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pro vyhledávání: '"F H, Geisen"'
Autor:
A L, Petzer, F H, Geisen, R, Bilgeri, U, Zilian, M, Haun, M, Herold, H, Braunsteiner, G, Konwalinka
Publikováno v:
Experimental hematology. 23(6)
As neutropenia is a common side effect of treatment with 2-chlorodeoxyadenosine (2-CdA), we investigated the myelosuppressive action of 2-CdA in Dexter-type human long-term bone marrow cultures (LTBMCs). LTBMCs were incubated with varying doses of 2-
Autor:
A L, Petzer, R, Bilgeri, U, Zilian, M, Haun, F H, Geisen, I, Pragnell, H, Braunsteiner, G, Konwalinka
Publikováno v:
Blood. 78(10)
Previous studies have shown that 2-chloro-2'-deoxyadenosine (CdA) is markedly toxic to normal and malignant human lymphocytes in vitro and in vivo. Recent clinical trials have shown that CdA is a very promising drug for the treatment of lymphoid mali