Zobrazeno 1 - 10
of 114
pro vyhledávání: '"F L, Harwood"'
Autor:
Rosalina Das, Stavros Thomopoulos, David Amiel, Shelly E. Sakiyama-Elbert, Richard H. Gelberman, F. L. Harwood
Publikováno v:
The Journal of Hand Surgery. 33:1548-1557
Purpose Surgically repaired intrasynovial tendons are at greatest risk of failure in the first 3 weeks after surgery. Attempts to improve the strength of repair by modifying rehabilitation parameters have not always been successful. Manipulation of t
Publikováno v:
Journal of Applied Physiology. 69:902-906
To evaluate the protective role of the synovial sheath of the anterior cruciate ligament (ACL), we have developed a synovectomy model that exposes the ACL substance to the intra-articular environment with and without hemarthrosis. Histology and the l
Publikováno v:
Matrix. 9:421-427
A method utilizing the enzyme-linked immunosorbent assay (ELISA) is presented for quantitating fibronectin in periarticular soft tissues from rabbits. The concentrations of fibronectin were determined in the medial collateral ligament, anterior cruci
Autor:
Stavros Thomopoulos, F. L. Harwood, Shelly E. Sakiyama-Elbert, Melissa A. Zaegel, Matthew J. Silva, David Amiel, Rosalina Das, Richard H. Gelberman
Publikováno v:
Journal of orthopaedic research : official publication of the Orthopaedic Research Society. 25(10)
The purpose of this study was to promote fibroblast proliferation and collagen remodeling in flexor tendon repair through sustained delivery of platelet derived growth factor (PDGF-BB). The release kinetics of PDGF-BB from a novel fibrin matrix deliv
Autor:
Martin Lotz, Kohei Kobayashi, Randal S. Goomer, F. L. Harwood, H. Mishima, David Amiel, H. Moriya, Sanshiro Hashimoto
Publikováno v:
Journal of orthopaedic research : official publication of the Orthopaedic Research Society. 19(5)
Partial medial meniscectomy leads to tibial articular cartilage degeneration. Nitric oxide (NO) production increases with the development of osteoarthritis (OA) and has been shown to have a catabolic effect on chondrocytes. Since distribution of chon
Publikováno v:
The Iowa orthopaedic journal. 20
Perichondrium is recognized as a tissue with chondrogenic potential yielding cells which can be used for osteochondral repair. Factors which influence the proliferative ability and chondrocytic phenotype of such cells include age and presence of spec
Publikováno v:
The Iowa orthopaedic journal. 18
Exogenously administered growth factors such as platelet-derived growth factor (PDGF), transforming growth factor beta (TGF-beta) and basic fibroblast growth factor (bFGF) have been shown to affect connective tissue healing in vivo, but their intrins
Publikováno v:
Journal of orthopaedic research : official publication of the Orthopaedic Research Society. 15(6)
Our laboratory has developed a method for the repair of osteochondral defects by implanting cultured perichondrial cells attached to a biodegradable polylactic acid scaffold. The success of this approach depends in part on the proliferative character
Autor:
R D, Howard, C W, McIlwraith, G W, Trotter, B E, Powers, P R, McFadden, F L, Harwood, D, Amiel
Publikováno v:
American journal of veterinary research. 55(8)
Bilateral osteochondral defects (10 mm2 x 3 mm deep) were created on the distal articular surface of the radial carpal bone of ten, 2- to 3-year-old horses. One defect of each horse was repaired, using a sternal cartilage autograft (treated), and the
Publikováno v:
Journal of Orthopaedic Research. 7:486-493
Rapid degeneration of the anterior cruciate ligament (ACL) has been observed following acute ACL rupture. An understanding of this process might explain some of the poor clinical results of primary ACL repair. We created a surgical rabbit model of ac