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of 369
pro vyhledávání: '"F Homo-Delarche"'
Autor:
F. Homo-Delarche
Publikováno v:
Brazilian Journal of Medical and Biological Research, Vol 34, Iss 4, Pp 437-447 (2001)
Despite extensive genetic and immunological research, the complex etiology and pathogenesis of type I diabetes remains unresolved. During the last few years, our attention has been focused on factors such as abnormalities of islet function and/or mic
Externí odkaz:
https://doaj.org/article/0ea8a785c5a147a0ae3e446fa624ecf1
Autor:
S, Charré, J G M, Rosmalen, C, Pelegri, V, Alves, P J M, Leenen, H A, Drexhage, F, Homo-Delarche
Publikováno v:
Histology and histopathology. 17(2)
Dendritic cell (DC), macrophage (Mphi) and lymphocyte infiltrations have been observed in normal human perinatal pancreata, but have never been investigated so early in control mice. In type 1 diabetes-prone NOD mice, these cells are thought to infil
Autor:
Seunghee Cha, H. Nagashima, J. Brayer, S C van Blockland, F Homo-Delarche, M A Versnel, Michael G. Humphreys-Beher, Ammon B. Peck
Publikováno v:
Experimental and clinical immunogenetics. 18(3)
Objectives: Salivary gland organogenesis was evaluated in NOD mice, an animal model for autoimmune exocrinopathy, to determine when disease onset is first present in the target tissues. Methods: Submandibular glands were removed for histological, imm
Autor:
F, Homo-Delarche
Publikováno v:
Diabetesmetabolism. 23(6)
The pathogenesis of autoimmune insulin-dependent (Type 1) diabetes mellitus (IDDM) is far from being resolved, despite extensive genetic and immunological research. However, recent experimental data from immune and endocrine studies using spontaneous
Publikováno v:
Endocrinology. 139(3)
Because few data were available on glucose homeostasis at the early prediabetic stage in the nonobese diabetic (NOD) mouse, we investigated glycemia, insulinemia, and pancreatic insulin content under basal conditions in both sexes of 4-, 6-, and 8-we
Autor:
F, Homo-Delarche
Publikováno v:
Diabetesmetabolism. 23(3)
beta-Cell function in non-insulin dependent diabetes mellitus (NIDDM) or type II diabetes, in particular during the prediabetic stage, has been more extensively investigated than in insulin-dependent diabetes mellitus (IDDM) or type I diabetes. Recen
Publikováno v:
Journal of autoimmunity. 8(6)
Prolactin (PRL) is well known for its stimulatory effects on various components of the immune response. Experimentally induced high levels of PRL have been shown to correlate with the worsening of several autoimmune diseases. In contrast, lowering PR
Autor:
H, Letur-Könirsch, A, Raoul-Duval, A, Cabau, O, Bomsel-Helmreich, W, al Mufti, F, Homo-Delarche
Publikováno v:
Comptes rendus de l'Academie des sciences. Serie III, Sciences de la vie. 318(6)
By acting on the neuroendocrine system during the stress response, life events may greatly affect homeostasis and favor the appearance of disease. Here, we describe a relationship between stressful life events and premature ovarian failure. From a me
Publikováno v:
European cytokine network. 6(2)
Insulin-dependent diabetes mellitus (IDDM) is characterized by a progressive autoimmune destruction of pancreatic beta cells. Many data suggest that interleukin 1 (IL-1) plays a fundamental role in the pathogenesis of the disease. In the nonobese dia
Autor:
F Homo-Delarche, Y Wang, François Leboulenger, L Vaglini, Georges Pelletier, J M Conlon, Hubert Vaudry, B Kerdelhue
Publikováno v:
Scopus-Elsevier
The distribution of tachykinin-like immunoreactivity (LI) was studied in the adrenal gland of the frog Rana ridibunda using the immunofluorescence technique. A dense network of varicose fibers immunoreactive to both substance-P (SP) and neurokinin-A