Zobrazeno 1 - 10
of 100
pro vyhledávání: '"F H, Ruddle"'
Publikováno v:
Molecular Biology and Evolution. 14:843-853
In vertebrates and the cephalochordate, amphioxus, the closest vertebrate relative, Hox genes are linked in a single cluster. Accompanying the emergence of higher vertebrates, the Hox gene cluster duplicated in either a single step or multiple steps,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::408c04cf4aa598dbb373de1348c61443
https://doi.org/10.1093/oxfordjournals.molbev.a025825
https://doi.org/10.1093/oxfordjournals.molbev.a025825
Publikováno v:
Development. 111:1109-1120
In mouse development, the paternal allele of the X-linked gene Pgk-1 initiates expression on day 6, two days later than the maternal allele, which is activated on day 4. The different timing of expression of the maternal and paternal alleles may be d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fa4e7ec9e023753c67a33e37d4d1548
https://doi.org/10.1242/dev.111.4.1109
https://doi.org/10.1242/dev.111.4.1109
Autor:
A A, Fienberg, C, Nordstedt, H G, Belting, A J, Czernik, A C, Nairn, S, Gandy, P, Greengard, F H, Ruddle
Publikováno v:
The Journal of experimental zoology. 285(1)
In an effort to characterize the signal transduction mechanisms that operate to regulate homeodomain protein function, we have analyzed the phosphorylation state of two homeodomain proteins, Hoxb-6 and Hoxc-8, in vitro and in vivo. The baculovirus ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b8107e0b4d1bfe046c58cec12f4a5e54
https://pubmed.ncbi.nlm.nih.gov/10327653
https://pubmed.ncbi.nlm.nih.gov/10327653
Autor:
F H, Ruddle
Publikováno v:
Japanese journal of cancer research : Gann. 89(12)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9f2ed2d82349fbdb97b7263b28c1657a
https://pubmed.ncbi.nlm.nih.gov/10081483
https://pubmed.ncbi.nlm.nih.gov/10081483
Publikováno v:
The Journal of experimental zoology. 282(1-2)
Hox genes are expressed in dynamic patterns during embryogenesis consistent with their role in axial specifications. To study the distribution of mouse Hoxc8, a homeodomain containing protein, we raised monoclonal antibodies against the least conserv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::32edae4c50234532746050202297e336
https://pubmed.ncbi.nlm.nih.gov/9723177
https://pubmed.ncbi.nlm.nih.gov/9723177
Publikováno v:
The Journal of experimental zoology. 280(1)
The mammalian Hox clusters arose by duplication of a primordial cluster. The duplication of Hox clusters created redundancy within cognate groups, allowing for change in function over time. The lamprey, Petromyzon marinus, occupies an intermediate po
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0b7ac75c302a8d74c5ac489c04638f67
https://pubmed.ncbi.nlm.nih.gov/9437854
https://pubmed.ncbi.nlm.nih.gov/9437854
Publikováno v:
Development (Cambridge, England). Supplement.
Homeobox cluster genes (Hox genes) are highly conserved and can be usefully employed to study phyletic relationships and the process of evolution itself. A phylogenetic survey of Hox genes shows an increase in gene number in some more recently evolve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0fc4152122d960325e3f656bfa38bd62
https://pubmed.ncbi.nlm.nih.gov/7579516
https://pubmed.ncbi.nlm.nih.gov/7579516
Autor:
C S, Shashikant, M F, Utset, S M, Violette, T L, Wise, P, Einat, M, Einat, J W, Pendleton, K, Schughart, F H, Ruddle
Publikováno v:
Critical reviews in eukaryotic gene expression. 1(3)
Following the discovery of the homeobox as a conserved sequence in developmentally important genes of Drosophila, a plethora of such sequences have been identified in evolutionarily distant organisms. Among mammals, the mouse homeobox genes have been
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::814480d13050f05cb21c0fd673f5d066
https://pubmed.ncbi.nlm.nih.gov/1686978
https://pubmed.ncbi.nlm.nih.gov/1686978
Publikováno v:
Biotechnology (Reading, Mass.). 16
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::47ffa693aef32607ac16b3188699b9f3
https://pubmed.ncbi.nlm.nih.gov/1672506
https://pubmed.ncbi.nlm.nih.gov/1672506
Autor:
R. E. K. Fournier, F. H. Ruddle
Publikováno v:
Proceedings of the National Academy of Sciences. 74:319-323
In this report, we describe the production and characterization of proliferating hybrid cell populations generated by fusion of murine microcells with intact mouse, Chinese hamster, and human recipient cells. The microcell hybrids so produced contain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a6bfdeceac0526fb708fe73588ca868
https://doi.org/10.1073/pnas.74.1.319
https://doi.org/10.1073/pnas.74.1.319