Zobrazeno 1 - 10
of 44
pro vyhledávání: '"F J, Morrison"'
Autor:
A. H. Mansur, G. Christie, Alex F. Markham, P. Helms, D. T. Bishop, A. Turner, J. F. J. Morrison
Publikováno v:
Clinical & Experimental Allergy. 30:954-961
Background Raised serum immunoglobulin E (IgE) and bronchial hyperreactivity (BHR) are risk factors for the expression of the asthma phenotype. Previous studies have reported evidence for linkage between these traits and markers on the 5q23–33 cyto
Autor:
John Britton, K Richards, T. C. Li Kam Wa, A. H. Mansur, Ian D. Pavord, J. F. J. Morrison, G. A. Williams, D. A. Campbell, S. T. Holgate, Newton E. Morton
Publikováno v:
Clinical & Experimental Allergy. 29:1204-1208
Background Tumour necrosis factor (TNF) is a pivotal cytokine in the inflammation underlying asthma. The TNF gene is located in the polymorphic HLA class 3 region on chromosome 6p. Several polymorphisms in this region have been described and associat
Autor:
John F. J. Morrison
Publikováno v:
BLDE University Journal of Health Sciences, Vol 1, Iss 1, Pp 1-2 (2016)
Publikováno v:
QJM. 91:567-572
Phytohaemagglutinin (PHA)-induced T-cell proliferation is suppressed completely in steroid-sensitive asthma (SSA) by fluticasone propionate (FP). By contrast, in patients with steroid-resistant asthma (SRA), this proliferative response is only partia
Autor:
G G Anderson, J F J Morrison
Publikováno v:
Archives of Disease in Childhood. 78:488-496
In the past few years considerable progress has been made in understanding the pathogenesis of allergy at the cellular and subcellular level. In particular, advances in cell biology and DNA technology have shed light on the cell interactions that are
Publikováno v:
Clinical & Experimental Allergy. 28:442-448
OBJECTIVE: To determine the association between the beta2-adrenoceptor polymorphisms at amino acids 16 and 27 and markers of allergic disease and asthma per se in a random adult population, and to determine the degree of linkage disequilibrium existi
Publikováno v:
Clinical & Experimental Allergy. 28:141-150
Background Linkage studies have provided evidence for the presence of gene(s) in the 5q cytokine cluster region which control total serum immunoglobulin E (IgE) concentration, and bronchial hyperreactivity (BHR). However, the identification of the ge
Autor:
Jack P. Leek, Alan Norris, Alexander F. Markham, John F. J. Morrison, Roslan B. Harun, Kim Smith
Publikováno v:
Genomics. 42:349-352
SHC is an adapter protein in the Ras-MAPkinase pathway that is involved in the regulation of cell growth and differentiation. The p46 and p52 isoforms are thought to be produced by the use of two alternative translation initiation sites in a 3.4-kb t
Autor:
William R. Lindsay, F. J. Morrison
Publikováno v:
Journal of Applied Research in Intellectual Disabilities. 10:33-40
Relaxation techniques have been identified as reducing physiological and behavioural manifestations of anxiety. This study considered whether these reductions were related to similar reductions in the client's self-assessed experience of anxiety. Thi
Autor:
A, H Mansur, J, F J Morrison
Publikováno v:
Methods in molecular medicine. 44
In addition to important environmental factors, it is now well established that genetic factors contribute significantly to the development of asthma and atopy, accounting for between 30 and 60% of the predisposition (1-3). This genetic predispositio