Zobrazeno 1 - 10
of 52
pro vyhledávání: '"F J, Lejeune"'
Autor:
Thierry Lesimple, V. Nicolas, E. Lundström, P. Crompton, B. Gavillet, V. Grégoire, C. Robert, F. J. Lejeune, C. Lebbé
Publikováno v:
Annals of Oncology. 30:xi44
Background It has been shown that androgens are immunosuppressive. Androgen deprivation with GnRH agonists regenerates the thymus and its functions in adults, leading to increase in blood and lymphoid organ lymphocytes, in naive lymphocytes with expa
Autor:
F J, Lejeune, C, Rüegg
Publikováno v:
Bulletin du cancer. 93(8)
Recombinant human TNF (rhTNF) has a selective effect on endothelial cells in tumour angiogenic vessels. Its clinical use has been limited because of its property to induce vascular collapsus. TNF administration through isolated limb perfusion (ILP) f
Autor:
Nathalie Lassau, P. Terrier, A. Le Cesne, G. Antoni, C. Robert, Marcel Ricard, F. J. Lejeune, S. Bonvalot, E. Stoeckle, Andrea Cavalcanti, C. Le Pechoux, J.-Y. Blay, Jean Lumbroso, D. Vanel, Agnès Laplanche
Publikováno v:
Annals of Oncology : Official Journal of the European Society For Medical Oncology, vol. 16, no. 7, pp. 1061-1068
BACKGROUND: The optimal dose of TNF-alpha delivered by isolated limb perfusion (ILP) in patients with locally advanced soft tissue sarcoma is still unknown. PATIENTS AND METHODS: Randomised phase II trial comparing hyperthermic ILP (38-40 degrees ) w
Autor:
F J, Lejeune, B B, Kroon, F, Di Filippo, H J, Hoekstra, M, Santinami, D, Liénard, A M, Eggermont
Publikováno v:
Surgical oncology clinics of North America. 10(4)
Isolated limb perfusion (ILP) is a method of cancer treatment allowing the administration of high doses of anticancer agents in a limb surgically isolated from systemic circulation. By using continuous leakage monitoring and using the drug melphalan,
Autor:
P. Autier, J.-F. Dore, S. Negrier, D. Lienard, R. Panizzon, F. J. Lejeune, D. Guggisberg, A. M. M. Eggermont
Publikováno v:
Journal of the National Cancer Institute. 91(15)
In epidemiologic studies, sunscreen use is associated with increased risk of cutaneous melanoma, basal cell skin cancer, and higher numbers of nevi. It has been proposed that sunscreens may encourage prolonged sun exposure because they delay sunburn
Autor:
F J, Lejeune
Publikováno v:
Bulletin du cancer. 86(1)
Autor:
Heimen Schraffordt Koops, J. Góhl, A. M. M. Eggermont, M. Vaglini, D. Ruiter, Bin B. R. Kroon, S. Suciu, F. Di Filippo, J. F. Thompson, F. J. Lejeune, E. T. Krementz
Publikováno v:
Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 16(9)
PURPOSE Patients with primary cutaneous melanoma > or = 1.5 mm in thickness are at high risk of having regional micrometastases at the time of initial surgical treatment. A phase III international study was designed to evaluate whether prophylactic i
Publikováno v:
Seminars in surgical oncology. 14(3)
In advanced melanoma of the limbs with in-transit metastasis, melphalan with isolated limb perfusion (M-ILP) produces around 50% complete remissions (CR). The combination of melphalan with tumour necrosis factor-alpha (TNFalpha) and interferon-gamma
Autor:
H, Schraffordt Koops, A M, Eggermont, D, Liénard, B B, Kroon, H J, Hoekstra, A N, Van Geel, O E, Nieweg, F J, Lejeune
Publikováno v:
Seminars in surgical oncology. 14(3)
Hyperthermic isolated limb perfusion (HILP) with various chemotherapeutic agents has been used for the local treatment of high-grade soft tissue sarcomas (STS) of the extremities, but in most cases, with a disappointing result. Most such regimens cer
Publikováno v:
European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology. 23(6)
This article outlines and discusses the principles of the guidelines for the management of malignant melanoma by surgeons. The guidelines are based, in large part, on the consensus of the Dutch Melanoma Working Party that was revised in 1997. The art