy, guided by ESR1 mutation monitoring in oestrogen receptor-positive, HER2-negative metastatic breast cancer patients: study design of PADA-1

Autor: C Cheneau, S Barthier, J Lemonnier, Fabrice Andre, C Dubot, L Teixeira, A Escande, T De La Motte Rouge, T Petit, L Arnould, Laurent Arnould, Suzette Delaloge, Jerome Lemonnier, A Marti, L Stefani, F Berger, C Levy, P Barthelemy, S Nguyen, M Gardner, A Lortholary, François-Clément Bidard, J Plaza, L Joly, Thibault de la Motte Rouge, F Andre, I Bièche, C Alleaume, R Sabatier, B Lucas, Ivan Bieche, O Derbel, L Venat-Bouvet, F Del Piano, Florian Clatot, Anne-Claire Hardy-Bessard, Frédérique Berger, Margaux Marce, Thomas Bachelot, Anne Pradines, Jean-Luc Canon, Sandrine Marques, M Achille, H Ammarguellat, O Arsene, T Bachelot, C Bernard-Marty, F-C Bidard, N Bonichon-Lamichhane, N Bonnin, R Bouaita, A Boudrant, V-A Brunel, C Chakiba, F Clatot, F Dalenc, A De Gramont, L Deiana, C Delbaldo, V Delecroix, H Desclos, V D'Hondt, N Dohollou, J-M Ferrero, C Foa, J-S Frenel, C Garnier Tixidre, D Genet, O Gisserot, M Gozy, C Greilsamer, J Grenier, F Guinet, A-C Hardy-Bessard, J-P Jacquin, E Lachaier, S Ladoire, A-P Laurenty, R Le Scodan, N Leduc, E Legouffe, C Levache, F Lorchel, N Marques, J Medioni, A Melis, D Mille, D Mollon, L Moreau, I Moullet, M-A Mouret-Reynier, A Najem, H Orfeuvre, J-F Paitel, B Pistilli, C Riedl, P Soulie, D Spaeth, F Trouboul, C Valmar, H Vegas, A Zannetti, FC Bidard, S Delaloge, A Pradines, JL Canon, S Marques

Publikováno v: BMJ Open, Vol 12, Iss 3 (2022)

Introduction The combination of a CDK4/6 inhibitor with an aromatase inhibitor (AI) has recently become the gold standard for AI-sensitive first line treatment of oestrogen receptor-positive (ER+) HER2-negative (HER2−) advanced breast cancer. Howev

Externí odkaz: https://doaj.org/article/8faf6bbc845f4ceeb90674dd08e198da

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[Crisis situations: Ethical reflection on prioritization of care access in radiation oncology]

Autor: T, Haaser, Y, Constantinides, L, Lahmi, F, Huguet, R, de Crevoisier, C, Dejean, A, Escande, Y, Ghannam, P, Le Tallec, F, Lorchel, V, Mourman, S, Thureau, J L, Lagrange

Publikováno v: Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique. 26(6-7)

Understood as a disruption of the conditions of care practice according to established protocols or procedures, crisis situations in radiation oncology departments can have multiple causes. Their seriousness can sometimes impose changes in the decisi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::73cdde4fbf791f0c1d8d52204d7eb8cf
https://pubmed.ncbi.nlm.nih.gov/36075833

[Ethical stakes in palliative care in radiation oncology]

Autor: T, Haaser, Y, Constantinides, F, Huguet, R, De Crevoisier, C, Dejean, A, Escande, Y, Ghannam, L, Lahmi, P, Le Tallec, I, Lecouillard, F, Lorchel, S, Thureau, J L, Lagrange

Publikováno v: Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique. 25(6-7)

In 2021, the Ethics Commission of the SFRO has chosen the issue of the practice of palliative care in radiotherapy oncology. Radiation oncology plays a central role in the care of patients with cancer in palliative phase. But behind the broad name of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::c10476dc82e9faf0ead1e67317b9fefe
https://pubmed.ncbi.nlm.nih.gov/34400087

Démocratie sanitaire : le patient partenaire de sa prise en charge

Autor: A. Escande, F. Lorchel, T. Haaser, Jean-Léon Lagrange, S. Marty, S. Thureau, P. Le Tallec, Y. Constantinidès, Florence Huguet, Catherine Dejean

Publikováno v: Cancer/Radiothérapie
Cancer/Radiothérapie, Elsevier Masson, 2020, 24, pp.736-743. ⟨10.1016/j.canrad.2020.06.021⟩
Cancer/Radiothérapie, 2020, 24, pp.736-743. ⟨10.1016/j.canrad.2020.06.021⟩
Cancer Radiothérapie
Cancer Radiothérapie, Elsevier Masson, 2020, 24, pp.736-743. ⟨10.1016/j.canrad.2020.06.021⟩

Resume En 2019, le bureau de la Societe francaise de radiotherapie oncologique (SFRO) a cree une commission ethique. Sa mission est de proposer a notre communaute professionnelle des elements de reflexion a propos de questionnements ethiques, et d’

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5baa609c8e73ad5adc71fc654e47ca33
https://hal.archives-ouvertes.fr/hal-03491306