Zobrazeno 1 - 10
of 2 342
pro vyhledávání: '"F Lam"'
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract An accurate estimator of the real-time fatality rate is warranted to monitor the progress of ongoing epidemics, hence facilitating the policy-making process. However, most of the existing estimators fail to capture the time-varying nature of
Externí odkaz:
https://doaj.org/article/ab7aae43cdf34cccbbda747c9b104c83
Autor:
Lu Liu, Shuyao Yang, Kefeng Lin, Xiaoman Yu, Jiaqi Meng, Chao Ma, Zheng Wu, Yuchao Hao, Ning Chen, Qi Ge, Wenli Gao, Xiang Wang, Eric W.-F. Lam, Lin Zhang, Fangcheng Li, Bilian Jin, Di Jin
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-18 (2022)
Abstract Tumor immune microenvironment exerts a profound effect on the population of infiltrating immune cells. Tissue inhibitor of matrix metalloproteinase 1 (TIMP1) is frequently overexpressed in a variety of cells, particularly during inflammation
Externí odkaz:
https://doaj.org/article/3e6c09f24c63412a89b66e4fab5dbc27
Autor:
Vivian Weiwen Xue, Jeff Yat-Fai Chung, Philip Chiu-Tsun Tang, Alex Siu-Wing Chan, Travis Hoi-Wai To, Justin Shing-Yin Chung, Francis Mussal, Eric W.-F. Lam, Chunjie Li, Ka-Fai To, Kam-Tong Leung, Hui-Yao Lan, Patrick Ming-Kuen Tang
Publikováno v:
Molecular Therapy: Oncolytics, Vol 23, Iss , Pp 26-37 (2021)
Mincle is essential for tumor-associated macrophage (TAM)-driven cancer progression and represents a potential immunotherapeutic target for cancer. Nevertheless, the lack of a specific inhibitor has largely limited its clinical translation. Here, we
Externí odkaz:
https://doaj.org/article/1ce12fdf1f614834a957f8ffa6de827e
Publikováno v:
Atmospheric Chemistry and Physics, Vol 21, Pp 12895-12908 (2021)
An accurate emission inventory is a crucial part of air pollution management and is essential for air quality modelling. One source in an emission inventory, an industrial source, has been known with high uncertainty in both location and magnitude in
Externí odkaz:
https://doaj.org/article/9bc4c586570e494db8a32779be66b134
Autor:
Jiajun Xie, Zifeng Wang, Wenjun Fan, Youping Liu, Fang Liu, Xiangbo Wan, Meiling Liu, Xuan Wang, Deshun Zeng, Yan Wang, Bin He, Min Yan, Zijian Zhang, Mengjuan Zhang, Zhijie Hou, Chunli Wang, Zhijie Kang, Wenfeng Fang, Li Zhang, Eric W-F Lam, Xiang Guo, Jinsong Yan, Yixin Zeng, Mingyuan Chen, Quentin Liu
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 6, Iss 1, Pp 1-17 (2021)
Abstract Application of differentiation therapy targeting cellular plasticity for the treatment of solid malignancies has been lagging. Nasopharyngeal carcinoma (NPC) is a distinctive cancer with poor differentiation and high prevalence of Epstein-Ba
Externí odkaz:
https://doaj.org/article/6be212bae59246b1a0ce8e3bac882f2b
Autor:
Zijian Zhang, Deshun Zeng, Wei Zhang, Ailin Chen, Jie Lei, Fang Liu, Bing Deng, Junxiao Zhuo, Bin He, Min Yan, Xinxing Lei, Shulan Wang, Eric W.-F. Lam, Quentin Liu, Zifeng Wang
Publikováno v:
Cell Death and Disease, Vol 12, Iss 10, Pp 1-15 (2021)
Abstract Uncontrolled mitosis is one of the most important features of cancer, and mitotic kinases are thought to be ideal targets for anticancer therapeutics. However, despite numerous clinical attempts spanning decades, clinical trials for mitotic
Externí odkaz:
https://doaj.org/article/635c8173f8c740859566c26c14e0b828
Autor:
Hiu F. Yip, Debajyoti Chowdhury, Kexin Wang, Yujie Liu, Yao Gao, Liang Lan, Chaochao Zheng, Daogang Guan, Kei F. Lam, Hailong Zhu, Xuecheng Tai, Aiping Lu
Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
Diseases originate at the molecular-genetic layer, manifest through altered biochemical homeostasis, and develop symptoms later. Hence, symptomatic diagnosis is inadequate to explain the underlying molecular-genetic abnormality and individual genomic
Externí odkaz:
https://doaj.org/article/a8ffc15e1eb2481f86eca95a57bdcc24
Autor:
N. Zhao, X. Dong, K. Huang, J. S. Fu, M. T. Lund, K. Sudo, D. Henze, T. Kucsera, Y. F. Lam, M. Chin, S. Tilmes
Publikováno v:
Atmospheric Chemistry and Physics, Vol 21, Pp 8637-8654 (2021)
Black carbon (BC) emissions play an important role in regional climate change in the Arctic. It is necessary to pay attention to the impact of long-range transport from regions outside the Arctic as BC emissions from local sources in the Arctic were
Externí odkaz:
https://doaj.org/article/54d70902362147b49fcfa48e07b8de91
Autor:
Thang L. Pham, Jiucheng He, Azucena H. Kakazu, Jorgelina Calandria, Khanh V. Do, Robert Nshimiyimana, Ting F. Lam, Nicos A. Petasis, Haydee E. P. Bazan, Nicolas G. Bazan
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection that causes coronavirus disease 2019 (COVID-19) has resulted in a pandemic affecting the most vulnerable in society, triggering a public health crisis and economic co
Externí odkaz:
https://doaj.org/article/dc09ab38615546c8b5b456b05f0cc312
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract The acidic microenvironment of solid tumors induces the propagation of highly invasive and metastatic phenotypes. However, simulating these conditions in animal models present challenges that confound the effects of pH modulators on tumor pr
Externí odkaz:
https://doaj.org/article/9d05854102bc448b942458fcd7cb26a5