Zobrazeno 1 - 10
of 62
pro vyhledávání: '"F Jon, Kull"'
Publikováno v:
mBio, Vol 15, Iss 12 (2024)
ABSTRACT Intestinal colonization and virulence factor production in response to environmental cues is mediated through several regulatory factors in Vibrio cholerae, including the highly conserved RNA-binding global regulatory protein CsrA. We have s
Externí odkaz:
https://doaj.org/article/2c3b330591144e74ab01fd8d3c8c14e8
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Enteric infections caused by the gram-negative bacteria enterotoxigenic Escherichia coli (ETEC), Vibrio cholerae, Shigella flexneri, and Salmonella enterica are among the most common and affect billions of people each year. These bacteria co
Externí odkaz:
https://doaj.org/article/534105fb0ec64ce69e4cffc37bd6633c
Autor:
Charles R. Midgett, F. Jon Kull
Publikováno v:
Advances in Experimental Medicine and Biology ISBN: 9783031229961
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6379c12f39aa8efe7246225be8228a36
https://doi.org/10.1007/978-3-031-22997-8_14
https://doi.org/10.1007/978-3-031-22997-8_14
Publikováno v:
ACS Med Chem Lett
[Image: see text] The chiral conformation that palmitoleic acid takes when it is bound to ToxT, the master regulator of virulence genes in the bacterial pathogen Vibrio cholerae, was used as inspiration to design a novel class of fatty acid mimetics.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a36462b90fa306aa6ee13402b23cbcde
https://pubmed.ncbi.nlm.nih.gov/34531958
https://pubmed.ncbi.nlm.nih.gov/34531958
Enterotoxigenic Escherichia coli (ETEC) is a common cause of diarrheal disease worldwide and a frequent cause of travelers’ diarrhea. In addition to the production of enterotoxins, studies with human volunteers established ETEC virulence is depende
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ae5137590f850d0bc0db72780b87c512
https://doi.org/10.1101/2020.10.05.326769
https://doi.org/10.1101/2020.10.05.326769
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-1 (2020)
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e1e23149540be0bf812e12f7f9db62c
https://doi.org/10.1038/s41598-020-69095-8
https://doi.org/10.1038/s41598-020-69095-8
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
ToxR is a transmembrane transcription factor that, together with its integral membrane periplasmic binding partner ToxS, is conserved across the Vibrio family. In some pathogenic Vibrios, including V. parahaemolyticus and V. cholerae, ToxR is require
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a4950186d3cd2dd133ae7311ffce5cc
Autor:
Salvador Almagro-Moreno, F. Jon Kull, Maria Pellegrini, Charles R. Midgett, Karen Skorupski, Ronald K. Taylor
Publikováno v:
Molecular Microbiology. 105:258-272
ToxR is a transmembrane transcription factor that is essential for virulence gene expression and human colonization by Vibrio cholerae. ToxR requires its operon partner ToxS, a periplasmic integral membrane protein, for full activity. These two prote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d936a3edde9755704e338a6edbb8f348
https://doi.org/10.1111/mmi.13699
https://doi.org/10.1111/mmi.13699
Autor:
Justin T. Cruite, Gabriela Kovacikova, Kenzie A. Clark, Anne K. Woodbrey, Karen Skorupski, F. Jon Kull
Publikováno v:
Communications Biology, Vol 2, Iss 1, Pp 1-9 (2019)
The AraC/XylS-family transcriptional regulator ToxT is the master virulence activator of Vibrio cholerae, the gram-negative bacterial pathogen that causes the diarrheal disease cholera. Unsaturated fatty acids (UFAs) found in bile inhibit the activit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::adb91d484d416a3132dc8fb3429d63fc
https://doi.org/10.1038/s42003-019-0686-x
https://doi.org/10.1038/s42003-019-0686-x
Autor:
Allen Wu, Anton Volchenkov, Ashleigh Provoost, F. Jon Kull, Caitlin Schwarz, Morgan E. D’Ausilio, Kristin Osika, Belinda Poh, Cole Morriello, Maureen Schwarz
Publikováno v:
The FASEB Journal. 34:1-1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ca77dc97d2d44f291e375d6de867b1e2
https://doi.org/10.1096/fasebj.2020.34.s1.09366
https://doi.org/10.1096/fasebj.2020.34.s1.09366