Increased synovial immunohistochemistry reactivity of TGF-β1 in erosive peripheral psoriatic arthritis

Autor: Jose A. Pinto Tasende, M. Fernandez-Moreno, M. E. Vazquez-Mosquera, J. C. Fernandez-Lopez, N. Oreiro-Villar, F. J. De Toro Santos, F. J. Blanco-García

Publikováno v: BMC Musculoskeletal Disorders, Vol 24, Iss 1, Pp 1-14 (2023)

Abstract Background Immune and non-immune cells contribute to the pathology of chronic arthritis, and they can contribute to tissue remodeling and repair as well as disease pathogenesis. The present research aimed to analyze inflammation and bone des

Externí odkaz: https://doaj.org/article/eb9fb21efff840b89fba355301d04029

POS0226 DEFICIENT CHAPERONE-MEDIATED AUTOPHAGY CONTRIBUTES TO JOINT DAMAGE IN OSTEOARTHRITIS

Autor: I. Lorenzo, U. Nogueira-Recalde, C. Garcia-Dominguez, N. Oreiro, J. A. Pinto Tasende, M. Lotz, F. J. Blanco, B. Carames

Publikováno v: Annals of the Rheumatic Diseases. 81:349.1-350

BackgroundIn Osteoarthritis (OA), defects in macroautophagy are evident and precede joint damage. Indeed, pharmacological activation of macroautophagy protects against joint damage and disease.ObjectivesTherefore, identifying hallmarks associated wit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::34b9c23becf2004c83cc1c733e5312ab
https://doi.org/10.1136/annrheumdis-2022-eular.1939

POS0438 IDENTIFICATION OF ANTI-CYTOKINE AUTOANTIBODIES WITH POTENTIAL TO PREDICT FLARE IN RHEUMATOID ARTHRITIS PATIENTS UNDERGOING BIOLOGICAL THERAPIES: A DISCOVERY STUDY

Autor: L. Lourido, P. Quaranta, R. Paz González, V. Calamia, J. D. D. Cañete, B. Fernandez, I. González-Álvaro, A. Gonzalez, J. L. Pablos, F. J. Blanco, C. Ruiz-Romero

Publikováno v: Annals of the Rheumatic Diseases. 81:474.1-474

BackgroundThe presence of anti-cytokine autoantibodies (ACAAs) seems to be a physiologic mechanism to control the immune response and regulate cytokine activity. Biological therapies also regulate cytokine activities and have greatly improved the qua

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3cd986f6889e57c24844e09e8b31a6df
https://doi.org/10.1136/annrheumdis-2022-eular.4371

OP0115 mtDNA D-LOOP VARIANT m.16519C INCREASES THE RISK OF RAPID PROGRESSION OF KNEE OSTEOARTHRITIS. A META-ANALYSIS AND FUNCTIONAL STUDY

Autor: A. Durán-Sotuela, M. Fernandez-Moreno, T. Hermida Gómez, P. Ramos-Louro, S. Relaño-Fernandez, V. Suárez-Ulloa, V. Balboa-Barreiro, N. Oreiro, C. Vaamonde-García, J. Vázquez-García, F. J. Blanco, I. Rego-Perez

Publikováno v: Annals of the Rheumatic Diseases. 81:75.2-76

BackgroundThe development of a tool capable of identifying patients suffering the rapid progressive knee Osteoarthritis (RPOA) was established as a goal to implement prevention strategies and to include them in clinical trials. Previous studies showe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::29e53c7bfa7bb8730360a0a7e8d523f6
https://doi.org/10.1136/annrheumdis-2022-eular.4403

Multicentre propensity score-matched analysis of conventional versus extended abdominoperineal excision for low rectal cancer

Autor: H Ortiz, M A Ciga, P Armendariz, E Kreisler, A Codina-Cazador, J Gomez-Barbadillo, E Garcia-Granero, J V Roig, S Biondo, J Lujan, D Fraccalvieri, P Armendáriz, M de Miguel, A Espí, A Codina, M D Ruiz, E Espin, R Palasí, A Parajo, I Camps, M Piñol, E Pellicer, V Viciano, E Alonso, M Pera, T García, E Casal, J Garcia, M Rodríguez, Á Reina, J Roig, J Errasti, J A Múgica, J Gomez, R Rada, M Orelogio, N Uribe, J de Dios Franco, A Arroyo, J E Sierra, P Hernandez, J Paredes, G Martínez, M Garcia, G Carreño, J Cifuentes, J Monzón, O Maseda, D Huerga, C Pavel, F Gris, I Segura, P Palma, J G Díaz, J L Jiménez, F Pérez, V Portugal, J C Bernal, F Lluis, L Capitán, N Cáceres, J Martínez, A Estévez, M V Maestre, J M Díaz, M Reig, A Amaya, J A Carmona, F J Jiménez, D Ribé i Serrat, I Prieto, D Garcia, T González de Francisco, A Turienzo, M Martinez, S del Valle, P Parra, F Romero, A Garcea, X Rodamilans de la O, A Pérez, G Ais, L Ortiz de Zarate, J Sánchez, R Estevan, A Sueiras, A Lamiquiz, A Larzabal, J Die, A Solana, F J Blanco, A M Lage, J L Domínguez, P Dujovne, N Palencia, R García, R Adell, R Martínez, A M Huidobro, C Pastor, J Á Garijo, Á Carrillo, M del Coral de la Vega, M López

Publikováno v: BRITISH JOURNAL OF SURGERY
r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe
instname

Background Abdominal perineal excision (APE) was originally described with levator ani removal for rectal cancer. An even wider, more aggressive extralevator resection for APE has been proposed. Although some surgeons are performing a very wide ‘ex

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c603d6c25b9a53f4e5b68ce8ffe529d
https://doi.org/10.1002/bjs.9522