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of 4
pro vyhledávání: '"F L, Tyson"'
Autor:
E, Wickstrom, F L, Tyson
Publikováno v:
Ciba Foundation symposium. 209
The usual course of drug discovery begins with the demonstration of compound activity in cells and, usually, a lower level of activity in animals. Successive rounds of drug design may result in a compound with sufficient activity in animals to justif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0d72b0e6fb58801b8bc0464b30d21cc4
https://pubmed.ncbi.nlm.nih.gov/9383573
https://pubmed.ncbi.nlm.nih.gov/9383573
Autor:
C R, Herzog, E V, Soloff, A L, McDoniels, F L, Tyson, A M, Malkinson, A, Haugen-Strano, R W, Wiseman, M W, Anderson, M, You
Publikováno v:
Oncogene. 13(9)
The genes of murine cyclin D-dependent kinase inhibitors, p15INK4b and p16INK4a, are located in a region of chromosome 4 where overlapping deletions were found in lung adenocarcinomas. The p16INK4a gene uniquely consists of alternative first exons (E
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9ed3df0e259f80c231edacefe0b3098c
https://pubmed.ncbi.nlm.nih.gov/8934534
https://pubmed.ncbi.nlm.nih.gov/8934534
Publikováno v:
BioTechniques. 14(3)
The PCR has proven to be useful in the analysis of gene expression of specific mRNAs. Although PCR is able to detect rare mRNA transcripts following reverse transcription PCR, determining relative or absolute copy number can be difficult due to sampl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::cb384414308d7b7e66c4dc769cc9324f
https://pubmed.ncbi.nlm.nih.gov/7681298
https://pubmed.ncbi.nlm.nih.gov/7681298
Autor:
Lee Daly, John T. Soper, G. Cram, Jennie R. Crews, Russel E. Kaufman, Cinda M. Boyer, Kathy O'Briant, J. S. Haskill, W. C. Fowler, Robert C. Bast, F. L. Tyson
Publikováno v:
American journal of obstetrics and gynecology. 165(3)
Amplification of the c-erbB-2 protooncogene has been associated with a poor prognosis in human breast and ovarian cancers. Our study was undertaken to examine whether amplification, rearrangement, or overexpression of c-erbB-2 and other protooncogene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cabf28544ede1bccbd2e047c1ef35d88
https://pubmed.ncbi.nlm.nih.gov/1679963
https://pubmed.ncbi.nlm.nih.gov/1679963