Výsledky vyhledávání - "F H H Leenen"

Epicardial adipose tissue and cardiometabolic risk factors in overweight and obese children and adolescents

Autor: I. Schusterova, F. H. H. Leenen, J. Takacova, A. Jurko, F. Sabol

Publikováno v: Pediatric Obesity. 9:63-70

SummaryWhat is already known about this subject The prevalence of childhood obesity has increased markedly in the past 2 decades. Abdominal fat is a better predictor of risk than body mass index. Waist circumference (WC) as a measure of abdominal fat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::132ad811b037dcae7e0cb8205dedde4a
https://doi.org/10.1111/j.2047-6310.2012.00134.x

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Prevention of salt induced hypertension and fibrosis by angiotensin converting enzyme inhibitors in Dahl S rats

Autor: B Liang, F H H Leenen

Publikováno v: British Journal of Pharmacology. 152:903-914

Background and purpose: In Dahl S rats, high salt increases activity of the tissue renin-angiotensin-aldosterone system (RAAS) in the CNS, heart and kidneys. Here, we assessed the effects of chronic angiotensin converting enzyme (ACE) inhibition on s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::69e26641a35b4d96dea9a3c80503508f
https://doi.org/10.1038/sj.bjp.0707472

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Epicardial adipose tissue and cardiometabolic risk factors in overweight and obese children and adolescents

Autor: I, Schusterova, F H H, Leenen, A, Jurko, F, Sabol, J, Takacova

Publikováno v: Pediatric obesity. 9(1)

What is already known about this subject The prevalence of childhood obesity has increased markedly in the past 2 decades. Abdominal fat is a better predictor of risk than body mass index. Waist circumference (WC) as a measure of abdominal fat has li

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::c546a777fe633824da28b50d060424ff
https://pubmed.ncbi.nlm.nih.gov/23504985

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Enalapril suppresses normal accumulation of elastin and collagen in cardiovascular tissues of growing rats

Autor: F. W. Keeley, Adel B. Elmoselhi, F. H. H. Leenen

Publikováno v: American Journal of Physiology-Heart and Circulatory Physiology. 262:H1013-H1021

We have investigated the effect of enalapril, an angiotensin converting-enzyme (ACE) inhibitor, on the accumulation of ventricular and vascular collagen and elastin in young, growing rats. Beginning at either 4 or 10 wk of age, male Wistar rats were

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::088d0e0f2c57b1f8db9d550ede9005c6
https://doi.org/10.1152/ajpheart.1992.262.4.h1013

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Effects of Antihypertensive Drug Classes on Regression of Connective Tissue Components of Hypertension

Autor: F. H. H. Leenen, Adel B. Elmoselhi, F. W. Keeley

Publikováno v: Journal of Cardiovascular Pharmacology. 17:S64-S69

Hypertension leads to structural and functional adaptations which, although initially protective for the cardiovascular system, ultimately work to sustain and reinforce the hypertensive state. Although blood pressure (BP) may be effectively lowered b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5ab12f5779b80fb5548dde9804912ec
https://doi.org/10.1097/00005344-199117002-00014

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Cardiac volume load as a determinant of the response of cardiac mass to antihypertensive therapy

Autor: F. H. H. Leenen, J. Tsoporis

Publikováno v: European Heart Journal. 11:100-106

Whereas chronic pressure overload induces left ventricular hypertrophy in a predictable way, the same lowering of systolic blood pressure by different antihypertensive drug classes is not associated with the same regression of LV mass. In particular,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6352011b67b4ba6fdf2284ae030e04f7
https://doi.org/10.1093/eurheartj/11.suppl_g.100

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The impact of one or two missed doses on the duration of action of combined perindopril and indapamide

Autor: Martin G. Myers, F H H Leenen

Publikováno v: Journal of human hypertension. 21(1)

To evaluate the persistence of the antihypertensive effect of perindopril 4 mg+indapamide 1.25 mg once daily for up to 72 h using the 'missed-dose' technique. Hypertensive patients were initially treated with perindopril 2 mg+indapamide 0.625 mg once

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f967d7319c1d829ba84605d0d2a05cd6
https://pubmed.ncbi.nlm.nih.gov/17066085

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Antihypertensive efficacy of the ACE-inhibitor perindopril in the elderly

Autor: F H H Leenen, McNally Cf, Tanner J

Publikováno v: Journal of human hypertension. 14(5)

To assess the antihypertensive efficacy of the angiotensin-converting enzyme (ACE)-inhibitor, perindopril, in the elderly, patients65 years of age with supine diastolic blood pressure (BP)or =90 andor =110 mm Hg at the end of a 4-week placebo washout

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1117cb1cee11b441e4d3215c2fd8bf39
https://pubmed.ncbi.nlm.nih.gov/10822319

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Effects of age on cardiovascular responses to adrenaline in man

Autor: F. H. H. Leenen, Michel White

Aims Whereas the effects of ageing on β-receptor mediated responses have been extensively studied in vitro and in vivo using the β-adrenoceptor agonist isoprenaline, little is known regarding ageing induced changes in responses to endogenous catech

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68d7aebaa508af9a00a2199e1897a3ec
https://europepmc.org/articles/PMC2042753/

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