Zobrazeno 1 - 10
of 14
pro vyhledávání: '"F J de Sauvage"'
Publikováno v:
Molecular and Cellular Biology. 12:2581-2590
The natriuretic peptide receptors, NPR-A and NPR-B, are two members of the newly described class of receptor guanylyl cyclases. The kinaselike domain of these proteins is an important regulator of the guanylyl cyclase activity. To begin to understand
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::402a56303a61674950ad9f7782376a86
https://doi.org/10.1128/mcb.12.6.2581
https://doi.org/10.1128/mcb.12.6.2581
Publikováno v:
Blood. 92:2189-2191
To the Editor: Maintenance of an appropriate number of circulating platelets is required for hemostasis and blood coagulation. The control of platelet production is mediated by thrombopoietin (Tpo) through its effect on the proliferation of megakaryo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9d4e641cef12eced248aadeef0c758ad
https://doi.org/10.1182/blood.v92.6.2189
https://doi.org/10.1182/blood.v92.6.2189
Publikováno v:
Cancer research. 61(19)
Notch signaling has been widely demonstrated to be responsible for cell fate determination during normal development and implicated in human T-cell leukemia and mouse mammary carcinomas. Here we show that Notch signaling may be involved in prostatic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4afae1503f1cdc152a2d7dc198d81bc7
https://pubmed.ncbi.nlm.nih.gov/11585768
https://pubmed.ncbi.nlm.nih.gov/11585768
Publikováno v:
Stem cells (Dayton, Ohio). 16
Thrombopoietin is a lineage-dominant cytokine involved primarily in the control of platelet production. The physiological importance of thrombopoietin (TPO) in the regulation of megakaryocyte and platelet production was demonstrated by the production
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::915f1f7c56db9f63228173da3a8fed29
https://pubmed.ncbi.nlm.nih.gov/11012175
https://pubmed.ncbi.nlm.nih.gov/11012175
Publikováno v:
Blood. 92(1)
Recently, several lines of evidence have indicated an expanded role for thrombopoietin (TPO) and its receptor, c-mpl, in hematopoiesis. In addition to being the primary physiological regulator of platelet production, it is now apparent that TPO also
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6c9ba2c3094fcf20798e39cb687ae7db
https://pubmed.ncbi.nlm.nih.gov/9639492
https://pubmed.ncbi.nlm.nih.gov/9639492
Publikováno v:
Blood. 90(5)
The mechanisms that regulate circulating levels of thrombopoietin (Tpo) are incompletely understood. According to one favored model, the rate of Tpo synthesis is constant, whereas the serum concentration of free Tpo is modulated through binding to c-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f2eddffe7cfb7a5ec2e22f1f81e390bf
https://pubmed.ncbi.nlm.nih.gov/9292514
https://pubmed.ncbi.nlm.nih.gov/9292514
Autor:
P J, Fielder, P, Hass, M, Nagel, E, Stefanich, R, Widmer, G L, Bennett, G A, Keller, F J, de Sauvage, D, Eaton
Publikováno v:
Blood. 89(8)
Recent studies have shown that plasma thrombopoietin (TPO) levels appear to be directly regulated by platelet mass and that removal of plasma TPO by platelets via binding to the c-Mpl receptor is involved in the clearance of TPO in rodents. To help e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::79ea7ea1f57d4c886a1f86a9ff05a87e
https://pubmed.ncbi.nlm.nih.gov/9108396
https://pubmed.ncbi.nlm.nih.gov/9108396
Autor:
D L, Eaton, F J, de Sauvage
Publikováno v:
Experimental hematology. 25(1)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0e3db74bc32024a1b61117ddb12935f8
https://pubmed.ncbi.nlm.nih.gov/8989900
https://pubmed.ncbi.nlm.nih.gov/8989900
Publikováno v:
Leukemia. 10(12)
Thrombocytosis is a characteristic clinical feature in patients with myelocytic malignancies and chromosomal rearrangements of 3q21 and 3q26, sometimes called the '3q21q26 syndrome'. The function of thrombopoietin (TPO) in megakaryocytopoiesis and th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0c74984790d59f6aaaaf8e494fba3a10
https://pubmed.ncbi.nlm.nih.gov/8946927
https://pubmed.ncbi.nlm.nih.gov/8946927
Autor:
P J, Fielder, A L, Gurney, E, Stefanich, M, Marian, M W, Moore, K, Carver-Moore, F J, de Sauvage
Publikováno v:
Blood. 87(6)
The involvement of platelets and the c-mpl receptor in the regulation of thrombopoietin (TPO) plasma concentrations and tissue mRNA levels was investigated in both normal mice and mice defective in c-mpl (c-mpl-/-). Although c-mpl-/- mice have fewer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a932ff815711d011c3551745d137e8d0
https://pubmed.ncbi.nlm.nih.gov/9731084
https://pubmed.ncbi.nlm.nih.gov/9731084